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The identification of somatic growth, through reference curves, can be used to create strategies and public policies to reduce public health problems such as malnutrition and obesity and to identify underweight, overweight and obesity, taking into account the variability of physical and of human development characterized by intra and interpopulation heterogeneity. The purpose of this systematic review was to identify studies providing reference growth curves for weight status (underweight, overweight or obesity) in children and adolescents. A systematic search was conducted in CINAHL; LILACS; PubMed ScienceDirect; Scopus; SPORTDiscus; SciELO; Web of Science. Manual searches were also carried out in gray literature (Google scholar) in order to find possible studies that were not retrieved by the search strategy. Data were extracted by two independent reviewers, and consensus was verified between them. To assess the risk of bias/methodological quality of studies, the National Institutes of Health (NIH) Quality Assessment Tool for Observational Cohort and Cross-sectional Studies (NHLBI) was used. Overall, 86 studies that met the inclusion criteria were included (cross-sectional and longitudinal). Through the values of reference growth curves for the identification of underweight, overweight and obesity, it was possible to verify that there is great variability among percentiles for the identification of underweight, overweight and obesity. The most prevalent percentiles for underweight were P3 and P5; for overweight, the most prevalent was P85 and the most prevalent percentiles for obesity were P95 and P97. The most prevalent anthropometric indicators were Body Mass Index (BMI), Waist Circumference (WC), Body Mass (BM) for age and height for age. Conclusion: The optimal growth must be reached, through the standard growth curves, but that the reference curves demonstrate a cut of the population growth, raising possible variables that can influence the optimal growth, such as an increase in the practice of physical activities and an awareness of proper nutrition.
Methionine (MET) supplementation is a current strategy to achieve shrimp requirement. Notwithstanding, the efficiency of the precisely formulated feeds can be diminished since shrimps are slow eaters and masticate feed externally that results in nutrient leaching. In this regard, a methionine dipeptide (DL-methionyl DL-methionine) benefits the feed industry by reducing MET water solubility while increasing its bioavailability. Therefore, the effects of feeding whiteleg shrimp (Penaeus vannamei) with increasing levels of methionine dipeptide were evaluated on zootechnical performance and methionine-, immune- and antioxidant-related pathways. A 74 d growth trial was conducted by feeding a control diet and four diets supplemented with AQUAVI® Met-Met at 0·08, 0·12, 0·24 and 0·32% of DM. Diet digestibility, body amino acids (AA) composition and nitrogen metabolites, metabolic enzymes, oxidative status and gene expression were evaluated. It can be concluded that graded dietary increase of methionine dipeptide up to 0·24 % for 74 d translated in significant gains on the growth performance, feed efficiency, nutrient and nitrogen gain and shrimp survival. Moreover, it was showed that Met-Met dietary spare leads to an improvement of free-AA pool and nitrogen metabolites concentration and reduces the signs of oxidative stress. Finally, in a closer look to the MET-related pathways passive to be altered by Met-Met spare, a clear modulation of the described antioxidant and cell proliferation routes was detected.
Tail biting is a major problem in modern pig (Sus scrofa) production and results in a reduction of animal welfare and productive performance. Biting behaviour has been shown to be decreased by the use of enrichment objects. In this study, 108 pigs housed in a room with 12 pens were observed and a sequence of seven different enrichment materials was tested. Gilts and barrows were housed together and received a new enrichment object each week starting from three different points in the fattening period, ie 20, 40 or 70 kg bodyweight. Toy-contact and biting-penmate behaviour were observed during one hour at day of introduction and five days later. A continuous sequence of seven enrichment objects reduced biting-penmate behaviour and the number of wounds compared to providing only a single toy (chain). This study also confirmed that not every object was feasible as an enrichment object for growing pigs. Generally, the highest toy contact was observed together with the highest biting-penmate behaviour. Most toy-contact and biting-penmate behaviour was observed between 20 and 40 kg bodyweight and was decreasing over age. Providing a sequence of toys for the first time induced toy-contact behaviour while reducing bitingpenmate behaviour but decreased after applying the same sequence for the second or third time. The presence of a single chain or a sequence of different toys had no effect on growth and feed conversion. The ideal sequence should maintain toy-contact behaviour without competition in order to avoid biting-penmate behaviour and reduced animal welfare.
