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Chap 9 - BENIGN FIBROBLASTIC AND MYOFIBROBLASTIC PROLIFERATIONS IN CHILDREN

Published online by Cambridge University Press:  01 March 2011

Markku Miettinen
Affiliation:
Armed Forces Institute of Pathology, Washington DC
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Summary

Benign fibroblastic proliferations typical of children have here been divided into three categories: fasciitis and pseudotumors, fibromas and fibromatoses, and other benign fibrous proliferations. Among these are included a total of fifteen different clinicopathologic entities, which will be discussed here. These entities span a wide clinicopathologic and morphologic spectrum from non-neoplastic to neoplastic, with some examples of indeterminate conditions. Common to them all, however, is the potential for recurrence only, and none for metastasis. Some of these conditions can also occur in adults (e.g., calcifying fibrous tumor, calcifying aponeurotic fibroma, myofibroma). Conversely, many fibrous proliferations typically seen in adults also occur in children (e.g., nodular fasciitis, palmar, plantar and desmoid fibromatoses) – these are discussed in Chapter 8. Fibroblastic and myofibroblastic lesions of childhood with variable biologic potential are discussed in Chapter 10. Desmoid tumor is discussed in Chapter 8.

The terminology of some childhood fibrous tumors does not match the lesion type: some names are clearly misnomers and probably will be adjusted in the future. For example, the term fibromatosis has been historically applied to purely reactive, reparative processes such as fibromatosis colli, in addition to their main use for lesions with recurrence potential, such as desmoid. Similarly, some conditions classified as fibromas might be closer to fibromatosis in some respects. For example, calcifying aponeurotic fibroma tends to have diffuse infiltrative borders and significant potential for recurrence.

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Chapter
Information
Modern Soft Tissue Pathology
Tumors and Non-Neoplastic Conditions
, pp. 255 - 284
Publisher: Cambridge University Press
Print publication year: 2010

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References

Lauer, DH, Enzinger, FM. Cranial fasciitis in childhood. Cancer 1980;45:401–406.3.0.CO;2-C>CrossRefGoogle ScholarPubMed
Patterson, JW, Moran, SL, Konerding, H. Cranial fasciitis. Arch Dermatol 1989;125:674–678.CrossRefGoogle ScholarPubMed
Sarangarajan, R, Dehner, LP. Cranial and extracranial fasciitis of childhood: a clinicopathologic and immunohistochemical study. Hum Pathol 1999;30:87–92.CrossRefGoogle ScholarPubMed
Rapana, A, Iaccarino, C, Bellotti, A, Marsicano, C, Donnianni, T, Tedeschi, E. Exclusively intracranial and cranial fasciitis of the adult age. Clin Neurol Neurosurg 2002;105:35–38.CrossRefGoogle ScholarPubMed
Sayama, T, Morioka, T, Baba, T, Ikezaki, K, Fukui, M. Cranial fasciitis with massive intracranial extension. Childs Nerve Syst 1995;11:242–245.CrossRefGoogle ScholarPubMed
MacDonald, D. Sternomastoid tumor and muscular torticollis. J Bone Joint Surg [Br] 1969;51:432–443.CrossRefGoogle ScholarPubMed
Wakely, Pe Jr, Price, WG, Frable, WJ. Sternomastoid tumor of infancy (fibromatosis colli): diagnosis by aspiration cytology. Mod Pathol 1989;2:378–381.Google ScholarPubMed
Sauer, F, Sehner, L, Freng, A. Cytologic features of fibromatosis colli of infancy. Acta Cytol 1997;41:633–635.CrossRefGoogle ScholarPubMed
Vargas, SO. Fibrous umbilical polyp: a distinct fasciitis-like proliferation of early childhood with a marked male predominance. Am J Surg Pathol 2001;25:1438–1442.CrossRefGoogle ScholarPubMed
Clark, D. Gingival fibromatosis and its related syndromes: A review. J Can Dent Assoc 1987;53:137–140.Google ScholarPubMed
Coletta, RD, Graner, E. Hereditary gingival fibromatosis: A systematic review. J Periodontol 2006;77:753–766.CrossRefGoogle ScholarPubMed
Doufexi, A, Mina, M, Ioannidou, E. Gingival overgrowth in children: epidemiology, pathogenesis, and complications: A literature review. J Periodontol 2005;76:3–10.CrossRefGoogle ScholarPubMed
Hart, TC, Pallos, D, Bozzo, L, Almeida, OP, Marazita, ML, O'Connell, JR. Evidence of genetic heterogeneity for hereditary gingival fibromatosis. J Dent Res 2000;79:1758–1764.CrossRefGoogle ScholarPubMed
Bitu, CC, Sobral, LM, Kellermann, MG, Martelli-Junior, H, Zecchin, KG, Graner, E. Heterogeneous presence of myofibroblasts in hereditary gingival fibromatosis. J Clin Periodontol 2006;33:393–400.CrossRefGoogle ScholarPubMed
Hart, TC, Zhang, Y, Gorry, MC, Hart, S, Cooper, M, Marazita, ML. A mutation in the SOS1 gene causes hereditary gingival fibromatosis. Am J Hum Genet 2002;70:943–954.CrossRefGoogle ScholarPubMed
Xiao, S, Bu, L, Zhu, L, Zheng, G, Yang, M, Qian, M. A new locus for hereditary gingival fibromatosis (GINGF2) maps to 5q13–q22. Genomics 2001;74:180–185.CrossRefGoogle ScholarPubMed
Rosenthal, NS, Abdul-Karim, FW. Childhood fibrous tumor with psammoma bodies. Clinicopathologic features in two cases. Arch Pathol Lab Med 1988;112:798–800.Google Scholar
Fetsch, JF, Montgomery, EA, Meis, JM. Calcifying fibrous pseudotumor. Am J Surg Pathol 1993;17:502–508.CrossRefGoogle ScholarPubMed
Fletcher, CD, Mertens, F, Unni, KK. WHO classification of tumours. Pathology and Genetics: Tumours of Soft Tissue and Bone. Lyon: IRC Press, 2002.Google Scholar
Nascimento, AF, Ruiz, R, Hornick, JL, Fletcher, CD. Calcifying fibrous ‘pseudotumor’: clinicopathologic study of 15 cases and analysis of its relationship to inflammatory myofibroblastic tumor. Int J Surg Pathol 2002;10:189–196.CrossRefGoogle ScholarPubMed
Pinkard, NB, Wilson, RW, Lawless, N, Dodd, LG, McAdams, HP, Koss, MN. Calcifying fibrous pseudotumor of pleura. A report of three cases of a newly described entity involving the pleura. Am J Clin Pathol 1996;105:189–94.CrossRefGoogle ScholarPubMed
