Book contents
- Frontmatter
- Contents
- List of contributors
- Preface
- 1 A short history of latent inhibition research
- Current topics in latent inhibition research
- 2 Latent inhibition and extinction: their signature phenomena and the role of prediction error
- 3 Inter-stage context and time as determinants of latent inhibition
- 4 Latent inhibition: acquisition or performance deficit?
- 5 Latent inhibition and learned irrelevance in human contingency learning
- 6 Associative and nonassociative processes in latent inhibition: an elaboration of the Pearce–Hall model
- 7 From latent inhibition to retrospective revaluation: an attentional-associative model
- 8 Latent inhibition and habituation: evaluation of an associative analysis
- 9 Latent inhibition and creativity
- 10 The phylogenetic distribution of latent inhibition
- 11 The genetics of latent inhibition: studies of inbred and mutant mice
- 12 A comparison of mechanisms underlying the CS–US association and the CS–nothing association
- 13 The pharmacology of latent inhibition and its relevance to schizophrenia
- 14 Parahippocampal region–dopaminergic neuron relationships in latent inhibition
- 15 Latent inhibition and other salience modulation effects: same neural substrates?
- 16 What the brain teaches us about latent inhibition (LI): the neural substrates of the expression and prevention of LI
- 17 Latent inhibition in schizophrenia and schizotypy: a review of the empirical literature
- 18 A cautionary note about latent inhibition in schizophrenia: are we ignoring relevant information?
- 19 Latent inhibition as a function of anxiety and stress: implications for schizophrenia
- 20 Nicotinic modulation of attentional deficits in schizophrenia
- 21 Latent inhibition and schizophrenia: the ins and outs of context
- Summary and conclusions
- Index
- References
4 - Latent inhibition: acquisition or performance deficit?
from Current topics in latent inhibition research
Published online by Cambridge University Press: 04 August 2010
Book contents
- Frontmatter
- Contents
- List of contributors
- Preface
- 1 A short history of latent inhibition research
- Current topics in latent inhibition research
- 2 Latent inhibition and extinction: their signature phenomena and the role of prediction error
- 3 Inter-stage context and time as determinants of latent inhibition
- 4 Latent inhibition: acquisition or performance deficit?
- 5 Latent inhibition and learned irrelevance in human contingency learning
- 6 Associative and nonassociative processes in latent inhibition: an elaboration of the Pearce–Hall model
- 7 From latent inhibition to retrospective revaluation: an attentional-associative model
- 8 Latent inhibition and habituation: evaluation of an associative analysis
- 9 Latent inhibition and creativity
- 10 The phylogenetic distribution of latent inhibition
- 11 The genetics of latent inhibition: studies of inbred and mutant mice
- 12 A comparison of mechanisms underlying the CS–US association and the CS–nothing association
- 13 The pharmacology of latent inhibition and its relevance to schizophrenia
- 14 Parahippocampal region–dopaminergic neuron relationships in latent inhibition
- 15 Latent inhibition and other salience modulation effects: same neural substrates?
- 16 What the brain teaches us about latent inhibition (LI): the neural substrates of the expression and prevention of LI
- 17 Latent inhibition in schizophrenia and schizotypy: a review of the empirical literature
- 18 A cautionary note about latent inhibition in schizophrenia: are we ignoring relevant information?
- 19 Latent inhibition as a function of anxiety and stress: implications for schizophrenia
- 20 Nicotinic modulation of attentional deficits in schizophrenia
- 21 Latent inhibition and schizophrenia: the ins and outs of context
- Summary and conclusions
- Index
- References
Summary
What one knows and what one shows: acquisition vs. performance
Since the time of Aristotle, it has been commonly assumed that two events occurring in close proximity become associated to each other. This learning by contiguity is a central determinant of the phenomenon of classical conditioning, in which a neutral target stimulus (X) is repeatedly presented in close proximity to a stimulus that unconditionally produces a response (i.e., an unconditioned stimulus, US), with the consequence that X comes to elicit a response appropriate to the US. That is, X becomes a conditioned stimulus (CS) that produces a conditioned response (CR). However, there have been reports of various conditions under which CS–US pairings fail to result in an acquired response to the CS. For example, even though pairings of X and the US ordinarily result in a robust CR (i.e., acquisition), X will fail to gain response potential if it is trained in the presence of another, more salient CS, A (i.e., overshadowing; Pavlov,1927). Thus, even though the contiguity between CS X and the US is the same in the X–US acquisition and AX–US overshadowing conditions, the resulting behavioral control by CS X is not. An easy explanation for this difference is that subjects did not acquire an X–US association in the overshadowing condition.
