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Chapter 1 - Establishing and Equipping a New IVF Laboratory

from Section 1 - Starting a New Laboratory and Training Protocols

Published online by Cambridge University Press:  07 August 2023

By
Alex Lagunov ,
Michael Crowe  and
Jason E. Swain
Edited by
Markus H. M. Montag  and
Dean E. Morbeck
Markus H. M. Montag
Affiliation:
ilabcomm GmbH, St Augustin, Germany
Dean E. Morbeck
Affiliation:
Kindbody Inc, New York City
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Summary

Attention to detail and robust quality control systems are essential components for a successful IVF laboratory, necessary to maintain high success rates. This not only pertains to daily laboratory operations, such as adequate staff training, monitoring of equipment function or weekly/monthly success rates, but also entails proper laboratory design and construction. A highly successful IVF laboratory requires careful consideration of layout and workflow and use of appropriate materials to avoid introducing potentially embryotoxic factors into the laboratory environment.

Keywords

equipmentdesignfacilityHVACfiltration
Type
Chapter
Information
Principles of IVF Laboratory Practice
Laboratory Set-Up, Training and Daily Operation
 , pp. 1 - 8
Publisher: Cambridge University Press
Print publication year: 2023

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References

Swain, J. and Lagunov, A. IVF incubator handling, in Standard Operational Procedures in Reproductive Medicine Laboratory and Clinical Practice, ed. Rizk, B. and Montag, M. (Boca Raton, FL: CRC Press, 2017).Google Scholar
Swain, J. E. Optimizing the culture environment in the IVF laboratory: impact of pH and buffer capacity on gamete and embryo quality. Reprod Biomed Online 2010; 21(1):6–16.CrossRefGoogle ScholarPubMed
Swain, J. E. Is there an optimal pH for culture media used in clinical IVF? Hum Reprod Update 2012; 18(3):333–9.CrossRefGoogle ScholarPubMed
Hall, J., et al. The origin, effects and control of air pollution in laboratories used for human embryo culture. Hum Reprod 1998; 13(Suppl. 4):146–55.Google Scholar
Schimmel, T., et al. Removal of volatile organic compounds from incbuators used for gamete and embryo culture. Fertil Steril 1997; 68(Suppl. 1):S165.Google Scholar
Morbeck, D. E. Air quality in the assisted reproduction laboratory: a mini-review. J Assist Reprod Genet 2015; 32(7):1019–24.Google Scholar
Heitmann, R. J., et al. Live births achieved via IVF are increased by improvements in air quality and laboratory environment. Reprod Biomed Online, 2015; 31(3):364–71.Google Scholar

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