Hainaut, P, Lesage, V, Weynand, B, Coche, E, Noirhomme, P. Calcifying fibrous pseudotumor (CFPT): a patient presenting with multiple pleural lesions. Acta Clin Belg 1999;54:162–164.CrossRefGoogle ScholarPubMed
Kocova, L, Michal, M, Sulc, M, Zamecnik, M. Calcifying fibrous pseudotumour of visceral peritoneum. Histopathology 1997;31:181–184.CrossRefGoogle ScholarPubMed
Soyer, T, Ciftci, AO, Gucer, S, Orhan, D, Senocak, ME. Calcifying fibrous pseudotumor of lung: a previously unreported entity. J Pediatr Surg 2004;39:1729–1730.CrossRefGoogle ScholarPubMed
Dumont, P, Muret, A, Skrobala, D, Robin, P, Toumieux, B. Calcifying fibrous pseudotumor of the mediastinum. Ann Thorac Surg 1997;63:543–544.CrossRefGoogle ScholarPubMed
Chon, SH, Lee, CB, Oh, YH. Calcifying fibrous pseudotumor causing thoracic outlet syndrome. Eur J Cardiothorac Surg 2005;27:353–355.CrossRefGoogle ScholarPubMed
Maeda, A, Kawabata, K, Kusuzaki, K. Rapid recurrence of calcifying fibrous pseudotumor (a case report). Anticancer Res 2002;22:1795–1797.Google Scholar
Ben-Izhak, O, Itin, L, Feuchtwanger, Z, Lifschitz-Mercer, B, Czernobilsky, B. Calcifying fibrous pseudotumor of mesentery presenting with acute peritonitis: case report with immunohistochemical study and review of literature. Int J Surg Pathol 2001;9:249–253.CrossRefGoogle ScholarPubMed
Sigel, JE, Smith, TA, Reith, JD, Goldblum, JR. Immunohistochemical analysis of anaplastic lymphoma kinase expression in deep soft tissue calcifying fibrous pseudotumor: evidence of a late sclerosing stage of inflammatory myofibroblastic tumor?Ann Diagn Pathol 2001;5:10–14.CrossRefGoogle ScholarPubMed
Hill, KA, Gonzalez-Crussi, F, Chou, PM. Calcifying fibrous pseudotumor versus inflammatory myofibroblastic tumor: a histological and immunohistochemical comparison. Mod Pathol 2001;14:784–790.CrossRefGoogle ScholarPubMed
Dorpe, J, Ectors, N, Geboes, K, D'Hoore, A, Sciot, R. Is calcifying fibrous pseudotumor a late sclerosing stage of inflammatory myofibroblastic tumor?Am J Surg Pathol 1999;23:329–335.CrossRefGoogle ScholarPubMed
Reye, RDK. Recurring digital fibrous tumor of childhood. Arch Pathol 1965;80:228–23.Google ScholarPubMed
Allen, PW. Recurring digital fibrous tumor of childhood. Pathology 1972;4:215–223.CrossRefGoogle ScholarPubMed
Beckett, JH, Jacobs, AH. Recurring digital fibrous tumor of childhood: a review. Pediatrics 1977;59:401–406.Google ScholarPubMed
Santa-Cruz, DJ, Reiner, CB. Recurrent digital fibroma of childhood. J Cutan Pathol 1978;5:339–346.CrossRefGoogle ScholarPubMed
Bhawan, J, Bacchetta, C, Joris, I, Majno, G. A myofibroblastic tumor. Infantile digital fibroma (recurrent digital fibrous tumor of childhood). Am J Pathol 1979;94:19–36.Google Scholar
Ishii, N, Matsui, K, Ichiyama, S, Takahashi, Y, Nakajima, H. A case of infantile digital fibromatosis showing spontaneous regression. Br J Dermatol 1989;121:129–133.CrossRefGoogle ScholarPubMed
Rimareix, F, Bardot, J, Anmdrac, L, Vasse, D, Galinier, P, Magalon, G. Infantile digital fibroma – report on eleven cases. Eur J Pediatr Surg 1997;7:345–348.CrossRefGoogle ScholarPubMed
Laskin, WB, Miettinen, M, Fetsch, JF. Infantile digital fibroma/fibromatosis: a clinicopathological and immunohistochemical study of 69 tumors from 57 patients with long-term follow-up. Am J Surg Pathol 2009; 33:1–13.CrossRefGoogle Scholar
Breuning, MH, Oranje, AP, Langemeijer, RA, Hovius, SE, Diepstraten, AF, Hollander, JC. Recurrent digital fibroma, focal dermal hypoplasia, and limb malformations. Am J Med Genet 2000;94:91–101.3.0.CO;2-D>CrossRefGoogle ScholarPubMed
Iwasaki, H, Kikuchi, M, Ohtsuki, I, Enjoji, M, Suenaga, N, Mori, R. Infantile digital fibromatosis. Identification of actin filaments in cytoplasmic inclusions by heavy meromyosin binding. Cancer 1983;52:1653–1661.3.0.CO;2-C>CrossRefGoogle ScholarPubMed
Fringer, B, Thais, H, Bohm, N, Altmannsberger, M, Osborn, M. Identification of actin microfilaments in the intracytoplasmic inclusions present in recurring infantile digital fibromatosis (Reye tumor). Pediatr Pathol 1986;6:311–324.CrossRefGoogle Scholar
Mukai, M, Torikata, C, Iri, H, Hata, J, Naito, M, Shimoda, T. Immunohistochemical identification of aggregated actin filaments in formalin-fixed, paraffin-embedded sections, I. A study of infantile digital fibromatosis by a new pretreatment. Am J Surg Pathol 1992;16:110–115.CrossRefGoogle ScholarPubMed
Hyashi, T, Tsuda, N, Chowdhury, PR, Anami, M, Kishikawa, M, Iseki, M. Infantile digital fibromatosis: a study of the development and regression of cytoplasmic inclusion bodies. Mod Pathol 1995;8:548–552.Google Scholar
Sarma, DP, Hoffmann, EO. Infantile digital fibroma-like tumor in an adult. Arch Dermatol 1980;116:578–579.CrossRefGoogle Scholar
Viale, G, Doglioni, C, Iuzzolino, P, Bontempini, L, Colombi, R, Coggi, G. Infantile digital fibromatosis-like tumour (inclusion body fibromatosis) of adulthood: report of two cases with ultrastructural and immunocytochemical findings. Histopathology 1988;12:415–424.CrossRefGoogle ScholarPubMed
Bittesini, L, DeiTos, AP, Doglioni, C, DellaLibera, D, Laurino, L, Fletcher, CD. Fibro-epithelial tumor of the breast with digital fibroma-like inclusions in the stromal component. Case report with immunocytochemical and ultrastructural analysis. Am J Surg Pathol 1994;18:296–301.CrossRefGoogle Scholar
Hiraoka, N, Mukai, M, Hosoda, Y, Hata, J. Phyllodes tumor of the breast containing the intracytoplasmic inclusion bodies identical with infantile digital fibromatosis. Am J Surg Pathol 1994;18:506–511.CrossRefGoogle ScholarPubMed
Navas-Palacios, JJ, Conde-Zurita, JM. Inclusion body myofibroblasts other than those seen in recurrent digital fibroma of childhood. Ultrastruct Pathol 1984;7:109–121.CrossRefGoogle Scholar