This article focuses on the role of unionised members of parliament. While unions have a direct effect on the labour market via wage negotiations, they often also take part in political debates. In many countries, significant shares of the members of parliament are also members of a trade union. However, up to now little empirical evidence is available on the extent to which unionised members of parliament try to achieve union-specific goals and thereby influence the macroeconomic conditions of an economy. A recent study for Germany comes to the conclusion that union members in the Bundestag cannot be seen as the parliamentary arm of the trade unions. However, we present contradicting empirical results by showing that, in Germany at least, the degree of unionisation of parliamentary members has a negative impact on economic growth and increases inflation, while unemployment remains unaffected.
Governments’ economic policies need to be based on a coherent view of the role of innovation and productivity in sustaining growth. This article analyses advice on fostering innovation from Australia’s main statutory economics adviser, the Productivity Commission. It argues that the Productivity Commission’s comprehensive 2007 report, Public Support for Science and Innovation, contributed to a policy vacuum hampering government support for innovation for nearly a decade. First, within the Productivity Commission’s understanding of innovation was a contradiction between its required policy targeting criteria and the impossibility of meeting these criteria. Second, the resulting stance on innovation policy was at odds with research and theory on the drivers of innovation and hence growth – particularly innovation systems theories and those based on evolutionary economics. The ensuing innovation policy vacuum suggests that the Productivity Commission placed the abstract ideological ‘purity’ of neoclassical economic theory above empirical exploration of how government can best support Australia’s future economic development. Since late 2015, moves to fill this policy vacuum have included a Senate inquiry, a government department restructure, and the creation of a new Innovation and Science statutory advisory board. Whether these initiatives foster sustained innovation will depend on the extent to which they adopt approaches based on innovation systems or evolutionary economics, and transcend the static neoclassical mindset espoused by the Productivity Commission.
This essay is a review of and tribute to the life and contributions of Nina Shapiro, who passed away this year. Shapiro was an American Post-Keynesian economist, who was a bridge figure in radical economics, connecting Marx to Keynes, Schumpeter to Kaldor, the behavior of the firm to the dynamics of the macroeconomy, and the process of innovation to the organization of production and accumulation. She was seminal to important moments in the history of radical economics in the US, including the formation of the Hegel-inspired journal Social Concept in the 1980s and the Rutgers University’s Post-Keynesian circle in the 1980s and 1990s. Shapiro’s deeply philosophical and dialectical approach to firm behavior, innovation, and business cycles led her to theorize the “revolutionary character” of Post-Keynesian economics and to formulate a critique of the competitive neoclassical firm which, she argued, is at odds with the logic of capitalism in which firms seek to make profit and grow.
Broiler breeder chickens are commonly reared under strict feed-restriction regimes to reduce obesity-induced health and fertility problems during adult life, and are assumed to experience a reduced welfare due to the resulting hunger. In these conditions, feed competition could influence the growth rate, so that the individuals falling behind in growth would experience more stress and hunger. We hypothesised that these chickens are poor competitors due to a reactive coping style and experience a further reduced welfare situation before size-sorting (‘grading’) at four weeks of age. Our results from open field, tonic immobility and home pen activity monitoring show signs of lower fear and higher home-pen activity levels in smaller hens and do not support the idea of reactive coping. H/L ratios of smaller hens were also found to be lower, indicating less stress in these birds. Dissections of smaller and larger four-week breeder hens may offer an explanation in the form of a relatively larger gastrointestinal tract in smaller birds. We argue that this is a form of habituation to restricted feeding, offering these birds a physiological stress coping mechanism, and that low early growth rate may not always be a sign of poorer welfare in broiler breeders.
