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Chapter 40 - Hematopoietic Cell Transplants for Waldenström Macroglobulinemia

from Section 12 - Hematopoietic Cell Transplants for Lymphomas: Changing Indications

Published online by Cambridge University Press:  24 May 2017

By
Veronika Bachanova ,
Robert Frank Cornell  and
Linda J. Burns
Edited by
Hillard M. Lazarus ,
Robert Peter Gale ,
Armand Keating ,
Andrea Bacigalupo ,
Reinhold Munker  and
Kerry Atkinson
Edited in association with
Syed Ali Abutalib
Hillard M. Lazarus
Affiliation:
Case Western Reserve University, Ohio
Robert Peter Gale
Affiliation:
Imperial College London
Armand Keating
Affiliation:
University of Toronto
Andrea Bacigalupo
Affiliation:
Ospedale San Martino, Genoa
Reinhold Munker
Affiliation:
Louisiana State University, Shreveport
Kerry Atkinson
Affiliation:
University of Queensland
Syed Ali Abutalib
Affiliation:
Midwestern Regional Medical Center, Cancer Treatment Centers of America, Chicago
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Type
Chapter
Information
Hematopoietic Cell Transplants
Concepts, Controversies and Future Directions
 , pp. 384 - 391
Publisher: Cambridge University Press
Print publication year: 2000

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References

Treon, SP, Patterson, CJ, Munshi, NC, Anderson, KC. Proceedings of the Seventh International Workshop on Waldenstrom Macroglobulinemia. Clin Lymphoma Myeloma Leuk 2013;13(2):181–183.CrossRefGoogle ScholarPubMed
Gertz, MA. Waldenstrom macroglobulinemia: 2013 update on diagnosis, risk stratification, and management. Am J Hematol 2013;88(8):703–711.CrossRefGoogle ScholarPubMed
Sahota, SS, Forconi, F, Ottensmeier, CH, Provan, D, Oscier, DG, Hamblin, TJ, et al. Typical Waldenstrom macroglobulinemia is derived from a B-cell arrested after cessation of somatic mutation but prior to isotype switch events. Blood 2002;100(4):1505–1507.CrossRefGoogle ScholarPubMed
Morton, LM, Wang, SS, Devesa, SS, Hartge, P, Weisenburger, DD, Linet, MS. Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001. Blood 2006 Jan 1;107(1):265-276.CrossRefGoogle ScholarPubMed
Boise, LH, Kaufman, JL, Heffner, LT, Shah, NN, Lechowicz, MJ, Lonial, S, et al. Changing epidemiology and improved survival in patients with Waldenstrom macroglobulinemia: review of surveillance, epidemiology, and end results (SEER) data. Blood 2013;122(21):3135–3135.Google Scholar
Castillo, JJ, Olszewski, AJ, Cronin, AM, Hunter, ZR, Treon, SP. Survival trends in Waldenstrom macroglobulinemia: an analysis of the Surveillance, Epidemiology and End Results database. Blood 2014;123(25):3999–4000.CrossRefGoogle ScholarPubMed
Ciccarelli, BT, Patterson, CJ, Hunter, ZR, Hanzis, C, Ioakimidis, L, Manning, R, et al. Hepcidin is produced by lymphoplasmacytic cells and is associated with anemia in Waldenstrom’s macroglobulinemia. Clin Lymphoma Myeloma Leuk 2011;11(1):160–163.CrossRefGoogle ScholarPubMed
Ansell, SM, Kyle, RA, Reeder, CB, Fonseca, R, Mikhael, JR, Morice, WG, et al. Diagnosis and management of Waldenstrom macroglobulinemia: Mayo stratification of macroglobulinemia and risk-adapted therapy (mSMART) guidelines. Mayo Clin Proc 2010;85(9):824–833.CrossRefGoogle ScholarPubMed
Garcia-Sanz, R, Montoto, S, Torrequebrada, A, de Coca, AG, Petit, J, Sureda, A, et al. Waldenstrom macroglobulinaemia: presenting features and outcome in a series with 217 cases. Br J Haematol 2001;115(3):575–582.CrossRefGoogle Scholar