Keasbey, . Juvenile aponeurotic fibroma (calcifying fibroma): A distinctive tumor arising in the palms and soles of young children. Calcifying aponeurotic fibroma. Cancer 1953;6:338–346.3.0.CO;2-M>CrossRefGoogle Scholar
Goldman, RL. The cartilage analogy of fibromatosis (aponeurotic fibroma): further observations based on seven new cases. Cancer 1970;26:1325–1331.3.0.CO;2-M>CrossRefGoogle Scholar
Allen, PW, Enzinger, FM. Juvenile aponeurotic fibroma. Cancer 1970;26:857–867.3.0.CO;2-S>CrossRefGoogle ScholarPubMed
Fetsch, JF, Miettinen, M. Calcifying aponeurotic fibroma: a clinicopathologic study of 22 cases arising in uncommon sites. Hum Pathol 1998;29:1504–1510.CrossRefGoogle ScholarPubMed
Fetsch, JF, Miettinen, M, Laskin, WB, Michal, M, Enzinger, FM. A clinicopathologic study of 45 pediatric soft tissue tumors with an admixture of adipose tissue and fibroblastic elements, and a proposal for classification as lipofibromatosis. Am J Surg Pathol 2000;24:1491–1500.CrossRefGoogle Scholar
Herrmann, BW, Dehner, LP, Forsen, JW. Lipofibromatosis presenting as a pediatric neck mass. Int J Pediatr Otolaryngol 2004;68:1545–1549.CrossRefGoogle ScholarPubMed
Sasaki, D, Hatori, M, Hosaka, M, Watanabe, M, Kokubun, S. Lipofibromatosis arising in a pediatric forearm – a case report. Ups J Med Sci 2005;110:259–266.CrossRefGoogle Scholar
Enzinger, FM. Fibrous tumors of infancy. In: Tumors of Bone and Soft Tissue. Chicago, Year Book Medical Publishers, 1965;231–268.Google Scholar
Wehrli, BM, Weiss, SW, Yandow, S. Garner-associated fibromas (GAF) in young patients: a distinct fibrous lesion that identifies unsuspected Garner syndrome and risk for fibromatosis. Am J Surg Pathol 2001;25:645–651.CrossRefGoogle Scholar
Coffin, CM, Hornick, JL, Zhou, H, Fletcher, CDM. Gardner fibroma: A clinicopathologic and immunohistochemical analysis of 45 patients with 57 fibromas. Am J Surg Pathol 2006;31:410–416.CrossRefGoogle Scholar
Michal, M, Boudova, L, Mukensnabl, P. Gardner's syndrome associated fibromas. Pathol Int 2004;54:523–526.CrossRefGoogle ScholarPubMed
Diwan, AH, Graves, ED, King, JA, Horenstein, MG. Nuchal-type fibroma in two related patients with Gardner's syndrome. Am J Surg Pathol 2000;24:1563–1567.CrossRefGoogle ScholarPubMed
Sternberg, SS. Pathology of juvenile nasopharyngeal angiofibroma; a lesion of adolescent males. Cancer 1954;7:15–28.3.0.CO;2-I>CrossRefGoogle ScholarPubMed
Neel, HB 3rd, Whicker, JH, Devine, KD, Weiland, LH. Juvenile angiofibroma: Review of 120 cases. Am J Surg 1973;126:547–556.CrossRefGoogle ScholarPubMed
Witt, TR, Shah, JP, Sternberg, SS. Juvenile nasopharyngeal angiofibroma: A 30-year clinical review. Am J Surg 1983;146:521–525.CrossRefGoogle ScholarPubMed
Economou, TS, Abemayor, E, Ward, PH. Juvenile nasopharyngeal angiofibroma: an update of the UCLA experience, 1960–1985. Laryngoscope 1988;98:170–175.CrossRefGoogle ScholarPubMed
Ungkanont, K, Byers, RM, Weber, RS, Callender, DL, Wolf, PF, Goepfert, H. Juvenile nasopharyngeal angiofibroma: an update of therapeutic management. Head Neck 1996;18:60–66.3.0.CO;2-X>CrossRefGoogle ScholarPubMed
Enepekides, DJ. Recent advances in the treatment of juvenile angiofibroma. Curr Opin Otolaryngol Head Neck Surg 2004;12:495–499.CrossRefGoogle ScholarPubMed
Onerci, M, Ogretmenoglu, O, Yucel, T. Juvenile nasopharyngeal angiofibroma: a revised staging system. Rhinology 2006;44:39–45.Google ScholarPubMed
Yadav, SP, Singh, I, Chanda, R, Sachdeva, OP. Nasopharyngeal angiofibroma. J Otolaryngol 2002;31:346–350.CrossRefGoogle ScholarPubMed
Giardiello, FM, Hamilton, SR, Krush, AJ, Offerhaus, JA, Booker, SV, Petersen, GM. Nasopharyngeal angiofibroma in patients with familial adenomatous polyposis. Gastroenterology 1993;105:1550–1552.CrossRefGoogle ScholarPubMed
Batsakis, JG, Klopp, CT, Newman, W. Fibrosarcoma arising in a juvenile nasopharyngeal angiofibroma following extensive radiation therapy. Am Surg 1955;21:786–793.Google Scholar
Chen, KT, Bauer, FW. Sarcomatous transformation of nasopharyngeal angiofibroma. Cancer 1982;49:369–371.3.0.CO;2-Y>CrossRefGoogle ScholarPubMed
Spagnolo, DV, Papadimitriou, JM, Archer, M. Postirradiation malignant fibrous histiocytoma arising in juvenile nasopharyngeal angiofibroma and producing alpha-1-antitrypsin. Histopathology 1984;8:339–352.CrossRefGoogle ScholarPubMed
Makek, MS, Andrews, JC, Fisch, U. Malignant transformation of a nasopharyngeal angiofibroma. Laryngoscope 1989;99(10 Pt 1):1088–1092.CrossRefGoogle ScholarPubMed
Beham, A, Fletcher, CD, Kainz, J, Schmid, C, Humer, U. Nasopharyngeal angiofibroma: an immunohistochemical study of 32 cases. Virchows Arch A Pathol Anat Histopathol 1993;423:281–285.CrossRefGoogle ScholarPubMed
Beham, A, Kainz, J, Stammberger, H, Aubock, L, Beham-Schmid, C. Immunohistochemical and electron microscopical characterization of stromal cells in nasopharyngeal angiofibromas. Eur Arch Otorhinolaryngol 1997;254:196–199.CrossRefGoogle ScholarPubMed
Abraham, SC, Montgomery, EA, Giardiello, FM, Wu, TT. Frequent beta-catenin mutations in juvenile nasopharyngeal angiofibromas. Am J Pathol 2001;158:1073–1078.CrossRefGoogle ScholarPubMed
Hwang, HC, Mills, SE, Patterson, K, Gown, AM. Expression of androgen receptors in nasopharyngeal angiofibroma: an immunohistochemical study of 24 cases. Mod Pathol 1998;11:1122–1126.Google ScholarPubMed
Zhang, PJ, Weber, R, Liang, HH, Pasha, TL, LiVolsi, VA. Growth factors and receptors in juvenile nasopharyngeal angiofibroma and nasal polyps: an immunohistochemical study. Arch Pathol Lab Med 2003;127:1480–1484.Google Scholar
Montag, AG, Tretiakova, M, Richardson, M. Steroid hormone receptor expression in nasopharyngeal angiofibromas. Am J Clin Pathol 2006;125:832–837.CrossRefGoogle ScholarPubMed
Enzinger, FM. Fibrous hamartoma of infancy. Cancer 1965;18:241–248.3.0.CO;2-C>CrossRefGoogle ScholarPubMed