We are now close to reaching what climate scientists advise is a ‘tipping point’ when the injuries we have visited on the planet will become self-reinforcing and produce an ecosystem that is alien to human life. The mal-distribution of consumption within and between nations is a major reason why there is little agreement on appropriate remedial action. Ensuring planetary survival while reducing inequity is made the more difficult, because the richest one-seventh of the world’s population has already reached consumption levels beyond the capacity of the planetary ecosystem to accommodate it.
The rapid liberalisation of trade policies since the 1990s has brought additional attention to the role of trade as an engine of economic growth. Although an abundant literature addresses the relationship between openness and economic growth, the real effect of trade liberalisation is still ambiguous and undetermined. Most previous studies have ignored the selection effects of strict labour regulations on international trade. The main objective of this study is to measure the role of labour regulations in moderating the contribution of trade to economic growth among 30 Organisation for Economic Co-operation and Development countries for the period 2006–2013. In doing so, we employ a one-step Generalised Method of Moments system estimation method. Our results reveal that openness to trade does not have a robust and significant effect on growth. However, the interaction of openness with strict labour regulations enhances the contributions of trade to growth.
This paper critically examines the key empirical evidence used to support the fiscal consolidation argument, complemented by a brief assessment of the limitations of the analytical foundation of the growth promoting benefits of the fiscal consolidation thesis. It also reviews the evidence on the debt-growth relationship at some length. It finds that the negative relationship between debt and GDP growth is influenced by outliers or exceptionally high debt-GDP ratios. It also points out that the composition of public debt matters. Additionally, the debt-GDP relationship appears to be non-linear—positive first and turning to negative, but there is considerable variation in the estimated turning or ‘tipping’ point, which is not helpful as a policy guide. Historical evidence does not lend support to the concerns that the current situation is likely to cause rapid upward spiraling of public indebtedness. Finally, the argument that fiscal consolidation is possible without adversely affecting growth is not based on robust empirical evidence. This conclusion is reinforced by a succinct overview of some country-specific experiences (Denmark, Ireland and United States).
Growth failure in infants born with CHD is a persistent problem, even in those provided with adequate nutrition.
Objective:
To summarise the published data describing the change in urinary metabolites during metabolic maturation in infants with CHD and identify pathways amenable to therapeutic intervention
Design:
Scoping review.
Eligibility criteria:
Studies using qualitative or quantitative methods to describe urinary metabolites pre- and post-cardiac surgery and the relationship with growth in infants with CHD.
Sources of evidence:
NICE Healthcare Databases website was used as a tool for multiple searches.
Results:
347 records were identified, of which 37 were duplicates. Following the removal of duplicate records, 310 record abstracts and titles were screened for inclusion. The full texts of eight articles were reviewed for eligibility, of which only two related to infants with CHD. The studies included in the scoping review described urinary metabolites in 42 infants. A content analysis identified two overarching themes of metabolic variation predictive of neurodevelopmental abnormalities associated with anaerobic metabolism and metabolic signature associated with the impact on gut microbiota, inflammation, energy, and lipid digestion.
Conclusion:
The results of this scoping review suggest that there are considerable gaps in our knowledge relating to metabolic maturation of infants with CHD, especially with respect to growth. Surgery is a key early life feature for CHD infants and has an impact on the developing biochemical phenotype with implications for metabolic pathways involved in immunomodulation, energy, gut microbial, and lipid metabolism. These early life fingerprints may predict those individuals at risk for neurodevelopmental abnormalities.
This chapter presents the first annual estimates of Liberia’s economic performance based on archival data since its declaration of independence in 1847 until 2000. A lack of easily accessible data has been one of the main reasons why Liberia has appeared so infrequently in comparative work in African economic history. The collection of data was a central component of imperial governance, and historians have relied on the legacy of those efforts; independent states had both different incentives and, often, lower capacity. However, this chapter shows that it is possible to reconstruct through qualitative records annual estimates of trade and government finances dating back to Liberia’s foundation. These estimates then form the foundation for the first series of historical national accounts which can be used to compare Liberia to other countries. They show the Liberian economy during the late nineteenth and early twentieth centuries, when many other African economies were growing. A period of rapid economic growth began during the 1930s, which continued for much of the next half century before a catastrophic reversal from 1980. This chapter sets the stage for the more thematic chapters to follow.
