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This article aims to provide a fresh approach to the study of hypercorrection, the misguided application of a real or imagined rule – typically in response to prescriptive pressure – in which the speaker's attempt to be ‘correct’ leads to an ‘incorrect’ result. Instead of more familiar sources of information on hypercorrection such as attitude elicitation studies and prescriptive commentary, insights are sought from quantitative and qualitative data extracted from the 2-billion-word Global Web-based English corpus (GloWbE; Davies 2013). Five categories are investigated: case-marked pronouns, -ly and non-ly adverbs, agreement with number-transparent nouns, (extended uses of) irrealis were, and ‘hyperforeign’ noun suffixation. The nature and extent of hypercorrection in these categories, across the twenty English varieties represented in GloWbE, are investigated and discussed. Findings include a tendency for hypercorrection to be more common in American than in British English, and more prevalent in the ‘Inner Circle’ (IC) than in the ‘Outer Circle’ (OC) varieties (particularly with established constructions which have been the target of institutionalised prescriptive commentary over a long period of time).
The first demonstration of laser action in ruby was made in 1960 by T. H. Maiman of Hughes Research Laboratories, USA. Many laboratories worldwide began the search for lasers using different materials, operating at different wavelengths. In the UK, academia, industry and the central laboratories took up the challenge from the earliest days to develop these systems for a broad range of applications. This historical review looks at the contribution the UK has made to the advancement of the technology, the development of systems and components and their exploitation over the last 60 years.
We hold these truths to be self-evident, that all men are created equal; that they are endowed by their Creator with inherent and unalienable Rights; that among these, are Life, Liberty, and the pursuit of Happiness. (United States Declaration of Independence, adopted by Congress, 4 July 1776)
The history of human rights in the United States has been a paradox. Despite the theoretical adherence to equal human rights in the foundation documents of the country itself, in practice they were not extended to many sections of the population – in particular African Americans and Native Americans. Indeed, George Washington and Thomas Jefferson (the main author of the Declaration of Independence) were themselves owners of black slaves and this activity remained central to economic development until finally abolished in 1865 after a protracted and bloody civil war. For a century after this abolition many in the white population refused to see African Americans as equal or, more alarmingly, even human. Crucially, despite bringing an end to slavery, Abraham Lincoln is a part of this national paradox.
I will say then that I am not, nor ever have been in favour of bringing about in any way the social and political equality of the white and black races … nor ever have been in favour of making voters or jurors of negroes, nor of qualifying them to hold office, nor to intermarry with white people. (Abraham Lincoln, 18 September 1858 – Fourth Debate with Stephen A. Douglas at Charleston, Illinois)
After the Civil War and Reconstruction, the lot of African Americans in the southern states was not much better than before ‘emancipation’. The initial rights granted to former slaves were gradually eroded in the former Confederacy, enforced by the influence and violence of the Ku Klux Klan through exclusions, imprisonment, beatings and lynchings. Indeed, systematic lynching of African Americans from 1890 to 1920 amounted to over 4,000 murders and major riots between white supremacists and African Americans were ongoing, with particularly heavy casualties in Memphis and New Orleans in 1866 (Zinn and Buhle, 2008: 158). Facing this history down was seen on occasion, with an early attempt coming from President Ulysses S. Grant, who took strong action via the Justice Department – which he set up in 1870 – and used troops against the Klan.
The reported associations between birth weight and childhood cardiovascular disease (CVD) risk factors have been inconsistent. In this study, we investigated the relationship between birth weight and CVD risk factors at 11 years of age. This study used longitudinally linked data from three cross-sectional datasets (N = 22,136) in West Virginia; analysis was restricted to children born full-term (N = 19,583). The outcome variables included resting blood pressure [systolic blood pressure (SBP), diastolic blood pressure (DBP)] and lipid profile [total cholesterol (TC), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, non-HDL, and triglycerides (TG)]. Multiple regression analyses were performed, adjusting for child’s body mass index (BMI), sociodemographics, and lifestyle characteristics. Unadjusted analyses showed a statistically significant association between birth weight and SBP, DBP, HDL, and TG. When adjusted for the child’s BMI, the association between birth weight and HDL [b = 0.14 (95% CI: 0.11, 0.18) mg/dl per 1000 g increase] and between birth weight and TG [b = –0.007 (–0.008, –0.005) mg/dl per 1000 g increase] remained statistically significant. In the fully adjusted model, low birth weight was associated with higher LDL, non-HDL, and TGs, and lower HDL levels. The child’s current BMI at 11 years of age partially (for HDL, non-HDL, and TG) and fully mediated (for SBP and DBP) the relationship between birth weight and select CVD risk factors. While effects were modest, these risk factors may persist and amplify with age, leading to potentially unfavorable consequences in later adulthood.