Michael, AB, Lawes, M, Kamalarajan, M, Huissoon, A, Pratt, G. Cryoglobulinaemia as an acute presentation of Waldenstrom’s macroglobulinaemia. Br J Haematol 2004;124(5):565.CrossRefGoogle ScholarPubMed
Nobile-Orazio, E, Marmiroli, P, Baldini, L, Spagnol, G, Barbieri, S, Moggio, M, et al. Peripheral neuropathy in macroglobulinemia: incidence and antigen-specificity of M proteins. Neurology 1987;37(9):1506–1514.CrossRefGoogle ScholarPubMed
Mauro, FR, Foa, R, Cerretti, R, Giannarelli, D, Coluzzi, S, Mandelli, F, et al. Autoimmune hemolytic anemia in chronic lymphocytic leukemia: clinical, therapeutic, and prognostic features. Blood 2000;95(9):2786–2792.CrossRefGoogle ScholarPubMed
Treon, SP, Cao, Y, Xu, L, Yang, G, Liu, X, Hunter, ZR. Somatic mutations in MYD88 and CXCR4 are determinants of clinical presentation and overall survival in Waldenstrom macroglobulinemia. Blood 2014;123(18):2791–2796.CrossRefGoogle ScholarPubMed
Ocio, EM, Schop, RFJ, Gonzalez, B, Van Wier, SA, Hernandez-Rivas, JM, Gutierrez, NC, et al. 6q deletion in Waldenström macroglobulinemia is associated with features of adverse prognosis. Br J Haematol 2007;136(1):80–86.CrossRefGoogle ScholarPubMed
Nguyen-Khac, F, Lambert, J, Chapiro, E, Grelier, A, Mould, S, Barin, C, et al. Chromosomal aberrations and their prognostic value in a series of 174 untreated patients with Waldenström’s macroglobulinemia. Haematologica 2013;98(4):649–654.CrossRefGoogle Scholar
Sacco, A, Zhang, Y, Maiso, P, Manier, S, Rossi, G, Treon, SP, et al. microRNA aberrations in Waldenstrom macroglobulinemia. Clin Lymphoma Myeloma Leuk 2013;13(2):205–207.CrossRefGoogle ScholarPubMed
Roccaro, AM, Sacco, A, Jia, X, Azab, AK, Maiso, P, Ngo, HT, et al. microRNA-dependent modulation of histone acetylation in Waldenstrom macroglobulinemia. Blood 2010;116(9):1506–1514.CrossRefGoogle ScholarPubMed
Morel, P, Duhamel, A, Gobbi, P, Dimopoulos, MA, Dhodapkar, MV, McCoy, J, et al. International prognostic scoring system for Waldenström macroglobulinemia. Blood 2009;113(18):4163–4170.CrossRefGoogle ScholarPubMed
Kastritis, E, Zervas, K, Repoussis, P, Michali, E, Katodrytou, E, Zomas, A, et al. Prognostication in young and old patients with Waldenstrom’s macroglobulinemia: importance of the International Prognostic Scoring System and of serum lactate dehydrogenase. Clin Lymphoma Myeloma 2009;9(1):50–52.CrossRefGoogle Scholar
Kyle, RA, Treon, SP, Alexanian, R, Barlogie, B, Bjorkholm, M, Dhodapkar, M, et al. Prognostic markers and criteria to initiate therapy in Waldenstrom’s macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom’s Macroglobulinemia. Semin Oncol 2003;30(2):116–120.CrossRefGoogle ScholarPubMed
Dimopoulos, M, Kastritis, E, Owen, RG, Kyle, RA, Landgren, O, Morra, E, et al. Treatment recommendations for patients with Waldenström macroglobulinemia (WM) and related disorders: IWWM-7 consensus Blood 2014;124(9):1404–1411.CrossRefGoogle ScholarPubMed
Ricci, F, Tedeschi, A, Montillo, M, Morra, E. Therapy-related myeloid neoplasms in chronic lymphocytic leukemia and Waldenstrom’s macroglobulinemia. Mediterr J Hematol Infect Dis 2011;3(1):e2011031.CrossRefGoogle ScholarPubMed
Cornell, RF, Palmer, J. Adult acute leukemia. Dis Mon 2012;58(4):219–238.CrossRefGoogle ScholarPubMed
Leblond, V, Johnson, S, Chevret, S, Copplestone, A, Rule, S, Tournilhac, O, et al. Results of a randomized trial of chlorambucil versus fludarabine for patients with untreated Waldenström macroglobulinemia, marginal zone lymphoma, or lymphoplasmacytic lymphoma. J Clin Oncol 2013;31(3):301–307.CrossRefGoogle ScholarPubMed