Here we uncover the mysteries of the baby as it develops in the womb, discussing how fetal development is controlled. We give insights into aspects of pregnancy not widely known, from the fetus starting to breathe months before it is born, to the question of whether it sleeps – and dreams. We discuss the ways in which information about the mother’s life and her environment affect the baby’s development. Although birth may seem the first major milestone for a baby, we emphasise that many other milestones have been passed before that, inside the womb, out of sight but over which parents can have substantial influence. We give insights into new discoveries about how the organs of the fetal body develop in prediction of the world in which that individual ‘expects’ to live, and what happens when the prediction turns out to be wrong. The idea that the fetus is preparing for life after birth will get the reader thinking about the long-term consequences of the way a fetus develops. Each of us is unique as a result of our development – and nobody is perfect. Our unique development starts from the moment of conception, which introduces the next chapter on sex.
This chapter provides historical background on Asia, amid talks of an Asian twenty-first century. We show that Asia’s resurgence has been based on models that differ substantively from those of capitalist development in Europe and North America, not least through the heavy reliance on the state. Further, they have had many common features, not least being centred on the pervasive use of connections – familial, commercial and political. We term these networks as the connections world. Whilst this world has been supportive to growth and development, it contains major fallibilities. These include cronyism and its consequences – high inequality and corruption. In addition, the connections world breeds market power which impairs efficiency and innovation. The resulting structure of the economy also holds back the creation of good jobs. Much of the connections world is also associated with autocracy or heavily managed democracies and this introduces risks of instability. As such, the broad model that has helped Asia grow so strongly is less likely to be so supportive in future. Rethinking the connections world will be required – not an easy task given strongly embedded and resilient foundations.
A central feature of modern Asia that trumps differences in economic and political systems is the web of close relationships running between and within business and politics; the connections world. These networks facilitate highly transactional interactions yielding significant reciprocal benefits. Although the connections world has not as yet seriously impeded Asia's economic renaissance, it comes with significant costs and fallibilities. These include the creation and entrenchment of huge market power and the attenuation of competition. They in turn hold back the growth in productivity and innovation that will be essential for further development. The connections world also breeds massive inequalities that may culminate in political instability. The authors argue that if Asia's claim to the 21st century is not to be derailed, major changes must be made to policy and behaviour so as to cut away the foundations of the connections world and promote more sustainable economic and political systems.
The current study aims to describe the consumption of ultra-processed foods, from 2 to 4 years old, and evaluate its association with growth outcomes during the same period. It is a prospective cohort study using data from the 2015 Pelotas-Brazil Birth Cohort. Outcomes assessed at the 2- and 4-year-old follow-ups were BMI-for-age Z-score and length/height-for-age Z-score. The exposure was a score of ultra-processed food consumption calculated at each follow-up by summing up the positive answers for the consumption of nine specific items/subgroups of ultra-processed foods: (i) instant noodles; (ii) soft drink; (iii) chocolate powder in milk; (iv) nuggets, hamburger or sausages; (v) packaged salty snacks; (vi) candies, lollipops, chewing gum, chocolate or jelly; (vii) sandwich cookie or sweet biscuit; (viii) juice in can or box or prepared from a powdered mix and (ix) yogurt. Crude and adjusted analyses between the score of ultra-processed foods and the outcomes were run using generalised estimating equations. Prevalence of consumption of ultra-processed foods increased from 2 to 4 years old, for all evaluated items/subgroups, except yogurt. In prospective analyses, higher scores of ultra-processed food consumption were associated with higher BMI-for-age Z-score and lower length/height-for-age Z-score, after adjustment for confounders. Ultra-processed food consumption, measured using a short questionnaire with low research burden, increased from 2 to 4 years old and was related to deleterious growth outcomes in early childhood. These results reinforce the importance of avoiding the consumption of these products in childhood to prevent the double burden of malnutrition and non-communicable chronic diseases throughout the life.