Efem, SE, Ekpo, MD. Clinicopathological features of untreated fibrous hamartoma of infancy. J Clin Pathol 1993;46:522–524.CrossRefGoogle ScholarPubMed
Popek, EJ, Montgomery, EA, Fourcroy, JL. Fibrous hamartoma of infancy in the genital region: findings in 15 cases. J Urol 1994;151:990–993.CrossRefGoogle Scholar
Sotelo-Avila, C, Bale, PM. Subdermal fibrous hamartoma of infancy: pathology of 40 cases and differential diagnosis. Pediatr Pathol 1994;14:39–52.CrossRefGoogle ScholarPubMed
Dickey, GE, Sotelo-Avila, C. Fibrous hamartoma of infancy: Current review. Pediatr Dev Pathol 1999;2:236–243.CrossRefGoogle ScholarPubMed
Michal, M, Mukensnabl, P, Chlumska, A, Kodet, R. Fibrous hamartoma of infancy: A study of eight cases with immunohistochemical and electron microscopic findings. Pathol Res Pract 1992;188:1049–1053.CrossRefGoogle Scholar
Carretto, E, Dall'Igna, P, Alaggio, R, Siracusa, F, Granata, C, Ferrari, A. Fibrous hamartoma of infancy: an Italian multi-institutional experience. J Am Acad Dermatol 2006;54:800–803.CrossRefGoogle ScholarPubMed
Lakshminarayanan, R, Konia, T, Welborn, J. Fibrous hamartoma of infancy: a case report with associated cytogenetic findings. Arch Pathol Lab Med 2005;129:520–522.Google ScholarPubMed
Chung, EB, Enzinger, FM. Infantile myofibromatosis: A review of 59 cases with localized and generalized involvement. Cancer 1981;48:1807–1818.3.0.CO;2-G>CrossRefGoogle Scholar
Briselli, MF, Soule, EH, Gilchrist, GS. Congenital fibromatosis. Report of 18 cases of solitary and 4 cases of multiple tumors. Mayo Clin Proc 1980;55:554–562.Google ScholarPubMed
Daimaru, Y, Hashimoto, H, Enjoji, M. Myofibromatosis in adults (adult counterpart of infantile myofibromatosis). Am J Surg Pathol 1989;13:859–865.CrossRefGoogle Scholar
Smith, KJ, Skelton, HG, Barrett, TL, Lupton, GP, Graham, JH. Cutaneous myofibroma. Mod Pathol 1989;2:603–609.Google ScholarPubMed
Foss, RD, Ellis, GL. Myofibromas and myofibromatosis of the oral region: A clinicopathologic analysis of 79 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;89:57–65.CrossRefGoogle ScholarPubMed
Jennings, T, Duray, PH, Collins, FS. Infantile myofibromatosis. Evidence for an autosomal-dominant disorder. Am J Surg Pathol 1984;8:529–538.CrossRefGoogle ScholarPubMed
Wiswell, TE, Davis, J, Cunningham, BE, Solenberger, L, Thomas, PJ. Infantile myofibromatosis: the most common fibrous tumor of infancy. J Pediatr Surg 1988;23:315–318.CrossRefGoogle ScholarPubMed
Coffin, CM, Neilson, KA, Ingels, S, Frank-Gerszberg, R, Dehner, LP. Congenital generalized fibromatosis: a disseminated angiocentric myofibromatosis. Pediatr Pathol Lab Med 1995;15:571–587.CrossRefGoogle Scholar
Fukasawa, Y, Ishikura, H, Takada, A, Yokoyama, S, Imamura, M, Yoshiki, T. Massive apoptosis in infantile myofibromatosis. A putative mechanism for tumor regression. Am J Pathol 1995;144:480–485.Google Scholar
Stenman, G, Nadal, N, Persson, S, Gunterberg, B, Angervall, L. del(6)(q12q15) as the sole cytogenetic abnormality in a case of solitary infantile myofibromatosis. Oncol Rep 1999;6:1101–1104.Google Scholar
Mentzel, T, Calonje, E, Nascimento, AG, Fletcher, CDM. Infantile hemangiopericytoma versus infantile myofibromatosis: Study of a series suggesting a continuous spectrum of infantile myofibroblastic lesions. Am J Surg Pathol 1994;18:922–930.CrossRefGoogle ScholarPubMed
Kitano, Y, Horiki, M, Aoki, T, Sagami, S. Two cases of juvenile hyaline fibromatosis. Some histological, electron microscopic, and tissue culture observations. Arch Dermatol 1972;106:877–883.CrossRefGoogle Scholar
Ishikawa, H, Mori, S. Systemic hyalinosis or fibromatosis hyalinica multiplex juvenilis as a congenital syndrome. A new entity based on the inborn error of acid mucopolysaccharide metabolism in connective tissue cells?Acta Derm Venereol 1973;53:185–191.Google ScholarPubMed
Remberger, K, Krieg, T, Kunze, D, Weinmann, HM, Hubner, G. Fibromatosis hyalinica multiplex (juvenile hyalin fibromatosis). Light microscopic, electron microscopic, immunohistochemical, and biochemical findings. Cancer 1985;56:614–624.3.0.CO;2-T>CrossRefGoogle ScholarPubMed
Fayad, MN, Yacoub, A, Salman, S, Khudr, A, Kaloustian, VM. Juvenile hyaline fibromatosis: two new patients and review of the literature. Am J Med Genet 1987;26:123–131.CrossRefGoogle ScholarPubMed
Mancini, GM, Stojanov, L, Willemsen, R, Kleijer, WJ, Huijmans, JG, Diggelen, OP. Juvenile hyaline fibromatosis: clinical heterogeneity in three patients. Dermatology 1999;198:18–25.CrossRefGoogle ScholarPubMed
Senzaki, H, Kiyozuka, Y, Uemura, Y, Shikata, N, Ueda, S, Tsubura, A. Juvenile hyaline fibromatosis: a report of two unrelated adult sibling cases and a literature review. Pathol Int 1998;48:230–236.CrossRefGoogle Scholar
Haleem, A, Al-Hindi, HN, Joboury, MA, Husseini, HA, Ajlan, AA. Juvenile hyaline fibromatosis: morphologic, immunohistochemical, and ultrastructural study of three siblings. Am J Dermatopathol 2002;24:218–224.CrossRefGoogle ScholarPubMed
Landing, BH, Nadorra, R. Infantile systemic hyalinosis: report of four cases of a disease, fatal in infancy, apparently different from juvenile systemic hyalinosis. Pediatr Pathol 1986;6:55–79.CrossRefGoogle ScholarPubMed
Dowling, O, Difeo, A, Ramirez, MC, Tukel, T, Narla, G, Bonafe, L. Mutations in capillary morphogenesis gene-2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis. Am J Hum Genet 2003;73:957–966.CrossRefGoogle ScholarPubMed
Hanks, S, Adams, S, Douglas, J, Arbour, L, Atherton, DJ, Balci, S. Mutations in the gene encoding capillary morphogenesis protein 2 cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Am J Hum Genet 2003;73:791–800.CrossRefGoogle ScholarPubMed
Wiedemann, HR, Burgio, GR, Aldenhoff, P, Kunze, J, Kaufmann, HJ, Schilg, E. The proteus syndrome. Partial gigantism of the hands and/or feet, nevi, hemihypertrophy, subcutaneous tumors, macroceophaly, or other skull anomalies, and possible accelerated growth and visceral affections. Eur J Pediatr 1983;140:5–12.CrossRefGoogle ScholarPubMed
