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Section 3 - Cardiovascular Physiology

Published online by Cambridge University Press:  31 July 2019

David Chambers ,
Christopher Huang  and
Gareth Matthews
David Chambers
Affiliation:
Salford Royal NHS Foundation Trust
Christopher Huang
Affiliation:
University of Cambridge
Gareth Matthews
Affiliation:
University of Cambridge
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Basic Physiology for Anaesthetists , pp. 111 - 188
Publisher: Cambridge University Press
Print publication year: 2019

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References

Further reading

Herring, N., Paterson, D. J.. Overview of the cardiovascular system. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 1–14.Google Scholar
Herring, N., Paterson, D. J.. Specialisation in individual circulations. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 275–302.Google Scholar
Anderson, R. H., Spicer, D. E., Hlavacek, A. M., et al. Wilcox’s Surgical Anatomy of the Heart, 4th edition. Cambridge, Cambridge University Press, 2013.CrossRefGoogle Scholar
Barash, P., Akhtar, S.. Coronary stents: factors contributing to perioperative major adverse cardiovascular events. Br J Anaesth 2010; 105(Suppl. 1): u3–15.CrossRefGoogle ScholarPubMed
Biccard, B. M., Rodseth, R. N.. The pathophysiology of perioperative myocardial infarction. Anaesthesia 2010; 65(7): 733–41.CrossRefGoogle Scholar
Ramanathan, T., Skinner, H.. Coronary blood flow. Continuing Educ Anaesth Crit Care Pain 2005; 5(2): 61–4.CrossRefGoogle Scholar
Herring, N., Paterson, D. J.. ECG diagnosis of acute ischaemia and infarction: past, present and future. Q J Med 2006; 99(4): 219–30.CrossRefGoogle ScholarPubMed

Further reading

Herring, N., Paterson, D. J.. The cardiac cycle. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 15–28.Google Scholar
Holmes, K., Vohra, H. A.. Mitral valve and mitral valve disease. BJA Education 2017; 17(1): 1–9.CrossRefGoogle Scholar
Brown, J., Morgan-Hughes, N. J.. Aortic stenosis and non-cardiac surgery. Continuing Educ Anaesth Crit Care Pain 2005; 5(1): 1–4.CrossRefGoogle Scholar
Cheitlin, M. D.. Cardiovascular physiology – changes with aging. Am J Geriatr Cardiol 2003; 12(1): 9–13.CrossRefGoogle ScholarPubMed

Further reading

Herring, N., Paterson, D. J.. Control of stroke volume and cardiac output. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 87–112.Google Scholar
Herring, N., Paterson, D. J.. Assessment of cardiac output and arterial pulse. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 113–20.Google Scholar
Reuter, D. A., Kalman, S.. From ‘goal-directed haemodynamic therapy’ to ‘individualised perioperative haemodynamic management’. Br J Anaesth 2018; 120(4): 615–6.CrossRefGoogle ScholarPubMed
Michard, F., Giglio, M. T., Brienza, N.. Perioperative goal-directed therapy with uncalibrated pulse contour methods: impact on fluid management and postoperative outcome. Br J Anaesth 2017; 119(1): 22–30.CrossRefGoogle ScholarPubMed
Saugel, B., Cecconi, M., Wagner, J. Y., et al. Noninvasive continuous cardiac output monitoring in perioperative and intensive care medicine. Br J Anaesth 2015; 114(4): 562–75.CrossRefGoogle ScholarPubMed
Ghosh, S., Arthur, B., Klein, A. A.. NICE guidance on CardioQ™ oesophageal Doppler monitoring. Anaesthesia 2011; 66(12): 1081–7.CrossRefGoogle ScholarPubMed
Jhanji, S., Dawson, J., Pearse, R. M.. Cardiac output monitoring: basic science and clinical application. Anaesthesia 2008; 63: 172–81.CrossRefGoogle ScholarPubMed

Further reading

Herring, N., Paterson, D. J.. Control of stroke volume and cardiac output. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 87–112.Google Scholar
Fukuta, H., Little, W. C.. The cardiac cycle and the physiological basis of left ventricular contraction, ejection, relaxation and filling. Heart Fail Clin 2008; 4(1): 1–11.CrossRefGoogle ScholarPubMed
Pirracchio, R., Cholley, B., De Hert, S., et al. Diastolic heart failure in anaesthesia and critical care. Br J Anaesth 2007; 98(6): 707–21.CrossRefGoogle ScholarPubMed
Groban, L., Butterworth, J.. Perioperative management of chronic heart failure. Anesth Analg 2006; 103(3): 557–75.CrossRefGoogle ScholarPubMed
Mandinov, L., Eberli, F. R., Seiler, C., et al. Diastolic heart failure. Cardiovasc Res 2000; 45(4): 813–25.CrossRefGoogle ScholarPubMed

