We present an overview of the Middle Ages Galaxy Properties with Integral Field Spectroscopy (MAGPI) survey, a Large Program on the European Southern Observatory Very Large Telescope. MAGPI is designed to study the physical drivers of galaxy transformation at a lookback time of 3–4 Gyr, during which the dynamical, morphological, and chemical properties of galaxies are predicted to evolve significantly. The survey uses new medium-deep adaptive optics aided Multi-Unit Spectroscopic Explorer (MUSE) observations of fields selected from the Galaxy and Mass Assembly (GAMA) survey, providing a wealth of publicly available ancillary multi-wavelength data. With these data, MAGPI will map the kinematic and chemical properties of stars and ionised gas for a sample of 60 massive ( ${>}7 \times 10^{10} {\mathrm{M}}_\odot$ ) central galaxies at $0.25 < z <0.35$ in a representative range of environments (isolated, groups and clusters). The spatial resolution delivered by MUSE with Ground Layer Adaptive Optics ( $0.6-0.8$ arcsec FWHM) will facilitate a direct comparison with Integral Field Spectroscopy surveys of the nearby Universe, such as SAMI and MaNGA, and at higher redshifts using adaptive optics, for example, SINS. In addition to the primary (central) galaxy sample, MAGPI will deliver resolved and unresolved spectra for as many as 150 satellite galaxies at $0.25 < z <0.35$ , as well as hundreds of emission-line sources at $z < 6$ . This paper outlines the science goals, survey design, and observing strategy of MAGPI. We also present a first look at the MAGPI data, and the theoretical framework to which MAGPI data will be compared using the current generation of cosmological hydrodynamical simulations including EAGLE, Magneticum, HORIZON-AGN, and Illustris-TNG. Our results show that cosmological hydrodynamical simulations make discrepant predictions in the spatially resolved properties of galaxies at $z\approx 0.3$ . MAGPI observations will place new constraints and allow for tangible improvements in galaxy formation theory.

Using data from The National Epidemiologic Survey on Alcohol and Related Conditions, the strength of social networks and the association of self-reported health among American Indians and Alaska Natives (AI/AN) and non-Hispanic Whites (NHW) were compared. Differences in social network–health relationships between AI/ANs and NHWs were also examined. For both groups, those with fewer network members were more likely to report fair or poor health than those with average or more network members, and persons with the fewest types of relationships had worse self-reported health than those with the average or very diverse types of relationships. Furthermore, small social networks were associated with much worse self-reported health in AI/ANs than in NHWs.

The recent epidemic of acute glomerulonephritis in Trinidad had two peaks, separated by an interval of about 6 months.

Evidence is presented that there were in fact two successive but overlapping epidemics, the first due to streptococci of provisional M-type 55, and the second to streptococci of M-type 49.

Twenty-four reciprocal crosses between two green and six chimera cultivars, containing respectively normal green and mutant white plastids in their germ layers, were analysed for their segregation patterns of green, variegated and white embryos, and for their fertility data.

Analysis of variance of fertility data showed that W × G crosses were generally less fertile than the reciprocal G × W crosses, but this was not correlated with selection against any particular class of embryo.

Analysis of segregation patterns showed that they were essentially the same with a constant female and varying male parent, but change the female and the pattern could be radically altered. The six different mutant females with both constant green males could be arranged in a sequence in which white plastids were increasingly successful, and white and variegated embryos increasingly frequent. A similar sequence was demonstrated with three green females and two constant white males. It was concluded that the major control of plastid inheritance was determined by the female nuclear and plastid genotypes, with the male having only a minor, modifying influence even when male plastids were more successfully transmitted than female ones.

The very low frequencies of variegated embryos in some crosses led to a rejection of the classical hypothesis of sorting-out from mixed cells, and its replacement by the hypothesis that pure green or pure white embryos arise by the replication of only one plastid at a time, whereas variegated embryos arise by replication of both plastids.

