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Chapter 14 - Hypoxia and Shunts

from Section 2 - Respiratory Physiology

Published online by Cambridge University Press:  31 July 2019

David Chambers ,
Christopher Huang  and
Gareth Matthews
David Chambers
Affiliation:
Salford Royal NHS Foundation Trust
Christopher Huang
Affiliation:
University of Cambridge
Gareth Matthews
Affiliation:
University of Cambridge
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Summary

Hypoxia refers specifically to the situation in which tissues are unable to undergo aerobic metabolism. Hypoxaemia refers specifically to reduced PaO2. This can result from either a failure of O2 delivery or a failure of O2 utilisation. The following conditions must be fulfilled for cells to utilise O2 for aerobic metabolism.

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Chapter
Information
Basic Physiology for Anaesthetists , pp. 63 - 67
Publisher: Cambridge University Press
Print publication year: 2019

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References

Further reading

Lumb, A. B.. Distribution of pulmonary ventilation and perfusion. In: Lumb, A. B.. Nunn’s Applied Respiratory Physiology, 8th edition. London, Churchill Livingstone, 2016; 109–36.Google Scholar
Gossage, J. R., Kanj, G.. Pulmonary arteriovenous malformations. A state of the art review. Am J Respir Crit Care Med 1998; 158(2): 643–61.CrossRefGoogle ScholarPubMed

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