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Part 1 - Missing the Diagnosis Altogether

Published online by Cambridge University Press:  03 November 2020

Keith Josephs
Affiliation:
Mayo Clinic Alzheimer’s Disease Research Center
Federico Rodriguez-Porcel
Affiliation:
Medical University of South Carolina
Rhonna Shatz
Affiliation:
University of Cincinnati
Daniel Weintraub
Affiliation:
University of Pennsylvania
Alberto Espay
Affiliation:
University of Cincinnati
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Publisher: Cambridge University Press
Print publication year: 2020

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References

References

Harada, C. N., Natelson Love, M. C. and Triebel, K. L. 2013. Normal cognitive aging. Clin Geriatr Med 29(4) 737752.CrossRefGoogle ScholarPubMed
Howieson, D. B. et al. 1993. Neurologic function in the optimally healthy oldest old: neuropsychological evaluation. Neurology 43(10) 18821886.CrossRefGoogle ScholarPubMed
Park, D. C. and Reuter-Lorenz, P. 2009. The adaptive brain: aging and neurocognitive scaffolding. Annu Rev Psychol 60 173196.CrossRefGoogle ScholarPubMed
Salthouse, T. A. 2010. Selective review of cognitive aging. J Int Neuropsychol Soc 16(5) 754760.CrossRefGoogle ScholarPubMed
Stevens, W. D., Hasher, L., Chiew, K. S. and Grady, C. L. 2008. A neural mechanism underlying memory failure in older adults. J Neurosci 28(48) 1282012824.CrossRefGoogle ScholarPubMed
Treitz, F. H., Heyder, K. and Daum, I. 2007. Differential course of executive control changes during normal aging. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 14(4) 370393.CrossRefGoogle ScholarPubMed

References

Aarsland, D. et al. 2010. Mild cognitive impairment in Parkinson disease: a multicenter pooled analysis. Neurology 75(12) 10621069.CrossRefGoogle ScholarPubMed
Aarsland, D., Taylor, J. P. and Weintraub, D. 2014. Psychiatric issues in cognitive impairment. Mov Disord 29(5) 651662.CrossRefGoogle ScholarPubMed
Duncan, G. W. et al. 2014. Health-related quality of life in early Parkinson’s disease: the impact of nonmotor symptoms. Mov Disord 29(2) 195202.Google Scholar
Global Parkinson’s Disease Survey Steering Committee. 2002. Factors Impacting on Quality of Life in Parkinson’s Disease: Results From an International Survey. Mov Disord 17(1) 6067.CrossRefGoogle Scholar
Monastero, R. et al. 2013. The neuropsychiatric profile of Parkinson’s disease subjects with and without mild cognitive impairment. J Neural Transm (Vienna) 120(4) 607611.CrossRefGoogle ScholarPubMed
Potter, G. G. and Steffens, D. C. 2007. Contribution of depression to cognitive impairment and dementia in older adults. Neurologist 13(3) 105117.CrossRefGoogle ScholarPubMed
Reijnders, J. S. et al. 2008. A systematic review of prevalence studies of depression in Parkinson’s disease. Mov Disord 23(2) 183189; quiz 313.CrossRefGoogle ScholarPubMed
Schulz, P. E. and Arora, G. 2015. Depression. Continuum 21(3) 756771.Google Scholar
Shulman, L. M., Taback, R. L., Rabinstein, A. A. and Weiner, W. J. 2002. Non-recognition of depression and other non-motor symptoms in Parkinson’s disease. Parkinsonism Relat Disord 8(3) 193197.CrossRefGoogle ScholarPubMed
Timmer, M. H. M., van Beek, M., Bloem, B. R. and Esselink, R. A. J. 2017. What a neurologist should know about depression in Parkinson’s disease. Pract Neurol 17(5) 359368.CrossRefGoogle ScholarPubMed
Weintraub, D. et al. 2004. Effect of psychiatric and other nonmotor symptoms on disability in Parkinson’s disease. J Am Geriatr Soc 52(5) 784788.Google Scholar

References

Campbell, J. and Sharma, A. 2013. Compensatory changes in cortical resource allocation in adults with hearing loss. Front Syst Neurosci 7 71.CrossRefGoogle ScholarPubMed
Deal, J. A. et al. 2017. Hearing impairment and incident dementia and cognitive decline in older adults: the health ABC study. J Gerontol A Biol Sci Med Sci 72(5) 703709.Google Scholar
Fletcher, P. D. et al. 2015. Auditory hedonic phenotypes in dementia: a behavioural and neuroanatomical analysis. Cortex 67 95105.Google Scholar
Golden, E. C. and Josephs, K. A. 2015. Minds on replay: musical hallucinations and their relationship to neurological disease. Brain 138(Pt 12) 37933802.CrossRefGoogle ScholarPubMed
Hardy, C. J. et al. 2016. Hearing and dementia. J Neurol 263(11) 23392354.Google Scholar
Jayakody, D. M. P., Friedland, P. L., Martins, R. N. and Sohrabi, H. R. 2018. Impact of aging on the auditory system and related cognitive functions: a narrative review. Front Neurosci 12 125.CrossRefGoogle ScholarPubMed
Lin, F. R. et al. 2011. Hearing loss and cognition in the Baltimore Longitudinal Study of Aging. Neuropsychology 25(6) 763770.CrossRefGoogle ScholarPubMed
Wingfield, A. et al. 2006. Effects of adult aging and hearing loss on comprehension of rapid speech varying in syntactic complexity. J Am Acad Audiol 17(7) 487497.Google ScholarPubMed

