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Case 65 - Acquired cholesteatoma

Published online by Cambridge University Press:  18 December 2013

Nafi Aygun
Affiliation:
The Johns Hopkins University
Gaurang Shah
Affiliation:
University of Michigan Health System
Dheeraj Gandhi
Affiliation:
University of Maryland Medical Center
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Summary

Imaging description

Cholesteatoma is a unique, mass-like, destructive and expansile soft tissue lesion of the middle ear, which is a sequela of the reparative process of a perforated tympanic membrane. The stratified squamous epithelial tissue, while attempting to heal the perforation, leads to a ball of exfoliated keratin material surrounded by granulation tissue with lytic enzymes [1].

Pars flaccida cholesteatoma is considered primary cholesteatoma. It begins in the posterosuperior portion of the tympanic membrane, which is more susceptible to infections, and is situated superior to the lateral process of malleus. Pars flaccida accounts for about 80% of all acquired cholesteatomas. It is usually seen in Prussak’s space, associated with blunting of scutum, and extends medially to the posterior part of epitympanum and mesotympanum (Fig. 65.1).

Pars tensa cholesteatoma accounts for 10–20% of all acquired middle ear cholesteatomas and is considered secondary acquired cholesteatoma. It is generally seen in relation to the lower two-thirds of the tympanic membrane, at the site of perforation or retraction pocket at the pars tensa portion of the tympanic membrane. It is seen as a soft tissue mass in the posterior mesotympanum, situated medial to the ossicles, and may involve the region of sinus tympani, facial nerve recess, and aditus ad antrum (Fig. 65.2). Erosion of auditory ossicles, especially the long process of incus and superstructure of stapes, is common. It is locally aggressive, and erosion of the adjoining bony structures and auditory ossicles is both characteristic and diagnostic [2].

Type
Chapter
Information
Pearls and Pitfalls in Head and Neck and Neuroimaging
Variants and Other Difficult Diagnoses
, pp. 299 - 303
Publisher: Cambridge University Press
Print publication year: 2013

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References

Karmody, CS, Northrop, C. The pathogenesis of acquired cholesteatoma of the human middle ear: support for the migration hypothesis. Otol Neurotol 2012; 33: 42–7.CrossRefGoogle ScholarPubMed
Lemmerling, MM, De Foer, B, Verbist, BM, VandeVyver, V. Imaging of inflammatory and infectious diseases in the temporal bone. Neuroimaging Clin N Am 2009; 19: 321–37.CrossRefGoogle ScholarPubMed
Yamashita, K, Yoshiura, T, Hiwatashi, A, et al. Detection of middle ear cholesteatoma by diffusion-weighted MR imaging: multishot echo-planar imaging compared with single-shot echo-planar imaging. AJNR Am J Neuroradiol 2011; 32: 1915–18.CrossRefGoogle ScholarPubMed

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