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Chapter 38 - Fertility Preservation

Ethical Considerations

from Section 10 - Ethical, Legal, and Religious Issues

Published online by Cambridge University Press:  27 March 2021

By
Pasquale Patrizio  and
Arthur L Caplan
Edited by
Jacques Donnez  and
S. Samuel Kim
Jacques Donnez
Affiliation:
Catholic University of Louvain, Brussels
S. Samuel Kim
Affiliation:
University of Kansas School of Medicine
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Summary

One of the consequences of cancer therapies, including radiation and chemotherapy, is gonadotoxicity. As effective treatments have rendered a number of malignancies curable, or have delivered long-term survival, post-treatment fertility has emerged as an important consideration for patients and their healthcare providers. Unfortunately, there are currently no definitive ways to limit the injurious effects of these treatments on gonadal function, other than shielding the gonads from direct exposure to ionizing radiation. Suppression of gonadotropin secretion may have a protective effect in some populations and with certain treatment regimens (e.g., alkylating agents), but the general efficacy of this intervention for preserving fertility remains uncertain.

Type
Chapter
Information
Fertility Preservation
Principles and Practice
 , pp. 433 - 441
Publisher: Cambridge University Press
Print publication year: 2021

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