As referrals to specialist palliative care (PC) grow in volume and diversity, an evidence-based triage method is needed to enable services to manage waiting lists in a transparent, efficient, and equitable manner. Discrete choice experiments (DCEs) have not to date been used among PC clinicians, but may serve as a rigorous and efficient method to explore and inform the complex decision-making involved in PC triage. This article presents the protocol for a novel application of an international DCE as part of a mixed-method research program, ultimately aiming to develop a clinical decision-making tool for PC triage.
Method
Five stages of protocol development were undertaken: (1) identification of attributes of interest; (2) creation and (3) execution of a pilot DCE; and (4) refinement and (5) planned execution of the final DCE.
Result
Six attributes of interest to PC triage were identified and included in a DCE that was piloted with 10 palliative care practitioners. The pilot was found to be feasible, with an acceptable cognitive burden, but refinements were made, including the creation of an additional attribute to allow independent analysis of concepts involved. Strategies for recruitment, data collection, analysis, and modeling were confirmed for the final planned DCE.
Significance of results
This DCE protocol serves as an example of how the sophisticated DCE methodology can be applied to health services research in PC. Discussion of key elements that improved the utility, integrity, and feasibility of the DCE provide valuable insights.
Survival into adult life in patients with aortic coarctation is typical following surgical and catheter-based techniques to relieve obstruction. Late sequelae are recognised, including stroke, hypertension, and intracerebral aneurysm formation, with the underlying mechanisms being unclear. We hypothesised that patients with a history of aortic coarctation may have abnormalities of cerebral blood flow compared with controls.
Methods
Patients with a history of aortic coarctation underwent assessment of cerebral vascular function. Vascular responsiveness of intracranial vessels to hypercapnia and degree of cerebral artery stiffness using Doppler-derived pulsatility indices were used. Response to photic stimuli was used to assess neurovascular coupling, which reflects endothelial function in response to neuronal activation. Patient results were compared with age- and sex-matched controls.
Results
A total of 13 adult patients (males=10; 77%) along with 13 controls underwent evaluation. The mean age was 36.1±3.7 years in the patient group. Patients with a background of aortic coarctation were noted to have increased pulse pressure on blood pressure assessment at baseline with increased intracranial artery stiffness compared with controls. Patients with a history of aortic coarctation had less reactive cerebral vasculature to hypercapnic stimuli and impaired neurovascular coupling compared with controls.
Results
Adult patients with aortic coarctation had increased intracranial artery stiffness compared with controls, in addition to cerebral vasculature showing less responsiveness to hypercapnic and photic stimuli. Further studies are required to assess the aetiology and consequences of these documented abnormalities in cerebral blood flow in terms of stroke risk, cerebral aneurysm formation, and cognitive dysfunction.
Strategies for the involvement of primary care in the management of patients with presumed or diagnosed dementia are heterogeneous across Europe. We wanted to explore attitudes of primary care physicians (PCPs) when managing dementia: (i) the most popular cognitive tests, (ii) who had the right to initiate or continue cholinesterase inhibitor or memantine treatment, and (iii) the relationship between the permissiveness of these rules/guidelines and PCP's approach in the dementia investigations and assessment.
Methods:
Key informant survey. Setting: Primary care practices across 25 European countries. Subjects: Four hundred forty-five PCPs responded to a self-administered questionnaire. Two-step cluster analysis was performed using characteristics of the informants and the responses to the survey. Main outcome measures: Two by two contingency tables with odds ratios and 95% confidence intervals were used to assess the association between categorical variables. A multinomial logistic regression model was used to assess the association of multiple variables (age class, gender, and perceived prescription rules) with the PCPs’ attitude of “trying to establish a diagnosis of dementia on their own.”