Further reading

Klabunde, R. E.. Cardiovascular Physiology Concepts, 2nd edition. Philadelphia, Lippincott Williams & Wilkins, 2011.Google Scholar

Further reading

Kaski, J. C., Hausenloy, D. J., Gersh, B. J., Yellon, D. M. (Eds.). Management of Myocardial Reperfusion Injury. Berlin, Springer, 2012.CrossRefGoogle Scholar
Pinski, M. R., Artigas, A., Dhainaut, J. F.. Coronary Circulation and Myocardial Ischemia. New York, Springer-Verlag, 2002.Google Scholar
van Lier, F., Wesdorp, F. H. I. M., Liem, V. G. B., et al. Association between postoperative mean arterial blood pressure and myocardial injury after non-cardiac surgery. Br J Anaesth 2018; 120(1): 77–83.CrossRefGoogle Scholar
Chapman, A. R., Adamson, P. D., Mills, N. L.. Assessment and classification of patients with myocardial injury and infarction in clinical practice. Heart 2017; 103: 10–18.CrossRefGoogle ScholarPubMed
Ekeloef, S., Alamili, M., Devereaux, P. J., et al. Troponin elevations after non-cardiac, non-vascular surgery are predictive of major adverse cardiac events and mortality: a systematic review and meta-analysis. Br J Anaesth 2016; 117(5): 559–68.CrossRefGoogle ScholarPubMed
Zhang, Z.-M., Rautaharju, P. M., Prineas, R. J., et al. Race and sex differences in the incidence and prognostic significance of silent myocardial infarction in the Atherosclerosis Risk In Communities (ARIC) study. Circulation 2016; 133(22): 2141–8.CrossRefGoogle ScholarPubMed
Foreman, R. D., Garrett, K. M., Blair, R. W.. Mechanisms of cardiac pain. Compr Physiol 2015; 5: 929–60.Google Scholar
Loveridge, R., Schroeder, F.. Anaesthetic preconditioning. Continuing Educ Anaesth Crit Care Pain 2010; 10(2): 38–42.CrossRefGoogle Scholar

Further reading

Herring, N., Paterson, D. J.. Haemodynamics: flow, pressure and resistance. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 113–20.Google Scholar
Heller, L., Mohrman, D.. The peripheral vascular system. In: Heller, L., Mohrman, D.. Cardiovascular Physiology, 9th edition. New York, Lange McGraw-Hill, 2018; 104–27.Google Scholar

Further reading

Herring, N., Paterson, D. J.. Haemodynamics: flow, pressure and resistance. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 113–20.Google Scholar
Vlachopoulos, C., O’Rourke, M., Nichols, W. W.. McDonald’s Blood Flow in Arteries: Theoretical, Experimental and Clinical Principles, 6th edition. Boca Raton, CRC Press, 2011.CrossRefGoogle Scholar
Lakhal, K., Ehrmann, S., Martin, M., et al. Blood pressure monitoring during arrhythmia: agreement between automated brachial cuff and intra-arterial measurements. Br J Anaesth 2015; 115(4): 540–9.CrossRefGoogle ScholarPubMed
Russell, J. A., Walley, K. R., Singer, J., et al. Vasopressin versus norepinephrine infusion in patients with septic shock. N Engl J Med 2008; 358(9): 877–87.CrossRefGoogle ScholarPubMed
Ward, M., Langton, J. A.. Blood pressure measurement. Continuing Educ Anaesth Crit Care Pain 2007; 7(4): 122–6.CrossRefGoogle Scholar

Further reading

Herring, N., Paterson, D. J.. Haemodynamics: flow, pressure and resistance. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 113–20.Google Scholar
Vlachopoulos, C., O’Rourke, M., Nichols, W. W.. Principles of recording and analysis of arterial waveforms. In: McDonald’s Blood Flow in Arteries: Theoretical, Experimental and Clinical Principles, 6th edition. Boca Raton, CRC Press, 2011; 255–72.CrossRefGoogle Scholar
Denardo, S. J., Nandyala, R., Freeman, G. L., et al. Pulse wave analysis of the aortic pressure waveform in severe left ventricular systolic dysfunction. Circ Heart Fail 2010; 3(1): 149–56.CrossRefGoogle ScholarPubMed
London, G. M., Pannier, B.. Arterial functions: how to interpret the complex physiology. Nephrol Dial Transplant 2010; 25(12): 3815–23.Google Scholar
Lamia, B., Chemla, D., Richard, C., et al. Interpretation of arterial pressure wave in shock states. Crit Care 2005; 9(6): 601–6.CrossRefGoogle ScholarPubMed