- Type
- Chapter
- Information
- Latent InhibitionCognition, Neuroscience and Applications to Schizophrenia, pp. 62 - 93Publisher: Cambridge University PressPrint publication year: 2010
References
, , & (1994). Interval between preexposure and test determines the magnitude of latent inhibition: implications for an interference account. Animal Learning & Behavior, 22, 188–194.CrossRefGoogle Scholar
, & (2005). Simulations of a modified SOP model applied to retrospective revaluation of human causal judgments. Learning & Behavior, 33, 147–159.CrossRefGoogle Scholar
, , & (1987). Extending conditioned stimuli before versus after unconditioned stimuli: implications for real-time models of conditioning. Journal of Experimental Psychology: Animal Behavior Processes, 13, 168–181.Google Scholar
, & (1982). Extinction of the context and latent inhibition. Learning and Motivation, 13, 391–416.CrossRefGoogle Scholar
, , , & (2001). Contingency learning and causal reasoning. In & (Eds.), Handbook of Contemporary Learning Theories. Mahwah, NJ: Erlbaum, pp. 255–306.Google Scholar
, , & (1988). Differential performance of acute and chronic schizophrenics in a latent inhibition task. The Journal of Nervous and Mental Disease, 176, 598–606.CrossRefGoogle Scholar
, , , & (2001). Conditioned blocking and schizophrenia: a replication and study of the role of symptoms, age, onset-age of psychosis and illness duration. Schizophrenia Research, 49, 157–170.CrossRefGoogle ScholarPubMed
, , , & (1998). Overshadowing and latent inhibition counteract each other: support for the comparator hypothesis. Journal of Experimental Psychology: Animal Behavior Processes, 24, 335–351.Google ScholarPubMed
(1991). Context and retrieval in extinction and in other examples of interference in simple associative learning. In and (Eds.), Current Topics in Animal Learning: Brain, Emotion, and Cognition. Hillsdale, NJ: Erlbaum, pp. 25–53.Google Scholar
(1993). Context, time, and memory retrieval in the interference paradigms of Pavlovian learning. Psychological Bulletin, 114, 80–99.CrossRefGoogle ScholarPubMed
(1994). Context, ambiguity, and classical conditioning. Current Directions in Psychological Science, 3, 49–53.CrossRefGoogle Scholar
(1997). Signals for whether versus when an event will occur. In & (Eds.), Learning, Motivation, and Cognition: The Functional Behaviorism of Robert C. Bolles. Washington DC: American Psychological Association, pp. 385–409.CrossRefGoogle Scholar
, & (1989). Slow reacquisition following extinction: context, encoding, and retrieval mechanisms. Journal of Experimental Psychology: Animal Behavior Processes, 15, 43–53.Google Scholar
, , & (2003). Stimulus representation in SOP: I. Theoretical rationalization and some interpretations. Behavioural Processes, 62, 5–25.CrossRefGoogle Scholar
, & (1983). Contextual effects in latent inhibition with an appetitive conditioning procedure. Animal Learning & Behavior, 11, 67–74.CrossRefGoogle Scholar
, & (1992). Context, cortex, and dopamine: a connectionist approach to behavior and biology in schizophrenia. Psychological Review, 99, 45–77.CrossRefGoogle Scholar
, & (2000). Superlatent inhibition with delayed conditioned taste aversion testing. Animal Learning & Behavior, 28, 389–399.CrossRefGoogle Scholar
, , & (2001). The extended comparator hypothesis: learning by contiguity, responding by relative strength. In & (Eds.), Handbook of Contemporary Learning Theories. Hillsdale, NJ: Erlbaum, pp. 65–117.Google Scholar
, , , et al. (1987). Latent inhibition: a trace conditioning phenomenon?Learning and Motivation, 18, 185–201.CrossRefGoogle Scholar
, & (1996). Within-compound associations mediate the retrospective revaluation of causality judgments. Quarterly Journal of Experimental Psychology, 49B, 60–80.CrossRefGoogle Scholar
, , & (2002). Latent inhibition and contextual associations. Journal of Experimental Psychology: Animal Behavior Processes, 28, 123–136.Google ScholarPubMed
, , , & (2004). Interference and time: a brief review and an integration. Reviews in the Neurosciences, 15, 415–438.CrossRefGoogle ScholarPubMed
