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Chapter 37 - Predicting Ovarian Futures

The Contribution of Genetics

from Section 9 - New Research and Technologies

Published online by Cambridge University Press:  27 March 2021

By
Elizabeth McGee  and
Jerome F Strauss
Edited by
Jacques Donnez  and
S. Samuel Kim
Jacques Donnez
Affiliation:
Catholic University of Louvain, Brussels
S. Samuel Kim
Affiliation:
University of Kansas School of Medicine
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Summary

The first live birth to occur after ovarian-tissue transplantation between two genetically different sisters was reported in 2011. Since this is an acceptable practice with monozygotic twins, there is no apparent reason to refrain from using it with genetically different sisters, especially if one of the sisters previously received bone marrow from the other, leading to complete chimerism (HLA compatibility) between donor and recipient, thus obviating the need for immunosuppressive treatment. This approach allows for natural conception, which could be important on moral, ethical or religious grounds.

Type
Chapter
Information
Fertility Preservation
Principles and Practice
 , pp. 420 - 432
Publisher: Cambridge University Press
Print publication year: 2021

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