Dimopoulos, MA, Alexanian, R, Gika, D, Anagnostopoulos, A, Zervas, C, Zomas, A, et al. Treatment of Waldenstrom’s macroglobulinemia with rituximab: prognostic factors for response and progression. Leuk Lymphoma 2004;45(10):2057–2061.CrossRefGoogle ScholarPubMed
Gertz, MA, Rue, M, Blood, E, Kaminer, LS, Vesole, DH, Greipp, PR. Multicenter phase 2 trial of rituximab for Waldenstrom macroglobulinemia (WM): an Eastern Cooperative Oncology Group Study (E3A98). Leuk Lymphoma 2004;45(10):2047–2055.CrossRefGoogle Scholar
Treon, SP, Emmanouilides, C, Kimby, E, Kelliher, A, Preffer, F, Branagan, AR, et al. Extended rituximab therapy in Waldenstrom’s macroglobulinemia. Ann Oncol 2005;16(1):132–138.CrossRefGoogle ScholarPubMed
Ghobrial, IM, Xie, W, Padmanabhan, S, Badros, A, Rourke, M, Leduc, R, et al. Phase II trial of weekly bortezomib in combination with rituximab in untreated patients with Waldenström Macroglobulinemia. Am J Hematol 2010;85(9):670–674.CrossRefGoogle ScholarPubMed
Dimopoulos, MA, Garcia-Sanz, R, Gavriatopoulou, M, Morel, P, Kyrtsonis, MC, Michalis, E, et al. Primary therapy of Waldenstrom macroglobulinemia (WM) with weekly bortezomib, low-dose dexamethasone, and rituximab (BDR): long-term results of a phase 2 study of the European Myeloma Network (EMN). Blood 2013;122(19):3276–3282.CrossRefGoogle ScholarPubMed
Treon, SP, Soumerai, JD, Branagan, AR, Hunter, ZR, Patterson, CJ, Ioakimidis, L, et al. Thalidomide and rituximab in Waldenstrom macroglobulinemia. Blood 2008;112(12):4452–4457.CrossRefGoogle ScholarPubMed
Treon, SP, Soumerai, JD, Branagan, AR, Hunter, ZR, Patterson, CJ, Ioakimidis, L, et al. Lenalidomide and rituximab in Waldenstrom’s macroglobulinemia. Clin Cancer Res 2009;15(1):355–360.CrossRefGoogle ScholarPubMed
Rosenthal, AC, Dueck, AC, Gano, K, Ansell, SM, Conley, C, Nowakowski, GS, et al. A Phase 2 Study of lenalidomide, rituximab, cyclophosphamide and dexamethasone (LR-CD) for untreated low grade non-Hodgkin lymphoma requiring therapy: Waldenström’s macroglobulinemia cohort results. Blood 2013;122(21):4352.Google Scholar
Chen, CI, Kouroukis, CT, White, D, Voralia, M, Stadtmauer, E, Stewart, AK, et al. Bortezomib is active in patients with untreated or relapsed Waldenstrom’s macroglobulinemia: a phase II study of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 2007;25(12):1570–1575.CrossRefGoogle ScholarPubMed
Treon, SP, Hanzis, C, Tripsas, C, Ioakimidis, L, Patterson, CJ, Manning, RJ, et al. Bendamustine therapy in patients with relapsed or refractory Waldenstrom’s macroglobulinemia. Clin Lymphoma Myeloma Leuk 2011;11(1):133–135.CrossRefGoogle ScholarPubMed
Ghobrial, IM, Witzig, TE, Gertz, M, LaPlant, B, Hayman, S, Camoriano, J, et al. Long-term results of the phase II trial of the oral mTOR inhibitor everolimus (RAD001) in relapsed or refractory Waldenstrom Macroglobulinemia. Am J Hematol 2014;89(3):237–242.CrossRefGoogle ScholarPubMed
Tripsas, CK, Yang, G, Cao, Y, Xu, L, Hunter, Z, Cropper, SJ, et al. A prospective multicenter study of the bruton’s tyrosine kinase inhibitor ibrutinib in patients with relapsed or refractory Waldenstrom’s macroglobulinemia. Blood 2013;122(21):251–251.Google Scholar
Anagnostopoulos, A, Dimopoulos, MA, Aleman, A, Weber, D, Alexanian, R, Champlin, R, et al. High-dose chemotherapy followed by stem cell transplantation in patients with resistant Waldenstrom’s macroglobulinemia. Bone Marrow Transplant 2001;27(10):1027–1029.CrossRefGoogle ScholarPubMed
Anagnostopoulos, A, Hari, PN, Pérez, WS, Ballen, K, Bashey, A, Bredeson, CN, et al. Autologous or Allogeneic Stem Cell Transplantation in Patients with Waldenstrom’s Macroglobulinemia. Biology of Blood and Marrow Transplantation 2006;12(8):845–854.CrossRefGoogle ScholarPubMed
