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Chapter 11 - Management of Discordant Fetal Anomaly

Published online by Cambridge University Press:  11 October 2022

By
Rajit Narayan  and
Jon Hyett
Edited by
Leanne Bricker ,
Julian N. Robinson  and
Baskaran Thilaganathan
Leanne Bricker
Affiliation:
Corniche Hospital, Abu Dhabi
Julian N. Robinson
Affiliation:
Brigham & Women's Hospital, Boston
Baskaran Thilaganathan
Affiliation:
St George's Hospital Medical School, University of London
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Summary

Twin pregnancies may be complicated in a number of ways, including through presentation with fetal abnormality. Pregnancies that are discordant for fetal anomaly may be impacted by a range of complications which are dependent on zygosity, chorionicity and the specific anomaly concerned. Discordance is defined as “occurrence of a trait or disease in only one member of a matched pair of subjects, especially twins”. In this chapter, we have reviewed the prevalence of various fetal anomalies in twin pregnancies, identified means for detecting these prenatally and reviewed a range of approaches to managing these anomalies considering the impact on the affected fetus, the co-twin and the wider family.

Keywords

twin pregnancydiscordant anomalyselective reduction
Type
Chapter
Information
Management of Multiple Pregnancies
A Practical Guide
 , pp. 112 - 122
Publisher: Cambridge University Press
Print publication year: 2022

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