Land resources are scarce in Mauritius and to fulfil the export quota sugarcane (Saccharum hybrids) has to be grown in marginal areas which are not conducive to optimal growth. In order to increase overall productivity there is a need to breed and select sugarcane varieties specifically adapted to the extremely dry and extremely wet areas. In this study, 154 genotypes representing four families were planted in a randomized complete block design at two sites. The genotypes were replicated at the two sites and evaluated in the plant cane and first ratoon crops. Family × environment and genotype × environment interactions were determined using the mixed model analysis of variance. Significant differences between families, genotypes and environments were found in stalk height, stalk diameter, industrial recoverable sucrose % cane (IRSC) and cane yield per hectare in tonnes (TCH). The genotype × environment interaction was significant for stalk height, stalk number, stalk diameter, sucrose content, TCH, tonnes sugar per hectare (TSH) and kilobrix (parameter used for selection in the preliminary phase of the selection programme at the Mauritius Sugar Industry Research Institute) in both plant cane and first ratoon crops indicating that the relative performance of the genotypes is not consistent across the environments for these characters. The family × environment interaction was found to be significant for cane and sugar yields whereas it was not significant for field Brix in either the plant cane or the ratoon crops. This showed that, for the parameter Brix, the relative performance of the families is similar in both environments and there is no need to replicate in more than one environment. The environmental sensitivities measured with respect to sugar yield showed that families and genotypes with nearly equal means over all environments displayed inconsistent performances. Differences in the sensitivities of the different families and genotypes were observed and some of the family × environment and genotype × environment interactions could be ascribed to them. The results also suggest that mass selection could be more effective than family selection and selection for each specific environment is advisable.

Plutarch's excerpt of Ctesias' version of the death of Cyrus makes fascinating reading. Although Ctesias has an unenviable reputation among scholars from antiquity onwards for fabrication and self-promotion, his description of the effects of trauma to the temple match well the clinical signs listed in a modern study of such injuries. Since he was a doctor from a family of doctors, this is not surprising, but it does suggest that his account here can be relied upon.

We report on the first established case of identical twinning in birds. The occurrence, genetic identity and subsequent development of identical emu (Dromaius novaehollandiae) twins is described, and comparisons drawn with single chicks hatched in the same season. The twin-bearing egg, significantly larger than any other egg in the same clutch, was artificially incubated and hatching assistance was necessary. At hatching the female twins were small, but their combined weight approximated that of a single chick from an egg of equivalent weight, and by 18 months of age they were near average in size. DNA analysis of blood collected from the twins showed a complete match with 22 bands per sample larger than 3.8 kb. The estimated probability of this occurring by chance was 1.0×10-13 in two unrelated emu and 1.0×10-6 in siblings, indicating a high probability that the twins were identical.

Perched water zones have been identified in the fractured, welded tuff in the semi-arid to arid environments of Yucca Mountain, Nevada and near Superior, Arizona. An understanding of the formation of such zones is necessary in order to predict where future perched water might form at Yucca Mountain, the proposed site of a high-level nuclear waste repository. The formation or growth of a perched zone near a repository is one of the factors to be considered in the risk assessment of the Yucca Mountain site.

The Apache Leap Research Site near Superior, Arizona is a natural analog to the Yucca Mountain site in terms of geology, hydrology, and climate. Information used to study possible mechanisms for the formation of the perched zone included data regarding isotopie and geochemical properties of the waters in and above the perched water zone; measured hydrologie parameters of the perched zone; geophysical and measured parameters of the tuff; megascopic and microscopic observations of the tuff, including mineralogical, alteration, and structural features; and the lateral and vertical extent of perched water in the region.

Aquifer test, geophysical, geochemical, and radioisotopic data show that fractures are the means by which water is recharging the perched zone. The reduced hydraulic conductivity of the formation in the perched zone appears to result from both a severe reduction in matrix porosity and permeability caused by welding, devitrification, and vapor phase crystallization; and by an increase in fracture filling which restricts the pathways for flow.

Nonlinear kink instabilities of high-Reynolds-number supersonic shear layers have been studied using high-resolution computer simulations with the piecewise-parabolic-method (PPM). The transition region between the two fluids of the shear layer is spread out over many computational zones to avoid numerical effects introduced on the smallest lengthscales. Mach number, density contrast, and perturbation speed and amplitude were varied to study their effects on the growth of the kink instabilities. In response to a perturbing sound wave, a travelling kink mode grows in amplitude until enough of a disturbance on the shear layer has been created for it to roll up and rapidly grow in thickness. The time it takes for this rapid growth to be initiated is proportional to the initial shear-layer thickness and increases for increasing Mach number or decreasing perturbation amplitude. For equal density, Mach 4 shear layers, perturbed by a sound wave with a 2% amplitude at the travelling mode velocity, the growth time is τg = (546 ± 24) δ/c, where c is the sound speed and δ the half-width of the shear layer.