Gilleece, MH, Pearce, R, Linch, DC, Wilson, M, Towlson, K, Mackinnon, S, et al. The outcome of haemopoietic stem cell transplantation in the treatment of lymphoplasmacytic lymphoma in the UK: a British Society Bone Marrow Transplantation study. Hematology 2008;13(2):119–127.CrossRefGoogle Scholar
Dhedin, N, Tabrizi, R, Bulabois, PE, Le Gouill, S, Coiteux, V, Dartigeas, C, et al. Hematopoietic stem cell transplantation (HSCT) in Waldenstrom macroglobulinemia (Wm): update of the French experience in 54 cases. ASH Annual Meeting Abstracts 2007;110(11):3015.Google Scholar
Kyriakou, C, Canals, C, Sibon, D, Cahn, JY, Kazmi, M, Arcese, W, et al. High-dose therapy and autologous stem-cell transplantation in Waldenström macroglobulinemia: The Lymphoma Working Party of the European Group for Blood and Marrow Transplantation. J Clin Oncol 2010;28(13):2227–2232.CrossRefGoogle ScholarPubMed
Dreger, P, Schmitz, N. Autologous stem cell transplantation as part of first-line treatment of Waldenstrom’s macroglobulinemia. Biol Blood Marrow Transplant 2007;13(5):623–624.CrossRefGoogle ScholarPubMed
Caravita, T, Siniscalchi, A, Tendas, A, Cupelli, L, Dentamaro, T, Natale, G, et al. High-dose therapy with autologous PBSC transplantation in the front-line treatment of Waldenstrom’s macroglobulinemia. Bone Marrow Transplant 2009;43(7):587–588.CrossRefGoogle ScholarPubMed
Munshi, NC, Barlogie, B. Role for high-dose therapy with autologous hematopoietic stem cell support in Waldenstrom’s macroglobulinemia. Semin Oncol 2003;30(2):282.CrossRefGoogle ScholarPubMed
Anagnostopoulos, A, Aleman, A, Giralt, S. Autologous and allogeneic stem cell transplantation in Waldenstrom’s macroglobulinemia: review of the literature and future directions. Semin Oncol 2003;30(2):286–290.CrossRefGoogle ScholarPubMed
Tournilhac, O, Leblond, V, Tabrizi, R, Gressin, R, Senecal, D, Milpied, N, et al. Transplantation in Waldenstrom’s macroglobulinemia: the French experience. Semin Oncol 2003;30(2):291–296.CrossRefGoogle ScholarPubMed
Stakiw, J, Kim, DH, Kuruvilla, J, Gupta, V, Messner, H, Lipton, JH. Evidence of graft-versus-Waldenstrom’s macroglobulinaemia effect after allogeneic stem cell transplantation: a single centre experience. Bone Marrow Transplant 2007;40(4):369–372.CrossRefGoogle ScholarPubMed
Meniane, JC, El-Cheikh, J, Faucher, C, Furst, S, Bouabdallah, R, Blaise, D, et al. Long-term graft-versus-Waldenstrom macroglobulinemia effect following reduced intensity conditioning allogeneic stem cell transplantation. Bone Marrow Transplant 2007;40(2):175–177.CrossRefGoogle ScholarPubMed
Maloney, D. Allogeneic transplantation following nonmyeloablative conditioning for aggressive lymphoma. Bone Marrow Transplant 2008;42(Suppl 1):S35–S36.CrossRefGoogle ScholarPubMed
Garnier, A, Robin, M, Larosa, F, Golmard, JL, Le Gouill, S, Coiteux, V, et al. Allogeneic hematopoietic stem cell transplantation allows long-term complete remission and curability in high-risk Waldenstrom’s macroglobulinemia. Results of a retrospective analysis of the Societe Francaise de Greffe de Moelle et de Therapie Cellulaire. Haematologica 2010;95(6):950–955.CrossRefGoogle ScholarPubMed
Owen, RG, Pratt, G, Auer, RL, Flatley, R, Kyriakou, C, Lunn, MP, et al. Guidelines on the diagnosis and management of Waldenstrom macroglobulinaemia. Br J Haematol 2014;165(3):316–333.CrossRefGoogle ScholarPubMed

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