It is generally agreed in social scientific scholarship that federal institutions promote efficiency and economic growth in the modern world. This chapter asks whether the same case can be made for antiquity. Political scientists and economists recognize three major mechanisms by which federal institutions promote economic growth: decentralized fiscal decision-making that incentivizes the adoption of policies enhancing local economies; high redistributive capacity that can direct resources where they are most needed; and reliance on local revenues that encourages local governments to invest in public goods that enhance market activity. Although there is some evidence to suggest that these each of these institutional arrangements existed in antiquity, it is argued that there is simply not enough evidence to demonstrate that they did, in fact, lead to economic growth in the ways that the modern theory of fiscal federalism predicts. The chapter then explores several different ways in which federal institutions may have led to economic growth in the case of Greek antiquity – regional property rights and the pooling of complementary resources, shared currency, and enhanced diplomatic power – while cautioning that there is no evidence to prove that there was a causal link between any of these practices and actual economic growth.
Although significant progress has been made in dealing with ancient economies through the establishing of new methodological approaches (like the New Institutional Economics), old-school Political Economy still plays an important role. It endeavours among other things to describe and evaluate the causes which lead to economic growth, thereby including factors which cannot be subsumed under the category of ‘institutions’ (exclusively focused on by the NIE) like demography or climate. Recently, this traditional approach has been intensively adopted to explain and measure the growth of ancient Greek economies between the ninth and fourth centuries, today viewed as an established fact in contrast to the older consensus, which was characterised by scepticism regarding the capability of ancient societies to generate sustainable growth. This chapter presents the most important factors that were (supposedly) conducive to growth and describes and their mutual interplay and interferences. In a further section, some methodological and empirical problems of the way 'ancient growth' is quantified in contemporary research are discussed. In a final section, some thoughts are offered on geo-economic factors, assumed by the author to have had a decisive impact in bringing about 'growth' or concentrations of wealth in some areas and milieus.
A trite, if apt, metaphor for the American health care and insurance system is a battleship that has been sailing in a particular direction for many years, with many of us as free riders in a direction we do not prefer. That direction is characterized by spending growth that outpaces virtually any other sectoral trend in the economy, and by quality and outcome measures that, at best, improve little and, at worst, deteriorate. The battleship takes up 18 percent of gross domestic product (GDP), furnishes employment to nearly 15 percent of the workforce, and consumes a large share of federal and state governmental budgets (Figure 2.1). Even if we could figure out how to cut the power, this dreadnought would continue to coast in the same direction for the foreseeable future. The obvious conclusion is that it has been and will continue to be hard to turn the vessel to go in a different direction. As of this writing, the novel coronavirus pandemic has affected the use of care as well, putting many “normal” services on hold to accommodate sick patients. And while it is too early to conclusively confirm the effect of the pandemic on spending trends, there is likely to be an effect (although even the direction is not known). Once the pandemic stabilizes, consumption of health care services will probably not return exactly to past behaviors, but there will be a strong tendency to slide back. What might help to avoid doing so, and most importantly, what evidence can be currently offered or generated to support efforts to change course?
In practice, firms face a number of scarce innovation projects. They choose one towards which to direct their effort, but do not coordinate these choices. This gives rise to coordination frictions. This paper develops an expanding-variety endogenous growth model to study the implications of these frictions for growth and welfare. We find that the coordination failure generates a number of foregone innovations and reduces the economy-wide research intensity. Both effects decrease the growth rate. This creates a general equilibrium effect that endogenously amplifies the fraction of wasteful simultaneous innovation. Furthermore, formalizing the coordination frictions uncovers a novel link between the “stepping on toes” and “standing on shoulders” externalities—their magnitudes are endogenously determined through the ratio of firms to innovation projects. We find that the “stepping on toes” externality is larger for all parameter values.