Biesecker, LG, Happle, R, Mulliken, JB, Weksberg, R, Graham, JM Jr, Viljoen, DL. Proteus syndrome: Diagnostic criteria, differential diagnosis, and patient evaluation. Am J Med Genet 1999;84:389–395.3.0.CO;2-O>CrossRefGoogle ScholarPubMed
Nguyen, T, Turner, JT, Olsen, C, Biesecker, LG, Darling, TN. Cutaneous manifestations of Proteus syndrome: correlations with general clinical severity. Arch Dermatol 2004;140:1001–1002.CrossRefGoogle ScholarPubMed
Twede, JV, Turner, JT, Biesecker, LG, Darling, TN. Evolution of skin lesions in Proteus syndrome. J Am Acad Dermatol 2005;52:834–838.CrossRefGoogle ScholarPubMed
Gordon, PL, Wilroy, LS, Lasater, OE, Cohen, MM. Neoplasms in Proteus syndrome. Am J Med Genet 1995;57:74–78.CrossRefGoogle ScholarPubMed
Loffeld, A, McLellan, NJ, Cole, T, Payne, SJ, Fricker, D, Moss, C. Epidermal naevus in Proteus syndrome showing loss of heterozygosity for an inherited PTEN mutation. Br J Dermatol 2006;154:1194–1198.CrossRefGoogle ScholarPubMed
Lauer, DH, Enzinger, FM. Cranial fasciitis in childhood. Cancer 1980;45:401–406.3.0.CO;2-C>CrossRefGoogle ScholarPubMed
Patterson, JW, Moran, SL, Konerding, H. Cranial fasciitis. Arch Dermatol 1989;125:674–678.CrossRefGoogle ScholarPubMed
Sarangarajan, R, Dehner, LP. Cranial and extracranial fasciitis of childhood: a clinicopathologic and immunohistochemical study. Hum Pathol 1999;30:87–92.CrossRefGoogle ScholarPubMed
Rapana, A, Iaccarino, C, Bellotti, A, Marsicano, C, Donnianni, T, Tedeschi, E. Exclusively intracranial and cranial fasciitis of the adult age. Clin Neurol Neurosurg 2002;105:35–38.CrossRefGoogle ScholarPubMed
Sayama, T, Morioka, T, Baba, T, Ikezaki, K, Fukui, M. Cranial fasciitis with massive intracranial extension. Childs Nerve Syst 1995;11:242–245.CrossRefGoogle ScholarPubMed
MacDonald, D. Sternomastoid tumor and muscular torticollis. J Bone Joint Surg [Br] 1969;51:432–443.CrossRefGoogle ScholarPubMed
Wakely, Pe Jr, Price, WG, Frable, WJ. Sternomastoid tumor of infancy (fibromatosis colli): diagnosis by aspiration cytology. Mod Pathol 1989;2:378–381.Google ScholarPubMed
Sauer, F, Sehner, L, Freng, A. Cytologic features of fibromatosis colli of infancy. Acta Cytol 1997;41:633–635.CrossRefGoogle ScholarPubMed
Vargas, SO. Fibrous umbilical polyp: a distinct fasciitis-like proliferation of early childhood with a marked male predominance. Am J Surg Pathol 2001;25:1438–1442.CrossRefGoogle ScholarPubMed
Clark, D. Gingival fibromatosis and its related syndromes: A review. J Can Dent Assoc 1987;53:137–140.Google ScholarPubMed
Coletta, RD, Graner, E. Hereditary gingival fibromatosis: A systematic review. J Periodontol 2006;77:753–766.CrossRefGoogle ScholarPubMed
Doufexi, A, Mina, M, Ioannidou, E. Gingival overgrowth in children: epidemiology, pathogenesis, and complications: A literature review. J Periodontol 2005;76:3–10.CrossRefGoogle ScholarPubMed
Hart, TC, Pallos, D, Bozzo, L, Almeida, OP, Marazita, ML, O'Connell, JR. Evidence of genetic heterogeneity for hereditary gingival fibromatosis. J Dent Res 2000;79:1758–1764.CrossRefGoogle ScholarPubMed
Bitu, CC, Sobral, LM, Kellermann, MG, Martelli-Junior, H, Zecchin, KG, Graner, E. Heterogeneous presence of myofibroblasts in hereditary gingival fibromatosis. J Clin Periodontol 2006;33:393–400.CrossRefGoogle ScholarPubMed
Hart, TC, Zhang, Y, Gorry, MC, Hart, S, Cooper, M, Marazita, ML. A mutation in the SOS1 gene causes hereditary gingival fibromatosis. Am J Hum Genet 2002;70:943–954.CrossRefGoogle ScholarPubMed
Xiao, S, Bu, L, Zhu, L, Zheng, G, Yang, M, Qian, M. A new locus for hereditary gingival fibromatosis (GINGF2) maps to 5q13–q22. Genomics 2001;74:180–185.CrossRefGoogle ScholarPubMed
Rosenthal, NS, Abdul-Karim, FW. Childhood fibrous tumor with psammoma bodies. Clinicopathologic features in two cases. Arch Pathol Lab Med 1988;112:798–800.Google Scholar
Fetsch, JF, Montgomery, EA, Meis, JM. Calcifying fibrous pseudotumor. Am J Surg Pathol 1993;17:502–508.CrossRefGoogle ScholarPubMed
Fletcher, CD, Mertens, F, Unni, KK. WHO classification of tumours. Pathology and Genetics: Tumours of Soft Tissue and Bone. Lyon: IRC Press, 2002.Google Scholar
Nascimento, AF, Ruiz, R, Hornick, JL, Fletcher, CD. Calcifying fibrous ‘pseudotumor’: clinicopathologic study of 15 cases and analysis of its relationship to inflammatory myofibroblastic tumor. Int J Surg Pathol 2002;10:189–196.CrossRefGoogle ScholarPubMed
Pinkard, NB, Wilson, RW, Lawless, N, Dodd, LG, McAdams, HP, Koss, MN. Calcifying fibrous pseudotumor of pleura. A report of three cases of a newly described entity involving the pleura. Am J Clin Pathol 1996;105:189–94.CrossRefGoogle ScholarPubMed
Hainaut, P, Lesage, V, Weynand, B, Coche, E, Noirhomme, P. Calcifying fibrous pseudotumor (CFPT): a patient presenting with multiple pleural lesions. Acta Clin Belg 1999;54:162–164.CrossRefGoogle ScholarPubMed
Kocova, L, Michal, M, Sulc, M, Zamecnik, M. Calcifying fibrous pseudotumour of visceral peritoneum. Histopathology 1997;31:181–184.CrossRefGoogle ScholarPubMed
Soyer, T, Ciftci, AO, Gucer, S, Orhan, D, Senocak, ME. Calcifying fibrous pseudotumor of lung: a previously unreported entity. J Pediatr Surg 2004;39:1729–1730.CrossRefGoogle ScholarPubMed
Dumont, P, Muret, A, Skrobala, D, Robin, P, Toumieux, B. Calcifying fibrous pseudotumor of the mediastinum. Ann Thorac Surg 1997;63:543–544.CrossRefGoogle ScholarPubMed
Chon, SH, Lee, CB, Oh, YH. Calcifying fibrous pseudotumor causing thoracic outlet syndrome. Eur J Cardiothorac Surg 2005;27:353–355.CrossRefGoogle ScholarPubMed
Maeda, A, Kawabata, K, Kusuzaki, K. Rapid recurrence of calcifying fibrous pseudotumor (a case report). Anticancer Res 2002;22:1795–1797.Google Scholar
