Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-848d4c4894-hfldf Total loading time: 0 Render date: 2024-05-09T13:54:58.682Z Has data issue: false hasContentIssue false

Chapter 33 - Contraception in Women with Polycystic Ovary Syndrome

from Section 2A - Sexual and Reproductive Healthcare: Contraception

Published online by Cambridge University Press:  16 January 2024

By
Christina I. Messini ,
George Anifandis ,
Alexandros Daponte  and
Ioannis E. Messinis
Edited by
Johannes Bitzer  and
Tahir A. Mahmood
Johannes Bitzer
Affiliation:
University Women's Hospital, Basel
Tahir A. Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
Get access

Summary

Up to now, there is no comprehensive pathophysiological explanation for PCOS. Its heterogeneity may reflect multiple mechanisms which in individual women are not necessarily involved simultaneously but help explain the close relation of metabolic–reproductive circuitry. Ovarian androgen excess and anovulation are key features of the disorder.

Type
Chapter
Information
Textbook of Contraception, Sexual and Reproductive Health , pp. 204 - 207
Publisher: Cambridge University Press
Print publication year: 2024

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Villarroel, C, López, P, Merino, PM et al. Hirsutism and oligomenorrhea are appropriate screening criteria for polycystic ovary syndrome in adolescents. Gynecol Endocrinol. 2015;31:625–9.CrossRefGoogle ScholarPubMed
http://bit.ly/3Y0jGpe.Google Scholar
Ibáñez, L, Oberfield, SE, Witchel, S et al. An international consortium update: Pathophysiology, diagnosis, and treatment of polycystic ovarian syndrome in adolescence. Horm Res Paediatr. 2017;88:371–95.CrossRefGoogle Scholar
www.nhs.uk/conditions/acne/treatment.Google Scholar
https://bit.ly/40qrtyn.Google Scholar
Dos Santos, IK, Ashe, MC, Cobucci, RN et al. The effect of exercise as an intervention for women with polycystic ovary syndrome: A systematic review and meta-analysis. Medicine (Baltimore). 2020;99:e19644.CrossRefGoogle ScholarPubMed
Shang, Y, Zhou, H, Hu, M, Feng, H. Effect of diet on insulin resistance in polycystic ovary syndrome. J Clin Endocrinol Metab. 2020;105:dgaa425.CrossRefGoogle ScholarPubMed
Yen, H, Chang, YT, Yee, FJ, Huang, YC. Metformin therapy for acne in patients with polycystic ovary syndrome: A systematic review and meta-analysis. Am J Clin Dermatol. 2020.CrossRefGoogle Scholar
Kim, CH, Chon, SJ, Lee, SH. Effects of lifestyle modification in polycystic ovary syndrome compared to metformin only or metformin addition: A systematic review and meta-analysis. Sci Rep. 2020;10:7802.CrossRefGoogle ScholarPubMed
Gariani, K, Hugon-Rodin, J, Philippe, J, Righini, M, Blondon, M. Association between polycystic ovary syndrome and venous thromboembolism: A systematic review and meta-analysis. Thromb Res. 2020;185:102–8.CrossRefGoogle ScholarPubMed
Ignatov, A, Ortmann, O. Endocrine risk factors of endometrial cancer: Polycystic ovary syndrome, oral contraceptives, infertility, Tamoxifen. Cancers (Basel). 2020;12:1766.CrossRefGoogle ScholarPubMed
Costello, M, Shrestha, B, Eden, J, Sjoblom, P, Johnson, N. Insulin-sensitising drugs versus the combined oral contraceptive pill for hirsutism, acne and risk of diabetes, cardiovascular disease, and endometrial cancer in polycystic ovary syndrome. Cochrane Database Syst Rev. 2007;(1):CD005552.Google ScholarPubMed
Domecq, JP, Prutsky, G, Mullan, RJ et al. Adverse effects of the common treatments for polycystic ovary syndrome: A systematic review and meta-analysis. J Clin Endocrinol Metab. 2013;98:4646–54.Google ScholarPubMed
