Skip to main content Accessibility help
×
Home
Hostname: page-component-7f7b94f6bd-w6m4b Total loading time: 0.955 Render date: 2022-06-30T14:20:25.929Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "useRatesEcommerce": false, "useNewApi": true } hasContentIssue true

Chapter 14 - Chorionic gonadotropin and luteinizing hormone supplementation during ovarian stimulation

from Section 4: - Non-conventional forms used during ovarian stimulation

Published online by Cambridge University Press:  05 August 2011

Mohamed Aboulghar
Affiliation:
Cairo University and the IVF-ET Center
Botros Rizk
Affiliation:
University of South Alabama
Get access

Summary

This chapter summarizes evidence related to the potential benefits and drawbacks of the use of luteinizing hormone (LH) activity in the management of anovulation and assisted reproduction therapy (ART). The specific contribution of LH and human chorionic gonadotropin (hCG) to the LH activity content of human menopausal gonadotropin (hMG) preparations is variable. Expression of the LH/CG receptor in granulosa cells is dependent upon follicle stimulating hormone (FSH) stimulation and enhanced by estrogen. In addition to FSH stimulation, proper estrogen concentration permits the achievement of optimal LH/CG receptor levels in late-follicular phase granulosa cells. Both ovulation induction (OI) and controlled ovarian stimulation (COS) are conducted with gonadotropin preparations containing FSH with or without LH activity. The administration of CG is an effective and cost-effective means to provide LH activity, as both LH and CG interact with the same gonadal receptors.
Type
Chapter
Information
Ovarian Stimulation , pp. 151 - 161
Publisher: Cambridge University Press
Print publication year: 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×