Results:
Discrepancies between rules/guidelines and attitudes to dementia management was found in many countries. There was a strong association between the authorization to prescribe dementia drugs and pursuing dementia diagnostic work-up (odds ratio, 3.45; 95% CI 2.28–5.23).
Conclusions:
Differing regulations about who does what in dementia management seemed to affect PCP's engagement in dementia investigations and assessment. PCPs who were allowed to prescribe dementia drugs also claimed higher engagement in dementia work-up than PCPs who were not allowed to prescribe.
Colloquialisation, a process by which ‘writing becomes more like speech’, has been identified as a powerful discourse-pragmatic mechanism driving grammatical change in native English varieties. The extent to which colloquialisation is a factor in change in non-native varieties has seldom been explored. This article reports the findings of a corpus-based study of colloquialisation in Philippine English (PhilE), alongside its ‘parent variety’, American English (AmE). Adopting a bottom-up approach, a comprehensive measure was derived to determine the degree to which a text prefers grammatical features typical of speech and disprefers those typical of writing. This measure was then used to compare and contrast texts in a parallel, multi-register corpus of PhilE and AmE sampled for the 1960s and 1990s. Evidence for colloquialisation was found to vary across registers. While Philippine press editorials and American fiction show a clear colloquialising tendency, learned writing does not show remarkable changes irrespective of variety. The evolution of PhilE registers cannot be explained by a simple process involving emulation of AmE. The patterns uncovered reflect the uniqueness of the sociohistorical circumstances in which PhilE has evolved.
The anticipated release of EnlistTM cotton, corn, and soybean cultivars likely will increase the use of 2,4-D, raising concerns over potential injury to susceptible cotton. An experiment was conducted at 12 locations over 2013 and 2014 to determine the impact of 2,4-D at rates simulating drift (2 g ae ha−1) and tank contamination (40 g ae ha−1) on cotton during six different growth stages. Growth stages at application included four leaf (4-lf), nine leaf (9-lf), first bloom (FB), FB + 2 wk, FB + 4 wk, and FB + 6 wk. Locations were grouped according to percent yield loss compared to the nontreated check (NTC), with group I having the least yield loss and group III having the most. Epinasty from 2,4-D was more pronounced with applications during vegetative growth stages. Importantly, yield loss did not correlate with visual symptomology, but more closely followed effects on boll number. The contamination rate at 9-lf, FB, or FB + 2 wk had the greatest effect across locations, reducing the number of bolls per plant when compared to the NTC, with no effect when applied at FB + 4 wk or later. A reduction of boll number was not detectable with the drift rate except in group III when applied at the FB stage. Yield was influenced by 2,4-D rate and stage of cotton growth. Over all locations, loss in yield of greater than 20% occurred at 5 of 12 locations when the drift rate was applied between 4-lf and FB + 2 wk (highest impact at FB). For the contamination rate, yield loss was observed at all 12 locations; averaged over these locations yield loss ranged from 7 to 66% across all growth stages. Results suggest the greatest yield impact from 2,4-D occurs between 9-lf and FB + 2 wk, and the level of impact is influenced by 2,4-D rate, crop growth stage, and environmental conditions.