Menshawy, A, Ismail, A, Abdel-Maboud, M et al. J Gynecol Obstet Hum Reprod. 2019;48:763–70.CrossRefGoogle Scholar
Amiri, M, Ramezani Tehrani, F, Nahidi, F, Kabir, A, Azizi, F. Comparing the effects of combined oral contraceptives containing progestins with low androgenic and antiandrogenic activities on the hypothalamic-pituitary-gonadal axis in patients with polycystic ovary syndrome: Systematic review and meta-analysis. JMIR Res Protoc. 2018;7:e113.CrossRefGoogle ScholarPubMed
Amiri, M, Ramezani-Tehrani, F, Nahidi, F, Kabir, A, Azizi, F. Effects of oral contraceptives on metabolic profile in women with polycystic ovary syndrome: A meta-analysis comparing products containing cyproterone acetate with third generation progestins. Metabolism. 2017;73:22–35.CrossRefGoogle ScholarPubMed
Amiri, M, Kabir, A, Nahidi, F, Shekofteh, M, Ramezani–Tehrani, F. Effects of combined oral contraceptives on the clinical and biochemical parameters of hyperandrogenism in patients with polycystic ovary syndrome: A systematic review and meta-analysis. Eur J Contracept Reprod Health Care. 2018;23:64–77.CrossRefGoogle ScholarPubMed
Silva-Bermudez, LS, Toloza, FJK, Perez-Matos, MC et al. Effects of oral contraceptives on metabolic parameters in adult premenopausal women: A meta-analysis. Endocr Connect. 2020;9:978–98.CrossRefGoogle ScholarPubMed
Naderpoor, N, Shorakae, S, de Courten, B et al. Metformin and lifestyle modification in polycystic ovary syndrome: Systematic review and meta-analysis. Hum Reprod Update. 2015;21:560–74.CrossRefGoogle ScholarPubMed
Barrionuevo, P, Nabhan, M, Altayar, O et al. Treatment options for hirsutism: A systematic review and network meta-analysis. J Clin Endocrinol Metab. 2018;103:1258–64.CrossRefGoogle ScholarPubMed
Conway, G, Dewailly, D, Diamanti-Kandarakis, E et al. The polycystic ovary syndrome: A position statement from the European Society of Endocrinology. Eur J Endocrinol. 2014;171:P1–29.CrossRefGoogle ScholarPubMed
Bhattacharya, SM, Jha, A. Comparative study of the therapeutic effects of oral contraceptive pills containing desogestrel, cyproterone acetate, and drospirenone in patients with polycystic ovary syndrome. Fertil Steril. 2012;98:1053–9.CrossRefGoogle ScholarPubMed
Legro, RS, Arslanian, SA, Ehrmann, DA et al. Diagnosis and treatment of polycystic ovary syndrome: An Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2013;98:4565–92.CrossRefGoogle ScholarPubMed
Teede, HJ, Misso, ML, Costello, MF et al. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Fertil Steril. 2018;110:364–79.CrossRefGoogle ScholarPubMed
http://bit.ly/3X8i9vX.Google Scholar
Teede, H, Tassone, EC, Piltonen, T et al. Effect of the combined oral contraceptive pill and/or metformin in the management of polycystic ovary syndrome: A systematic review with meta-analyses. Clin Endocrinol (Oxf). 2019;91:479–89.CrossRefGoogle ScholarPubMed
Mendoza, N, Simoncini, T, Genazzani, AD. Hormonal contraceptive choice for women with PCOS: A systematic review of randomized trials and observational studies. Gynecol Endocrinol. 2014;30:850–60.CrossRefGoogle ScholarPubMed
Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004;19:41–7.Google Scholar
World Health Organization. WHO guidelines: Medical eligibility criteria for contraceptive use. 5th edition. Geneva: World Health Organization, 2015. www.who.int/publications/i/item/9789241549158.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×