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Further investigation of the pathogenicity, immunogenicity and stability of precocious Eimeria acervulina

Published online by Cambridge University Press:  06 April 2009

V. McDonald  and
S. Ballingall
V. McDonald
Affiliation:
Houghton Poultry Research Station, Houghton, Huntingdon, Cambs. PE17 2DA
S. Ballingall
Affiliation:
Houghton Poultry Research Station, Houghton, Huntingdon, Cambs. PE17 2DA
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Summary

Attenuated lines of Eimeria acervulina were isolated between 62 and 72 h post-infection from the Houghton (H) strain. The inoculation of small numbers of oocysts of precocious (HP) lines gave substantial protection to Light Sussex chicks kept on litter against challenge with the virulent H strain. The precocious trait of the 72 h HP line was shown to be stable because the kinetics of oocyst production remained unaltered after 9 consecutive passages through birds in which only late developing oocysts were used for passage. The precocious 62 h HP line was subjected to further selection for 5 consecutive passages. The resultant (62 A HP) line was shown to be more attenuated than the 72 h HP line but remained capable of immunizing chicks against challenge with the H strain.

Type
Research Article
Information
Parasitology , Volume 86 , Issue 3 , June 1983 , pp. 361 - 369
Copyright
Copyright © Cambridge University Press 1983

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References

REFERENCES

Cooper, D. M. & Timms, J. R. (1972). The rearing and maintenance of breeding chickens in isolators. 1. Glassfibre isolators. Avian Pathology 1, 45–57.Google Scholar
Jeffers, T. K. (1975). Attenuation of Eimeria tenella through selection for precociousness. Journal of Parasitology 61, 1083–90.CrossRefGoogle ScholarPubMed
Krassner, S. M. (1963). Factors in host susceptibility and oocyst infectivity in Eimeria acervulina infections. Journal of Protozoology 10, 327–33.CrossRefGoogle ScholarPubMed
Long, P. L. (1972 a). Eimeria tenella: reproduction, pathogenicity and immunogenicity of a strain maintained in chick embryos by serial passage. Journal of Comparative Pathology and Therapeutics 82, 429–37.CrossRefGoogle ScholarPubMed
Long, P. L. (1972 b). Eimeria mivati: reproduction, pathogenicity and immunogenicity of a strain maintained in chick embryos by serial passage. Journal of Comparative Pathology and Therapeutics 82, 439–45.CrossRefGoogle ScholarPubMed
Long, P. L. & Millard, B. J. (1979). Eimeria: further studies on the immunisation of young chickens kept in litter pens. Avian Pathology 8, 213–28.CrossRefGoogle ScholarPubMed
Long, P. L. & Rowell, J. G. (1958). Counting oocysts of chicken coccidia. Laboratory Practice 7, 515–19.Google Scholar
McDonald, V., Ballingall, S. A. & Shirley, M. W. (1982). A preliminary study of the nature of infection and immunity in chickens given an attenuated line of Eimeria acervulina. Parasitology 84, 21–30.CrossRefGoogle ScholarPubMed
McDougald, L. R. & Jeffers, T. K. (1976). Eimeria tenella: (Sporozoa: Coccidia): gametogony following a single asexual generation. Science 192, 258–9.CrossRefGoogle ScholarPubMed
Norton, C. C. & Joyner, L. N. (1980). Studies with Eimeria acervulina and Eimeria mivati: pathogenicity and cross-immunity. Parasitology 81, 315–23.CrossRefGoogle ScholarPubMed
Rose, M. E. (1967). The influence of host on infection with Eimeria tenella. Journal of Parasitology 53, 924–9.CrossRefGoogle ScholarPubMed
Shirley, M. W. (1980). Eimeria necatrix: the development and characteristics of an egg-adapted (attenuated) line. Parasitology 81, 525–35.CrossRefGoogle ScholarPubMed