In this study, we analyse the statistics of both individual inertial particles and inertial particle pairs in direct numerical simulations of homogeneous isotropic turbulence in the absence of gravity. The effect of the Taylor microscale Reynolds number, $R_{{\it\lambda}}$, on the particle statistics is examined over the largest range to date (from $R_{{\it\lambda}}=88$ to 597), at small, intermediate and large Kolmogorov-scale Stokes numbers $St$. We first explore the effect of preferential sampling on the single-particle statistics and find that low-$St$ inertial particles are ejected from both vortex tubes and vortex sheets (the latter becoming increasingly prevalent at higher Reynolds numbers) and preferentially accumulate in regions of irrotational dissipation. We use this understanding of preferential sampling to provide a physical explanation for many of the trends in the particle velocity gradients, kinetic energies and accelerations at low $St$, which are well represented by the model of Chun et al. (J. Fluid Mech., vol. 536, 2005, pp. 219–251). As $St$ increases, inertial filtering effects become more important, causing the particle kinetic energies and accelerations to decrease. The effect of inertial filtering on the particle kinetic energies and accelerations diminishes with increasing Reynolds number and is well captured by the models of Abrahamson (Chem. Engng Sci., vol. 30, 1975, pp. 1371–1379) and Zaichik & Alipchenkov (Intl J. Multiphase Flow, vol. 34 (9), 2008, pp. 865–868), respectively. We then consider particle-pair statistics, and focus our attention on the relative velocities and radial distribution functions (RDFs) of the particles, with the aim of understanding the underlying physical mechanisms contributing to particle collisions. The relative velocity statistics indicate that preferential sampling effects are important for $St\lesssim 0.1$ and that path-history/non-local effects become increasingly important for $St\gtrsim 0.2$. While higher-order relative velocity statistics are influenced by the increased intermittency of the turbulence at high Reynolds numbers, the lower-order relative velocity statistics are only weakly sensitive to changes in Reynolds number at low $St$. The Reynolds-number trends in these quantities at intermediate and large $St$ are explained based on the influence of the available flow scales on the path-history and inertial filtering effects. We find that the RDFs peak near $St$ of order unity, that they exhibit power-law scaling for low and intermediate $St$ and that they are largely independent of Reynolds number for low and intermediate $St$. We use the model of Zaichik & Alipchenkov (New J. Phys., vol. 11, 2009, 103018) to explain the physical mechanisms responsible for these trends, and find that this model is able to capture the quantitative behaviour of the RDFs extremely well when direct numerical simulation data for the structure functions are specified, in agreement with Bragg & Collins (New J. Phys., vol. 16, 2014a, 055013). We also observe that at large $St$, changes in the RDF are related to changes in the scaling exponents of the relative velocity variances. The particle collision kernel closely matches that computed by Rosa et al. (New J. Phys., vol. 15, 2013, 045032) and is found to be largely insensitive to the flow Reynolds number. This suggests that relatively low-Reynolds-number simulations may be able to capture much of the relevant physics of droplet collisions and growth in the adiabatic cores of atmospheric clouds.
In Part 1 of this study (Ireland et al., J. Fluid Mech., vol. 796, 2016, pp. 617–658), we analysed the motion of inertial particles in isotropic turbulence in the absence of gravity using direct numerical simulation (DNS). Here, in Part 2, we introduce gravity and study its effect on single-particle and particle-pair dynamics over a wide range of flow Reynolds numbers, Froude numbers and particle Stokes numbers. The overall goal of this study is to explore the mechanisms affecting particle collisions, and to thereby improve our understanding of droplet interactions in atmospheric clouds. We find that the dynamics of heavy particles falling under gravity can be artificially influenced by the finite domain size and the periodic boundary conditions, and we therefore perform our simulations on larger domains to reduce these effects. We first study single-particle statistics that influence the relative positions and velocities of inertial particles. We see that gravity causes particles to sample the flow more uniformly and reduces the time particles can spend interacting with the underlying turbulence. We also find that gravity tends to increase inertial particle accelerations, and we introduce a model to explain that effect. We then analyse the particle relative velocities and radial distribution functions (RDFs), which are generally seen to be independent of Reynolds number for low and moderate Kolmogorov-scale Stokes numbers $St$. We see that gravity causes particle relative velocities to decrease by reducing the degree of preferential sampling and the importance of path-history interactions, and that the relative velocities have higher scaling exponents with gravity. We observe that gravity has a non-trivial effect on clustering, acting to decrease clustering at low $St$ and to increase clustering at high $St$. By considering the effect of gravity on the clustering mechanisms described in the theory of Zaichik & Alipchenkov (New J. Phys., vol. 11, 2009, 103018), we provide an explanation for this non-trivial effect of gravity. We also show that when the effects of gravity are accounted for in the theory of Zaichik & Alipchenkov (2009), the results compare favourably with DNS. The relative velocities and RDFs exhibit considerable anisotropy at small separations, and this anisotropy is quantified using spherical harmonic functions. We use the relative velocities and the RDFs to compute the particle collision kernels, and find that the collision kernel remains as it was for the case without gravity, namely nearly independent of Reynolds number for low and moderate $St$. We conclude by discussing practical implications of the results for the cloud physics and turbulence communities and by suggesting possible avenues for future research.