CaSiO3 powders were prepared from an ethanol solution dissolving Ca(NO3)2 · 4H2O and Si(OC2H5)4 by the coprecipitation method using various concentrations of NaOH as precipitants. Some Na component remained in the precipitates without washing and strongly affected the characteristics of the resultant powders, but the Na residue was removed by a washing treatment. The precipitate prepared by using 0.33 mol/l of NaOH and twice-washing contained the lowest amount of Na residue. It was calcined at 500 and 900 °C, respectively, to crystallize CaSiO3 phase and ground by a planetary potmill. The ground CaSiO3 powder was sintered to about 89% theoretical density by firing at 1400 °C. By soaking the CaSiO3 sintered bodies in simulated body fluid (SBF) solution for various times, an hydroxylapatite (HAp) layer formed as aggregates of ball-like particles on the surface of the CaSiO3 sintered bodies after soaking for a short period; thereby, the CaSiO3 ceramics is suggested to have very good biocompatibility.