References

Alexander, G. E., DeLong, M. R. and Strick, P. L. 1986. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 9 357381.CrossRefGoogle ScholarPubMed
Bettcher, B. M. et al. 2016. Neuroanatomical substrates of executive functions: beyond prefrontal structures. Neuropsychologia 85 100109.Google Scholar
Cummings, J. L. 1997. The Neuropsychiatric Inventory: assessing psychopathology in dementia patients. Neurology 48(5 Suppl 6) S1016.CrossRefGoogle ScholarPubMed
Duff, K. 2010. Predicting premorbid memory functioning in older adults. Appl Neuropsychol 17(4) 278282.CrossRefGoogle ScholarPubMed
Gregory, C. A., Serra-Mestres, J. and Hodges, J. R. 1999. Early diagnosis of the frontal variant of frontotemporal dementia: how sensitive are standard neuroimaging and neuropsychologic tests? Neuropsychiatry Neuropsychol Behav Neurol 12(2) 128135.Google ScholarPubMed
Kertesz, A., Davidson, W. and Fox, H. 1997. Frontal behavioral inventory: diagnostic criteria for frontal lobe dementia. Can J Neurol Sci 24(1) 2936.CrossRefGoogle ScholarPubMed
Krueger, C. E. et al. 2011. Double dissociation in the anatomy of socioemotional disinhibition and executive functioning in dementia. Neuropsychology 25(2) 249259.Google Scholar
Marin, R. S., Biedrzycki, R. C. and Firinciogullari, S. 1991. Reliability and validity of the Apathy Evaluation Scale. Psychiatry Res 38(2) 143162.CrossRefGoogle ScholarPubMed
Mesulam, M. M. 1998. From sensation to cognition. Brain 121(6) 10131052.CrossRefGoogle ScholarPubMed
Rascovsky, K. et al. 2011. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain 134(Pt 9) 24562477.Google Scholar

References

Alexopoulos, G. S. et al. 2002. Clinical presentation of the “depression-executive dysfunction syndrome” of late life. Am J Geriatr Psychiatry 10(1) 98106.Google ScholarPubMed
Ballard, C. G. et al. 2004. Neuropathological substrates of psychiatric symptoms in prospectively studied patients with autopsy-confirmed dementia with Lewy bodies. Am J Psychiatry 161(5) 843849.CrossRefGoogle ScholarPubMed
Black, W. and Almeida, O. P. 2004. A systematic review of the association between the behavioral and psychological symptoms of dementia and burden of care. Int Psychogeriatr 16(3) 295315.CrossRefGoogle ScholarPubMed
Chakrabarty, T., Sepehry, A. A., Jacova, C. and Hsiung, G. Y. 2015. The prevalence of depressive symptoms in frontotemporal dementia: a meta-analysis. Dement Geriatr Cogn Disord 39(5–6) 257271.CrossRefGoogle ScholarPubMed
Cummings, J. et al. 2016. Role of donepezil in the management of neuropsychiatric symptoms in Alzheimer’s disease and dementia with Lewy bodies. CNS Neurosci Ther 22(3) 159166.CrossRefGoogle ScholarPubMed
Dudas, R., Malouf, R., McCleery, J. and Dening, T. 2018. Antidepressants for treating depression in dementia. Cochrane Database Syst Rev 8 Cd003944.Google ScholarPubMed
Feldman, H. et al. 2004. Behavioral symptoms in mild cognitive impairment. Neurology 62(7) 11991201.CrossRefGoogle ScholarPubMed
Ford, A. H. 2014. Neuropsychiatric aspects of dementia. Maturitas 79(2) 209215.CrossRefGoogle ScholarPubMed
Goldman, J. G. and Postuma, R. 2014. Premotor and nonmotor features of Parkinson’s disease. Curr Opin Neurol 27(4) 434441.CrossRefGoogle ScholarPubMed
Ismail, Z. et al. 2016. Neuropsychiatric symptoms as early manifestations of emergent dementia: provisional diagnostic criteria for mild behavioral impairment. Alzheimers Dement 12(2) 195202.CrossRefGoogle ScholarPubMed
Ismail, Z. et al. 2017. The Mild Behavioral Impairment Checklist (MBI-C): a rating scale for neuropsychiatric symptoms in pre-dementia populations. J Alzheimers Dis 56(3) 929938.CrossRefGoogle ScholarPubMed
Ismail, Z. et al. 2018. Affective and emotional dysregulation as pre-dementia risk markers: exploring the mild behavioral impairment symptoms of depression, anxiety, irritability, and euphoria. Int Psychogeriatr 30(2) 185196.Google Scholar
McShane, R., Areosa Sastre, A. and Minakaran, N. 2006. Memantine for dementia. Cochrane Database Syst Rev 2 Cd003154.Google Scholar
Orgeta, V., Qazi, A., Spector, A. E. and Orrell, M. 2014. Psychological treatments for depression and anxiety in dementia and mild cognitive impairment. Cochrane Database Syst Rev 1 Cd009125.Google Scholar
Rapp, M. A. et al. 2011. Cognitive decline in patients with dementia as a function of depression. Am J Geriatr Psychiatry 19(4) 357363.CrossRefGoogle ScholarPubMed
Rush, A. J. et al. 2006. Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression. N Engl J Med 354(12) 12311242.CrossRefGoogle ScholarPubMed
Starkstein, S. E. et al. 2011. Diagnostic criteria for depression in Alzheimer disease: a study of symptom patterns using latent class analysis. Am J Geriatr Psychiatry 19(6) 551558.CrossRefGoogle ScholarPubMed
Taragano, F. E. et al. 2009. Mild behavioral impairment and risk of dementia: a prospective cohort study of 358 patients. J Clin Psychiatry 70(4) 584592.CrossRefGoogle ScholarPubMed

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