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Hypoglycemia

from Section 3 - Classic and rare scenarios in the neonatal period

Published online by Cambridge University Press:  05 March 2012

Tilman Humpl
Affiliation:
Hospital for Sick Children, Toronto
Georg Hansmann
Affiliation:
Children's Hospital Boston, Harvard Medical School
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Summary

Definition

Hypoglycemia in neonates is a relatively common, heterogenous and potentially serious problem. A consistent definition of hypoglycemia does not exist in the literature or in clinical practice.

Epidemiology

  • Hypoglycemia is a frequent concern in neonatology

  • For the majority of healthy term infants, low glucose levels reflect metabolic adaptation to extrauterine life

  • If the first feeding is delayed by 3–6 h, 10% of healthy neonates are not able to maintain their blood glucose level above 30 mg/dl (1.7 mmol/l). After 12 h of life (and feeding) the risk for symptomatic hypoglycemia declines, but still exists for the term infant with low birth weight (<2500 g; SGA), with high birth weight (LGA), and postasphyxic newborns.

Diagnosis

The diagnosis of hypoglycemia may be made in the symptomatic neonate with a low blood glucose concentration and resolving symptoms after normalization of the blood glucose concentration. Transient hypoglycemia in the first few hours after birth is relatively frequent. Hypoglycemia that is persistent requires further investigation.

WHO guidelines – hypoglycemia of the newborn (continued on p. 262)

• Healthy term newborns who are breastfeeding on demand do not need to have their blood glucose routinely checked and need no supplementary foods or fluids

• Healthy term newborns do not develop “symptomatic” hypoglycemia as a result of simple underfeeding. If an infant develops signs suggesting hypoglycemia, look for an underlying cause. This usually means drawing a blood sample (serum tube, better: sodium fluoride tube) at the time of hypoglycemia prior to treatment. Detection of the cause is as important as immediate correction of the blood glucose level

• Thermal protection (the maintenance of normal body temperature) in addition to breastfeeding is necessary to prevent hypoglycemia […]

Type
Chapter
Information
Neonatal Emergencies , pp. 260 - 268
Publisher: Cambridge University Press
Print publication year: 2009

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  • Hypoglycemia
  • Edited by Georg Hansmann
  • Book: Neonatal Emergencies
  • Online publication: 05 March 2012
  • Chapter DOI: https://doi.org/10.1017/CBO9781139010467.047
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  • Hypoglycemia
  • Edited by Georg Hansmann
  • Book: Neonatal Emergencies
  • Online publication: 05 March 2012
  • Chapter DOI: https://doi.org/10.1017/CBO9781139010467.047
Available formats
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Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Hypoglycemia
  • Edited by Georg Hansmann
  • Book: Neonatal Emergencies
  • Online publication: 05 March 2012
  • Chapter DOI: https://doi.org/10.1017/CBO9781139010467.047
Available formats
×