Ben-Izhak, O, Itin, L, Feuchtwanger, Z, Lifschitz-Mercer, B, Czernobilsky, B. Calcifying fibrous pseudotumor of mesentery presenting with acute peritonitis: case report with immunohistochemical study and review of literature. Int J Surg Pathol 2001;9:249–253.CrossRefGoogle ScholarPubMed
Sigel, JE, Smith, TA, Reith, JD, Goldblum, JR. Immunohistochemical analysis of anaplastic lymphoma kinase expression in deep soft tissue calcifying fibrous pseudotumor: evidence of a late sclerosing stage of inflammatory myofibroblastic tumor?Ann Diagn Pathol 2001;5:10–14.CrossRefGoogle ScholarPubMed
Hill, KA, Gonzalez-Crussi, F, Chou, PM. Calcifying fibrous pseudotumor versus inflammatory myofibroblastic tumor: a histological and immunohistochemical comparison. Mod Pathol 2001;14:784–790.CrossRefGoogle ScholarPubMed
Dorpe, J, Ectors, N, Geboes, K, D'Hoore, A, Sciot, R. Is calcifying fibrous pseudotumor a late sclerosing stage of inflammatory myofibroblastic tumor?Am J Surg Pathol 1999;23:329–335.CrossRefGoogle ScholarPubMed
Reye, RDK. Recurring digital fibrous tumor of childhood. Arch Pathol 1965;80:228–23.Google ScholarPubMed
Allen, PW. Recurring digital fibrous tumor of childhood. Pathology 1972;4:215–223.CrossRefGoogle ScholarPubMed
Beckett, JH, Jacobs, AH. Recurring digital fibrous tumor of childhood: a review. Pediatrics 1977;59:401–406.Google ScholarPubMed
Santa-Cruz, DJ, Reiner, CB. Recurrent digital fibroma of childhood. J Cutan Pathol 1978;5:339–346.CrossRefGoogle ScholarPubMed
Bhawan, J, Bacchetta, C, Joris, I, Majno, G. A myofibroblastic tumor. Infantile digital fibroma (recurrent digital fibrous tumor of childhood). Am J Pathol 1979;94:19–36.Google Scholar
Ishii, N, Matsui, K, Ichiyama, S, Takahashi, Y, Nakajima, H. A case of infantile digital fibromatosis showing spontaneous regression. Br J Dermatol 1989;121:129–133.CrossRefGoogle ScholarPubMed
Rimareix, F, Bardot, J, Anmdrac, L, Vasse, D, Galinier, P, Magalon, G. Infantile digital fibroma – report on eleven cases. Eur J Pediatr Surg 1997;7:345–348.CrossRefGoogle ScholarPubMed
Laskin, WB, Miettinen, M, Fetsch, JF. Infantile digital fibroma/fibromatosis: a clinicopathological and immunohistochemical study of 69 tumors from 57 patients with long-term follow-up. Am J Surg Pathol 2009; 33:1–13.CrossRefGoogle Scholar
Breuning, MH, Oranje, AP, Langemeijer, RA, Hovius, SE, Diepstraten, AF, Hollander, JC. Recurrent digital fibroma, focal dermal hypoplasia, and limb malformations. Am J Med Genet 2000;94:91–101.3.0.CO;2-D>CrossRefGoogle ScholarPubMed
Iwasaki, H, Kikuchi, M, Ohtsuki, I, Enjoji, M, Suenaga, N, Mori, R. Infantile digital fibromatosis. Identification of actin filaments in cytoplasmic inclusions by heavy meromyosin binding. Cancer 1983;52:1653–1661.3.0.CO;2-C>CrossRefGoogle ScholarPubMed
Fringer, B, Thais, H, Bohm, N, Altmannsberger, M, Osborn, M. Identification of actin microfilaments in the intracytoplasmic inclusions present in recurring infantile digital fibromatosis (Reye tumor). Pediatr Pathol 1986;6:311–324.CrossRefGoogle Scholar
Mukai, M, Torikata, C, Iri, H, Hata, J, Naito, M, Shimoda, T. Immunohistochemical identification of aggregated actin filaments in formalin-fixed, paraffin-embedded sections, I. A study of infantile digital fibromatosis by a new pretreatment. Am J Surg Pathol 1992;16:110–115.CrossRefGoogle ScholarPubMed
Hyashi, T, Tsuda, N, Chowdhury, PR, Anami, M, Kishikawa, M, Iseki, M. Infantile digital fibromatosis: a study of the development and regression of cytoplasmic inclusion bodies. Mod Pathol 1995;8:548–552.Google Scholar
Sarma, DP, Hoffmann, EO. Infantile digital fibroma-like tumor in an adult. Arch Dermatol 1980;116:578–579.CrossRefGoogle Scholar
Viale, G, Doglioni, C, Iuzzolino, P, Bontempini, L, Colombi, R, Coggi, G. Infantile digital fibromatosis-like tumour (inclusion body fibromatosis) of adulthood: report of two cases with ultrastructural and immunocytochemical findings. Histopathology 1988;12:415–424.CrossRefGoogle ScholarPubMed
Bittesini, L, DeiTos, AP, Doglioni, C, DellaLibera, D, Laurino, L, Fletcher, CD. Fibro-epithelial tumor of the breast with digital fibroma-like inclusions in the stromal component. Case report with immunocytochemical and ultrastructural analysis. Am J Surg Pathol 1994;18:296–301.CrossRefGoogle Scholar
Hiraoka, N, Mukai, M, Hosoda, Y, Hata, J. Phyllodes tumor of the breast containing the intracytoplasmic inclusion bodies identical with infantile digital fibromatosis. Am J Surg Pathol 1994;18:506–511.CrossRefGoogle ScholarPubMed
Navas-Palacios, JJ, Conde-Zurita, JM. Inclusion body myofibroblasts other than those seen in recurrent digital fibroma of childhood. Ultrastruct Pathol 1984;7:109–121.CrossRefGoogle Scholar
Keasbey, . Juvenile aponeurotic fibroma (calcifying fibroma): A distinctive tumor arising in the palms and soles of young children. Calcifying aponeurotic fibroma. Cancer 1953;6:338–346.3.0.CO;2-M>CrossRefGoogle Scholar
Goldman, RL. The cartilage analogy of fibromatosis (aponeurotic fibroma): further observations based on seven new cases. Cancer 1970;26:1325–1331.3.0.CO;2-M>CrossRefGoogle Scholar
Allen, PW, Enzinger, FM. Juvenile aponeurotic fibroma. Cancer 1970;26:857–867.3.0.CO;2-S>CrossRefGoogle ScholarPubMed
Fetsch, JF, Miettinen, M. Calcifying aponeurotic fibroma: a clinicopathologic study of 22 cases arising in uncommon sites. Hum Pathol 1998;29:1504–1510.CrossRefGoogle ScholarPubMed
Fetsch, JF, Miettinen, M, Laskin, WB, Michal, M, Enzinger, FM. A clinicopathologic study of 45 pediatric soft tissue tumors with an admixture of adipose tissue and fibroblastic elements, and a proposal for classification as lipofibromatosis. Am J Surg Pathol 2000;24:1491–1500.CrossRefGoogle Scholar
Herrmann, BW, Dehner, LP, Forsen, JW. Lipofibromatosis presenting as a pediatric neck mass. Int J Pediatr Otolaryngol 2004;68:1545–1549.CrossRefGoogle ScholarPubMed
