Field experiments conducted at three locations in Georgia during 1991 and 1992 evaluated AC 263,222 and imazethapyr rates alone at 18, 36, 54, or 72 g ai/ha and in mixture for a total of 36, 54, or 72 g/ha of herbicide applied early-POST for weed control, peanut injury, and yield. An application of AC 263,222 at 72 g/ha controlled (> 90%) Ipomoea morningglories, sicklepod, smallflower morningglory, and yellow nutsedge in all experiments and coffee senna and Florida beggarweed at Chula in 1991. Bristly starbur was controlled at least 90% with AC 263,222 at 72 g/ha at Tifton in 1991, but less than 62% at Chula in 1991. Imazethapyr applied at 72 g/ha controlled coffee senna, Ipomoea morningglories, and smallflower morningglory at least 85%, but did not control Florida beggarweed or sicklepod and provided inconsistent bristly starbur and yellow nutsedge control. Bristly starbur and yellow nutsedge control was increased with several AC 263,222 plus imazethapyr mixtures. High peanut yields comparable to the standard were indicative of the AC 263,222 rate applied whether alone or in mixture with imazethapyr.