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Volume 47 - August 2017

Contents

Page 14 of 15

Correspondence

Front Cover (OFC, IFC) and matter

  • PSM volume 47 issue 7 Cover and Front matter

  • Published online by Cambridge University Press:
    28 March 2017, pp. f1-f2
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Back Cover (IBC, OBC) and matter

  • PSM volume 47 issue 11 Cover and Back matter

  • Published online by Cambridge University Press:
    07 July 2017, pp. b1-b2
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  • PSM volume 47 issue 6 Cover and Back matter

  • Published online by Cambridge University Press:
    15 March 2017, pp. b1-b3
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Front Cover (OFC, IFC) and matter

  • PSM volume 47 issue 2 Cover and Front matter

  • Published online by Cambridge University Press:
    04 January 2017, pp. f1-f2
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Corrigenda

  • Genetic Influences on Hormonal Markers of Chronic HPA Function in Human Hair – CORRIGENDUM

  • E. M. Tucker-Drob, et al.
  • Published online by Cambridge University Press:
    09 June 2017, pp. 2738-2741
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Correspondence

  • Letter to the Editor: Virtual reality in the treatment of eating and weight disorders

  • G. Riva
  • Published online by Cambridge University Press:
    09 August 2017, pp. 2567-2568
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Original Articles

  • Paternal age at childbirth and eating disorders in offspring

  • K. N. Javaras, M. E. Rickert, L. M. Thornton, C. M. Peat, J. H. Baker, A. Birgegård, C. Norring, M. Landén, C. Almqvist, H. Larsson, P. Lichtenstein, C. M. Bulik, B. M. D'Onofrio
  • Published online by Cambridge University Press:
    03 November 2016, pp. 576-584
  • Background

    Advanced paternal age at childbirth is associated with psychiatric disorders in offspring, including schizophrenia, bipolar disorder and autism. However, few studies have investigated paternal age's relationship with eating disorders in offspring. In a large, population-based cohort, we examined the association between paternal age and offspring eating disorders, and whether that association remains after adjustment for potential confounders (e.g. parental education level) that may be related to late/early selection into fatherhood and to eating disorder incidence.

    Method

    Data for 2 276 809 individuals born in Sweden 1979–2001 were extracted from Swedish population and healthcare registers. The authors used Cox proportional hazards models to examine the effect of paternal age on the first incidence of healthcare-recorded anorexia nervosa (AN) and all eating disorders (AED) occurring 1987–2009. Models were adjusted for sex, birth order, maternal age at childbirth, and maternal and paternal covariates including country of birth, highest education level, and lifetime psychiatric and criminal history.

    Results

    Even after adjustment for covariates including maternal age, advanced paternal age was associated with increased risk, and younger paternal age with decreased risk, of AN and AED. For example, the fully adjusted hazard ratio for the 45+ years (v. the 25–29 years) paternal age category was 1.32 [95% confidence interval (CI) 1.14–1.53] for AN and 1.26 (95% CI 1.13–1.40) for AED.

    Conclusions

    In this large, population-based cohort, paternal age at childbirth was positively associated with eating disorders in offspring, even after adjustment for potential confounders. Future research should further explore potential explanations for the association, including de novo mutations in the paternal germline.

Front Cover (OFC, IFC) and matter

  • PSM volume 47 issue 16 Cover and Front matter

  • Published online by Cambridge University Press:
    14 November 2017, pp. f1-f2
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  • PSM volume 47 issue 12 Cover and Front matter

  • Published online by Cambridge University Press:
    08 August 2017, pp. f1-f2
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Correspondence

Front Cover (OFC, IFC) and matter

  • PSM volume 47 issue 14 Cover and Front matter

  • Published online by Cambridge University Press:
    13 September 2017, pp. f1-f2
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  • PSM volume 47 issue 3 Cover and Front matter

  • Published online by Cambridge University Press:
    11 January 2017, pp. f1-f2
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Correspondence

Front Cover (OFC, IFC) and matter

  • PSM volume 47 issue 15 Cover and Front matter

  • Published online by Cambridge University Press:
    09 October 2017, pp. f1-f2
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Back Cover (IBC, OBC) and matter

  • PSM volume 47 issue 12 Cover and Back matter

  • Published online by Cambridge University Press:
    08 August 2017, pp. b1-b2
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Erratum

Back Cover (IBC, OBC) and matter

  • PSM volume 47 issue 2 Cover and Back matter

  • Published online by Cambridge University Press:
    04 January 2017, pp. b1-b3
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Front Cover (OFC, IFC) and matter

  • PSM volume 47 issue 4 Cover and Front matter

  • Published online by Cambridge University Press:
    07 February 2017, pp. f1-f2
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Page 14 of 15