Sasaki, D, Hatori, M, Hosaka, M, Watanabe, M, Kokubun, S. Lipofibromatosis arising in a pediatric forearm – a case report. Ups J Med Sci 2005;110:259–266.CrossRefGoogle Scholar
Enzinger, FM. Fibrous tumors of infancy. In: Tumors of Bone and Soft Tissue. Chicago, Year Book Medical Publishers, 1965;231–268.Google Scholar
Wehrli, BM, Weiss, SW, Yandow, S. Garner-associated fibromas (GAF) in young patients: a distinct fibrous lesion that identifies unsuspected Garner syndrome and risk for fibromatosis. Am J Surg Pathol 2001;25:645–651.CrossRefGoogle Scholar
Coffin, CM, Hornick, JL, Zhou, H, Fletcher, CDM. Gardner fibroma: A clinicopathologic and immunohistochemical analysis of 45 patients with 57 fibromas. Am J Surg Pathol 2006;31:410–416.CrossRefGoogle Scholar
Michal, M, Boudova, L, Mukensnabl, P. Gardner's syndrome associated fibromas. Pathol Int 2004;54:523–526.CrossRefGoogle ScholarPubMed
Diwan, AH, Graves, ED, King, JA, Horenstein, MG. Nuchal-type fibroma in two related patients with Gardner's syndrome. Am J Surg Pathol 2000;24:1563–1567.CrossRefGoogle ScholarPubMed
Sternberg, SS. Pathology of juvenile nasopharyngeal angiofibroma; a lesion of adolescent males. Cancer 1954;7:15–28.3.0.CO;2-I>CrossRefGoogle ScholarPubMed
Neel, HB 3rd, Whicker, JH, Devine, KD, Weiland, LH. Juvenile angiofibroma: Review of 120 cases. Am J Surg 1973;126:547–556.CrossRefGoogle ScholarPubMed
Witt, TR, Shah, JP, Sternberg, SS. Juvenile nasopharyngeal angiofibroma: A 30-year clinical review. Am J Surg 1983;146:521–525.CrossRefGoogle ScholarPubMed
Economou, TS, Abemayor, E, Ward, PH. Juvenile nasopharyngeal angiofibroma: an update of the UCLA experience, 1960–1985. Laryngoscope 1988;98:170–175.CrossRefGoogle ScholarPubMed
Ungkanont, K, Byers, RM, Weber, RS, Callender, DL, Wolf, PF, Goepfert, H. Juvenile nasopharyngeal angiofibroma: an update of therapeutic management. Head Neck 1996;18:60–66.3.0.CO;2-X>CrossRefGoogle ScholarPubMed
Enepekides, DJ. Recent advances in the treatment of juvenile angiofibroma. Curr Opin Otolaryngol Head Neck Surg 2004;12:495–499.CrossRefGoogle ScholarPubMed
Onerci, M, Ogretmenoglu, O, Yucel, T. Juvenile nasopharyngeal angiofibroma: a revised staging system. Rhinology 2006;44:39–45.Google ScholarPubMed
Yadav, SP, Singh, I, Chanda, R, Sachdeva, OP. Nasopharyngeal angiofibroma. J Otolaryngol 2002;31:346–350.CrossRefGoogle ScholarPubMed
Giardiello, FM, Hamilton, SR, Krush, AJ, Offerhaus, JA, Booker, SV, Petersen, GM. Nasopharyngeal angiofibroma in patients with familial adenomatous polyposis. Gastroenterology 1993;105:1550–1552.CrossRefGoogle ScholarPubMed
Batsakis, JG, Klopp, CT, Newman, W. Fibrosarcoma arising in a juvenile nasopharyngeal angiofibroma following extensive radiation therapy. Am Surg 1955;21:786–793.Google Scholar
Chen, KT, Bauer, FW. Sarcomatous transformation of nasopharyngeal angiofibroma. Cancer 1982;49:369–371.3.0.CO;2-Y>CrossRefGoogle ScholarPubMed
Spagnolo, DV, Papadimitriou, JM, Archer, M. Postirradiation malignant fibrous histiocytoma arising in juvenile nasopharyngeal angiofibroma and producing alpha-1-antitrypsin. Histopathology 1984;8:339–352.CrossRefGoogle ScholarPubMed
Makek, MS, Andrews, JC, Fisch, U. Malignant transformation of a nasopharyngeal angiofibroma. Laryngoscope 1989;99(10 Pt 1):1088–1092.CrossRefGoogle ScholarPubMed
Beham, A, Fletcher, CD, Kainz, J, Schmid, C, Humer, U. Nasopharyngeal angiofibroma: an immunohistochemical study of 32 cases. Virchows Arch A Pathol Anat Histopathol 1993;423:281–285.CrossRefGoogle ScholarPubMed
Beham, A, Kainz, J, Stammberger, H, Aubock, L, Beham-Schmid, C. Immunohistochemical and electron microscopical characterization of stromal cells in nasopharyngeal angiofibromas. Eur Arch Otorhinolaryngol 1997;254:196–199.CrossRefGoogle ScholarPubMed
Abraham, SC, Montgomery, EA, Giardiello, FM, Wu, TT. Frequent beta-catenin mutations in juvenile nasopharyngeal angiofibromas. Am J Pathol 2001;158:1073–1078.CrossRefGoogle ScholarPubMed
Hwang, HC, Mills, SE, Patterson, K, Gown, AM. Expression of androgen receptors in nasopharyngeal angiofibroma: an immunohistochemical study of 24 cases. Mod Pathol 1998;11:1122–1126.Google ScholarPubMed
Zhang, PJ, Weber, R, Liang, HH, Pasha, TL, LiVolsi, VA. Growth factors and receptors in juvenile nasopharyngeal angiofibroma and nasal polyps: an immunohistochemical study. Arch Pathol Lab Med 2003;127:1480–1484.Google Scholar
Montag, AG, Tretiakova, M, Richardson, M. Steroid hormone receptor expression in nasopharyngeal angiofibromas. Am J Clin Pathol 2006;125:832–837.CrossRefGoogle ScholarPubMed
Enzinger, FM. Fibrous hamartoma of infancy. Cancer 1965;18:241–248.3.0.CO;2-C>CrossRefGoogle ScholarPubMed
Efem, SE, Ekpo, MD. Clinicopathological features of untreated fibrous hamartoma of infancy. J Clin Pathol 1993;46:522–524.CrossRefGoogle ScholarPubMed
Popek, EJ, Montgomery, EA, Fourcroy, JL. Fibrous hamartoma of infancy in the genital region: findings in 15 cases. J Urol 1994;151:990–993.CrossRefGoogle Scholar
Sotelo-Avila, C, Bale, PM. Subdermal fibrous hamartoma of infancy: pathology of 40 cases and differential diagnosis. Pediatr Pathol 1994;14:39–52.CrossRefGoogle ScholarPubMed
Dickey, GE, Sotelo-Avila, C. Fibrous hamartoma of infancy: Current review. Pediatr Dev Pathol 1999;2:236–243.CrossRefGoogle ScholarPubMed
Michal, M, Mukensnabl, P, Chlumska, A, Kodet, R. Fibrous hamartoma of infancy: A study of eight cases with immunohistochemical and electron microscopic findings. Pathol Res Pract 1992;188:1049–1053.CrossRefGoogle Scholar
Carretto, E, Dall'Igna, P, Alaggio, R, Siracusa, F, Granata, C, Ferrari, A. Fibrous hamartoma of infancy: an Italian multi-institutional experience. J Am Acad Dermatol 2006;54:800–803.CrossRefGoogle ScholarPubMed
Lakshminarayanan, R, Konia, T, Welborn, J. Fibrous hamartoma of infancy: a case report with associated cytogenetic findings. Arch Pathol Lab Med 2005;129:520–522.Google ScholarPubMed
