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Chapter 3 - Meiosis: How to Get a Good Start in Life

Published online by Cambridge University Press:  15 December 2022

By
Ursula Eichenlaub-Ritter
Edited by
Stéphane Viville  and
Karen D. Sermon
Stéphane Viville
Affiliation:
Laboratoire de Génétique Médicale de Strasbourg and Laboratoire de diagnostic génétique, Strasbourg
Karen D. Sermon
Affiliation:
Reproduction and Genetics Research Group, Vrije Universiteit Brussel
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Summary

Meiosis comprises fundamental processes that permit sexual reproduction and species evolution. In addition to producing haploid gametes, it provides for a stochastic distribution of maternally and paternally inherited chromosomes, which undergo allelic recombination thereby increasing genetic variability in the next generation. Thus it provides for diversity within a population, and is essential for the formation of euploid germ cells that will contribute to a euploid healthy embryo after fertilization. Meiosis is therefore the basis for maintaining genomic integrity, high developmental potential, and health of the embryo and offspring, and normal fertility in males and females [1,2]. Furthermore, it is the basis of changes in the genome that are important for adaptation and evolution of species.

Type
Chapter
Information
Textbook of Human Reproductive Genetics , pp. 31 - 47
Publisher: Cambridge University Press
Print publication year: 2023

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