, , & (2002). Associative deficit accounts of disrupted latent inhibition and blocking in schizophrenia. Neuroscience and Biobehavioral Reviews, 26, 203–216.CrossRefGoogle Scholar
, & (1991). An animal model of attention deficit. In , , and (Eds.), Neuromethods, vol. 18: Animal Models in Psychiatry I. Clifton, NJ: Humana Press, pp. 313–361.CrossRefGoogle Scholar
, , , & (1998). Comparator mechanisms and conditioned inhibition: CS preexposure disrupts Pavlovian conditioned inhibition but not explicitly unpaired inhibition. Journal of Experimental Psychology: Animal Behavior Processes, 24, 453–466.Google Scholar
, , , & (1994). Latent inhibition as a performance deficit resulting from CS-context associations. Animal Learning & Behavior, 22, 395–408.CrossRefGoogle Scholar
, , , & (1995). Latent inhibition in drug naïve schizophrenics: relationship to duration of illness and dopamine D2 binding using SPECT. Schizophrenia Research, 17, 95–107.CrossRefGoogle Scholar
, & (1984). A search for context-stimulus associations in latent inhibition. Quarterly Journal of Experimental Psychology, 36, 145–169.CrossRefGoogle Scholar
(1992). Occasion setting in Pavlovian conditioning. In (Ed.), The Psychology of Learning and Motivation, vol. 28. San Diego: Academic Press, pp. 69–125.Google Scholar
, & (1988). Overshadowing and blocking procedures in latent inhibition. Quarterly Journal of Experimental Psychology, 40B, 163–186.Google Scholar
(1999). Attenuation of latent inhibition after compound conditioning. Japanese Psychological Research, 41, 102–111.CrossRefGoogle Scholar
, , & (1992). Loss of the Kamin blocking effect in acute but not chronic schizophrenics. Biological Psychiatry, 32, 739–755.CrossRefGoogle Scholar
, , , & (1997). Disruption of the Kamin blocking effect in schizophrenia and in normal subjects following amphetamine. Behavioural Brain Research, 88, 103–114.CrossRefGoogle ScholarPubMed
(1968). “Attention-like” processes in classical conditioning. In (Ed.), Miami Symposium on the Prediction Of Behavior: Aversive Stimulation. Miami, FL: University of Miami Press, pp. 9–31.Google Scholar
, , , & (1984). Attenuation of latent inhibition by post-acquisition reminder. Quarterly Journal of Experimental Psychology, 36B, 53–63.CrossRefGoogle Scholar
, & (1981). A nonassociative aspect of overshadowing. Bulletin of the Psychonomic Society, 18, 318–320.CrossRefGoogle Scholar
, , , & (1998). Loss of latent inhibition of contextual conditioning following non-reinforced context exposure in rats. Quarterly Journal of Experimental Psychology, 51B, 75–90.Google Scholar
, , & (1991). Release from latent inhibition with delayed testing. Animal Learning & Behavior, 19, 139–145.CrossRefGoogle Scholar
, & (1984). The influence of flavor preexposure and test interval on conditioned taste aversions in the rat. Learning and Motivation, 15, 259–278.CrossRefGoogle Scholar
, , , & (2002). Effects of typical and atypical antipsychotics on prepulse inhibition and latent inhibition in chronic schizophrenia. Biological Psychiatry, 52, 729–739.CrossRefGoogle ScholarPubMed
, & (2002). Taste aversion after ingestion of lithium chloride: an associative analysis. Quarterly Journal of Experimental Psychology, 55B, 365–380.CrossRefGoogle Scholar
(1989). Latent Inhibition and Conditioned Attention Theory. Cambridge: Cambridge University Press.CrossRefGoogle Scholar
(1997). Latent inhibition as a measure of learned inattention: some problems and solutions. Behavioural Brain Research, 88, 75–83.CrossRefGoogle ScholarPubMed
(2005). Construct validity of the animal latent inhibition model of selective attention deficits in schizophrenia. Schizophrenia Bulletin, 31, 139–153.CrossRefGoogle Scholar
, & (1995). Latent inhibition in humans: data, theory, and implications for schizophrenia. Psychological Bulletin, 117, 87–103.CrossRefGoogle Scholar
, & (1959). Latent inhibition: the effect of nonreinforced preexposure to the conditioned stimulus. Journal of Comparative and Physiological Psychology, 52, 415–419.CrossRefGoogle Scholar
, , & (1976). Latent inhibition and conditioned attention theory. Journal of Experimental Psychology: Animal Behavior Processes, 2, 163–174.Google Scholar