Chung, EB, Enzinger, FM. Infantile myofibromatosis: A review of 59 cases with localized and generalized involvement. Cancer 1981;48:1807–1818.3.0.CO;2-G>CrossRefGoogle Scholar
Briselli, MF, Soule, EH, Gilchrist, GS. Congenital fibromatosis. Report of 18 cases of solitary and 4 cases of multiple tumors. Mayo Clin Proc 1980;55:554–562.Google ScholarPubMed
Daimaru, Y, Hashimoto, H, Enjoji, M. Myofibromatosis in adults (adult counterpart of infantile myofibromatosis). Am J Surg Pathol 1989;13:859–865.CrossRefGoogle Scholar
Smith, KJ, Skelton, HG, Barrett, TL, Lupton, GP, Graham, JH. Cutaneous myofibroma. Mod Pathol 1989;2:603–609.Google ScholarPubMed
Foss, RD, Ellis, GL. Myofibromas and myofibromatosis of the oral region: A clinicopathologic analysis of 79 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;89:57–65.CrossRefGoogle ScholarPubMed
Jennings, T, Duray, PH, Collins, FS. Infantile myofibromatosis. Evidence for an autosomal-dominant disorder. Am J Surg Pathol 1984;8:529–538.CrossRefGoogle ScholarPubMed
Wiswell, TE, Davis, J, Cunningham, BE, Solenberger, L, Thomas, PJ. Infantile myofibromatosis: the most common fibrous tumor of infancy. J Pediatr Surg 1988;23:315–318.CrossRefGoogle ScholarPubMed
Coffin, CM, Neilson, KA, Ingels, S, Frank-Gerszberg, R, Dehner, LP. Congenital generalized fibromatosis: a disseminated angiocentric myofibromatosis. Pediatr Pathol Lab Med 1995;15:571–587.CrossRefGoogle Scholar
Fukasawa, Y, Ishikura, H, Takada, A, Yokoyama, S, Imamura, M, Yoshiki, T. Massive apoptosis in infantile myofibromatosis. A putative mechanism for tumor regression. Am J Pathol 1995;144:480–485.Google Scholar
Stenman, G, Nadal, N, Persson, S, Gunterberg, B, Angervall, L. del(6)(q12q15) as the sole cytogenetic abnormality in a case of solitary infantile myofibromatosis. Oncol Rep 1999;6:1101–1104.Google Scholar
Mentzel, T, Calonje, E, Nascimento, AG, Fletcher, CDM. Infantile hemangiopericytoma versus infantile myofibromatosis: Study of a series suggesting a continuous spectrum of infantile myofibroblastic lesions. Am J Surg Pathol 1994;18:922–930.CrossRefGoogle ScholarPubMed
Kitano, Y, Horiki, M, Aoki, T, Sagami, S. Two cases of juvenile hyaline fibromatosis. Some histological, electron microscopic, and tissue culture observations. Arch Dermatol 1972;106:877–883.CrossRefGoogle Scholar
Ishikawa, H, Mori, S. Systemic hyalinosis or fibromatosis hyalinica multiplex juvenilis as a congenital syndrome. A new entity based on the inborn error of acid mucopolysaccharide metabolism in connective tissue cells?Acta Derm Venereol 1973;53:185–191.Google ScholarPubMed
Remberger, K, Krieg, T, Kunze, D, Weinmann, HM, Hubner, G. Fibromatosis hyalinica multiplex (juvenile hyalin fibromatosis). Light microscopic, electron microscopic, immunohistochemical, and biochemical findings. Cancer 1985;56:614–624.3.0.CO;2-T>CrossRefGoogle ScholarPubMed
Fayad, MN, Yacoub, A, Salman, S, Khudr, A, Kaloustian, VM. Juvenile hyaline fibromatosis: two new patients and review of the literature. Am J Med Genet 1987;26:123–131.CrossRefGoogle ScholarPubMed
Mancini, GM, Stojanov, L, Willemsen, R, Kleijer, WJ, Huijmans, JG, Diggelen, OP. Juvenile hyaline fibromatosis: clinical heterogeneity in three patients. Dermatology 1999;198:18–25.CrossRefGoogle ScholarPubMed
Senzaki, H, Kiyozuka, Y, Uemura, Y, Shikata, N, Ueda, S, Tsubura, A. Juvenile hyaline fibromatosis: a report of two unrelated adult sibling cases and a literature review. Pathol Int 1998;48:230–236.CrossRefGoogle Scholar
Haleem, A, Al-Hindi, HN, Joboury, MA, Husseini, HA, Ajlan, AA. Juvenile hyaline fibromatosis: morphologic, immunohistochemical, and ultrastructural study of three siblings. Am J Dermatopathol 2002;24:218–224.CrossRefGoogle ScholarPubMed
Landing, BH, Nadorra, R. Infantile systemic hyalinosis: report of four cases of a disease, fatal in infancy, apparently different from juvenile systemic hyalinosis. Pediatr Pathol 1986;6:55–79.CrossRefGoogle ScholarPubMed
Dowling, O, Difeo, A, Ramirez, MC, Tukel, T, Narla, G, Bonafe, L. Mutations in capillary morphogenesis gene-2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis. Am J Hum Genet 2003;73:957–966.CrossRefGoogle ScholarPubMed
Hanks, S, Adams, S, Douglas, J, Arbour, L, Atherton, DJ, Balci, S. Mutations in the gene encoding capillary morphogenesis protein 2 cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Am J Hum Genet 2003;73:791–800.CrossRefGoogle ScholarPubMed
Wiedemann, HR, Burgio, GR, Aldenhoff, P, Kunze, J, Kaufmann, HJ, Schilg, E. The proteus syndrome. Partial gigantism of the hands and/or feet, nevi, hemihypertrophy, subcutaneous tumors, macroceophaly, or other skull anomalies, and possible accelerated growth and visceral affections. Eur J Pediatr 1983;140:5–12.CrossRefGoogle ScholarPubMed
Biesecker, LG, Happle, R, Mulliken, JB, Weksberg, R, Graham, JM Jr, Viljoen, DL. Proteus syndrome: Diagnostic criteria, differential diagnosis, and patient evaluation. Am J Med Genet 1999;84:389–395.3.0.CO;2-O>CrossRefGoogle ScholarPubMed
Nguyen, T, Turner, JT, Olsen, C, Biesecker, LG, Darling, TN. Cutaneous manifestations of Proteus syndrome: correlations with general clinical severity. Arch Dermatol 2004;140:1001–1002.CrossRefGoogle ScholarPubMed
Twede, JV, Turner, JT, Biesecker, LG, Darling, TN. Evolution of skin lesions in Proteus syndrome. J Am Acad Dermatol 2005;52:834–838.CrossRefGoogle ScholarPubMed
Gordon, PL, Wilroy, LS, Lasater, OE, Cohen, MM. Neoplasms in Proteus syndrome. Am J Med Genet 1995;57:74–78.CrossRefGoogle ScholarPubMed
Loffeld, A, McLellan, NJ, Cole, T, Payne, SJ, Fricker, D, Moss, C. Epidermal naevus in Proteus syndrome showing loss of heterozygosity for an inherited PTEN mutation. Br J Dermatol 2006;154:1194–1198.CrossRefGoogle ScholarPubMed

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