Further reading

Herring, N., Paterson, D. J.. Endothelium. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 149–70.Google Scholar
Herring, N., Paterson, D. J.. The circulation and solute exchange. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 171–90.Google Scholar
Herring, N., Paterson, D. J.. Circulation of fluid between plasma, interstitium and lymph. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 191–220.Google Scholar
Woodcock, T. E.. Plasma volume, tissue oedema, and the steady-state Starling principle. BJA Education 2017; 17(2): 74–8.CrossRefGoogle Scholar
Levick, J. R., Michel, C. C.. Microvascular fluid exchange and the revised Starling principle. Cardiovasc Res 2010; 87(2): 198–210.Google Scholar
Galley, H. F., Webster, N. R.. Physiology of the endothelium. Br J Anaesth 2004; 93(1): 105–13.CrossRefGoogle ScholarPubMed
Michel, C. C.. Fluid exchange in the microcirculation. J Physiol 2004; 557(3): 701–2.CrossRefGoogle ScholarPubMed

Further reading

Herring, N., Paterson, D. J.. Haemodynamics: flow, pressure and resistance. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 113–20.Google Scholar
Cooke, K., Sharvill, R., Sondergaard, S., et al. Volume responsiveness assessed by passive leg raising and a fluid challenge: a critical review focused on mean systemic filling pressure. Anaesthesia 2018; 73(3): 313–22.CrossRefGoogle Scholar

Further reading

Singer, M., Deutschman, C. S., Seymour, C. W., et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA 2016; 315(8): 801–10.CrossRefGoogle ScholarPubMed

Further reading

Herring, N., Paterson, D. J.. Circulation of fluid between plasma, interstitium and lymph. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 191–220.Google Scholar
Pikwer, A., Akeson, J., Lindgren, S.. Complications associated with peripheral or central routes for central venous cannulation. Anaesthesia 2012; 67(1): 65–71.CrossRefGoogle ScholarPubMed

Further reading

Herring, N., Paterson, D. J.. Cardiovascular receptors, reflexes and central control. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 303–24.Google Scholar
Herring, N., Paterson, D. J.. Co-ordinated cardiovascular responses. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018: 325–42.Google Scholar
Herring, N., Paterson, D. J.. Cardiovascular responses in pathological situations. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 343–68.Google Scholar
Gutierrez, G., Reines, H. D., Wulf-Gutierrez, M. E.. Clinical review: haemorrhagic shock. Crit Care 2004; 8(4): 373–81.Google Scholar
Dutton, R. P.. Haemostatic resuscitation. Br J Anaesth 2012; 109(Suppl. 1): i39–46.Google Scholar
Boeuf, B., Poirier, V., Gauvin, F., et al. Naloxone for shock. Cochrane Database Syst Rev 2003; (4): CD004443.CrossRefGoogle Scholar

Further reading

Herring, N., Paterson, D. J.. Co-ordinated cardiovascular responses. In: Herring, N., Paterson, D. J.. Levick’s Introduction to Cardiovascular Physiology, 6th edition. Boca Raton, CRC Press, 2018; 325–42.Google Scholar
Smith, G.. Management of supraventricular tachycardia using the Valsalva manoeuvre: a historical review and summary of published evidence. Eur J Emerg Med 2012; 19(6): 346–52.CrossRefGoogle ScholarPubMed

Further reading

Burton, D. A., Stokes, K., Hall, G. M.. Physiological effects of exercise. Continuing Educ Anaesth Crit Care Pain 2004; 4(6): 185–8.Google Scholar
Agnew, N.. Preoperative cardiopulmonary exercise testing. Continuing Educ Anaesth Crit Care Pain 2010; 10(2): 33–7.CrossRefGoogle Scholar

Further reading

Chambers, D. J., Wiseley, N.. Cardiopulmonary exercise testing – a beginner’s guide to the nine-panel plot. BJA Education 2019; in press.Google Scholar
Levett, D. Z. H., Jack, S., Swart, M., et al. Perioperative cardiopulmonary exercise testing (CPET): consensus clinical guidelines on indications, organisation, conduct, and physiological interpretation. Br J Anaesth 2018; 120(3): 484–500.Google Scholar
Older, P. O., Levett, D. Z. H.. Cardiopulmonary exercise testing and surgery. Ann Am Thorac Soc 2017; 14(Suppl. 1): S74–83.CrossRefGoogle ScholarPubMed
Moran, J., Wilson, F., Guinan, E., McCormick, P., Hussey, J., Moriarty, J.. Role of cardiopulmonary exercise testing as a risk-assessment method in patients undergoing intra-abdominal surgery: a systematic review. Br J Anaesth 2016; 116(2): 177–91.CrossRefGoogle ScholarPubMed
Hartley, R. A., Pichel, A. C., Grant, S. W., et al. Preoperative cardiopulmonary exercise testing and risk of early mortality following abdominal aortic aneurysm repair. Br J Surg 2012; 99(11): 1539–46.CrossRefGoogle ScholarPubMed

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