, , & (1982). The effects of compound stimulus preexposure of two elements differing in salience on the acquisition of conditioned suppression. Animal Learning & Behavior, 10, 483–489.CrossRefGoogle Scholar
, , , & (1987). Latent inhibition and schizophrenia. Bulletin of the Psychonomic Society, 25, 464–467.CrossRefGoogle Scholar
, , & (1981). Conditioned attention theory. In (Ed.), The Psychology of Learning and Motivation, vol. 15. New York: Academic Press, pp. 1–49.Google Scholar
(1975). A theory of attention: variations in the associability of stimuli with reinforcement. Psychological Review, 82, 276–298.CrossRefGoogle Scholar
, , & (1985). Recovery of an overshadowed association achieved by extinction of the overshadowed stimulus. Learning and Motivation, 16, 398–412.CrossRefGoogle Scholar
, , , & (2009). Protection from latent inhibition provided by a conditioned inhibitor. Journal of Experimental Psychology: Animal Behavior Processes, 35, 498–508.Google ScholarPubMed
, , , , & (1994). Latent inhibition, context specificity, and context familiarity. Quarterly Journal of Experimental Psychology, 47B, 387–400.Google Scholar
, , & (1989). An associative theory of the representation of stimuli: applications to perceptual learning and latent inhibition. In (Ed.), Parallel Distributed Processing: Implications for Psychology and Neurobiology. Oxford, UK: Oxford University Press, pp. 102–130.Google Scholar
, & (2000). An elemental model of associative learning. I. Latent inhibition and perceptual learning. Animal Learning & Behavior, 28, 211–246.CrossRefGoogle Scholar
, , & (1995). Assessment of the Rescorla-Wagner model. Psychological Bulletin, 117, 363–386.CrossRefGoogle ScholarPubMed
, & (2002). Associative interference between cues and between outcomes presented together and presented apart: an integration. Behavioural Processes, 57, 163–185.CrossRefGoogle Scholar
, , & (1992). Overshadowing-like effects between potential comparator stimuli: covariation in comparator roles of context and punctuate excitor used in inhibitory training as a function of excitor salience. Learning and Motivation, 23, 1–26.CrossRefGoogle Scholar
, & (1988). The comparator hypothesis: a response rule for the expression of associations. In (Ed.), The Psychology of Learning and Motivation, vol. 22. San Diego, CA: Academic Press, pp. 51–92.Google Scholar
, & (1998). Analogies between occasion setting and Pavlovian conditioning. In and (Eds.), Occasion Setting: Associative Learning and Cognition in Animals. Washington DC: American Psychological Association, pp. 3–35.CrossRefGoogle Scholar
, , , & (2003). Reduced Kamin blocking in non paranoid schizophrenia: associations with schizotypy. Journal of Psychiatric Research, 37, 155–163.CrossRefGoogle ScholarPubMed
, , & (1999). Summation of overshadowing and latent inhibition in rats' conditioned taste aversion: scapegoat technique works for familiar meals. Appetite, 33, 299–307.CrossRefGoogle ScholarPubMed
, & (2005). Summation of latent inhibition and overshadowing in a generalized bait shyness paradigm of rats. Behavioural Processes, 69, 369–377.CrossRefGoogle Scholar
(2002). Context specificity of excitation and inhibition in ambiguous stimuli. Learning and Motivation, 33, 284–310.CrossRefGoogle Scholar
(1997). Stimulus dimension shifts in patients with schizophrenia, with and without paranoid hallucinatory symptoms, or obsessive compulsive disorder: strategies, blocking, and monoamine status. Behavioural Brain Research, 88, 115–131.CrossRefGoogle ScholarPubMed
, , & (1996). Conditioned blocking in patients with paranoid, non-paranoid psychosis or obsessive compulsive disorder: associations with symptoms, personality and monoamine metabolism. Journal of Psychiatric Research, 30, 369–390.CrossRefGoogle ScholarPubMed
, , & (1999). Latent inhibition in animals as a model of acute schizophrenia: a re-analysis. In and (Eds.), Animal Models of Human Emotion and Cognition. Washington DC: American Psychological Association.Google Scholar
, & (1980). A model for Pavlovian learning: variations in the effectiveness of conditioned but not of unconditioned stimuli. Psychological Review, 87, 532–552.CrossRefGoogle Scholar
(1995). Compound stimulus preexposure effects in an appetitive conditioning procedure. Learning and Motivation, 26, 1–10.CrossRefGoogle Scholar
, & (1972). CS habituation produces a “latent inhibition effect” but no active “conditioned inhibition”. Learning and Motivation, 3, 237–245.CrossRefGoogle Scholar
(1971). Variation in the effectiveness of reinforcement and nonreinforcement following prior inhibitory conditioning. Learning and Motivation, 2, 113–123.CrossRefGoogle Scholar
, & (1972). A theory of Pavlovian conditioning: variations in the effectiveness of reinforcement and non-reinforcement. In and (Eds.), Classical Conditioning II: Current Theory and Research. New York: Appleton-Century Crofts, pp. 64–99.Google Scholar
, & (1997). Additivity of the effects of retention interval and context change on latent inhibition: toward resolution of the context forgetting paradox. Journal of Experimental Psychology: Animal Behavior Processes, 23, 283–294.Google ScholarPubMed
(1947). The Integrative Action of the Central Nervous System. Cambridge: Cambridge University Press.Google Scholar
, & (2009). Spontaneous recovery of excitation and inhibition. Journal of Experimental Psychology: Animal Behavior Processes, 35, 419–426.Google Scholar
, & (2007). Sometimes-competing retrieval (SOCR): a formalization of the comparator hypothesis. Psychological Review, 114, 759–783.CrossRefGoogle ScholarPubMed
, , , , & (1996). Latent inhibition in schizophrenia. Schizophrenia Research, 20, 91–103.CrossRefGoogle Scholar
, , , et al. (2005). Intact visual latent inhibition in schizophrenia patients in a within-subject paradigm. Schizophrenia Research, 72, 169–183.CrossRefGoogle Scholar
, & (1930). Introduction and removal of reward, and maze performance in rats. University of California Publications in Psychology, 4, 257–275.Google Scholar
, , , & (2005). An extended comparator hypothesis account of superconditioning. Journal of Experimental Psychology: Animal Behavior Processes, 31, 184–198.Google ScholarPubMed
, , , et al. (2002). Latent inhibition and schizophrenia: Pavlovian conditioning of autonomic responses. Schizophrenia Research, 55, 147–158.CrossRefGoogle ScholarPubMed
(1979). Habituation and memory. In & (Eds.), Mechanisms of Learning and Motivation: A Memorial to Jerzy Konorski. Hillsdale, NJ: Erlbaum, pp. 53–82.Google Scholar
(1981). SOP: a model of automatic memory processing in animal behavior. In and (Eds.), Information Processing in Animals: Memory Mechanisms. Hillsdale, NJ: Erlbaum, pp. 5–47.Google Scholar
, & (1989). Evolution of a structure connectionist model of Pavlovian conditioning (ÆSOP). In & (Eds.), Contemporary Learning Theories: Pavlovian Conditioning and the Status of Traditional Learning Theory. Hillsdale, NJ: Erlbaum, pp. 149–189.Google Scholar
, & (2001). A componential theory of Pavlovian conditioning. In & (Eds.), Handbook of Contemporary Learning Theories. Mahwah, NJ: Erlbaum, pp. 23–64.Google Scholar
, , & (1981). Short- and long-term decrements in toxicosis-induced odor-aversion learning: the role of duration of exposure to an odor. Journal of Experimental Psychology: Animal Behavior Processes, 7, 362–381.Google Scholar
, , & (2003). Massive preexposure and preexposure in multiple contexts attenuate the context specificity of latent inhibition. Learning & Behavior, 31, 378–386.CrossRefGoogle ScholarPubMed
, & (2007). Interactions between retroactive interference and context-mediated treatments that impair Pavlovian conditioned responding. Learning & Behavior, 35, 27–35.CrossRefGoogle ScholarPubMed
, & (2008). Determinants of cue interaction. Behavioural Processes, 78, 191–203.CrossRefGoogle Scholar
, , & (2004). Interaction of retention interval with CS-preexposure and extinction treatments: symmetry with respect to primacy. Learning & Behavior, 32, 335–347.CrossRefGoogle Scholar
, , , , , & (1998). Reduced latent inhibition in people with schizophrenia: an effect of psychosis or of its treatment. British Journal of Psychiatry, 172, 243–249.CrossRefGoogle ScholarPubMed
, , , & (2004). Latent inhibition and overswitching in schizophrenia. Schizophrenia Bulletin, 30, 713–726.CrossRefGoogle Scholar
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