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Chapter 9 - Mood Disorders in Parkinson’s Disease

Published online by Cambridge University Press:  05 March 2022

By
Po-Heng Tsai  and
Ganesh Gopalakrishna
Edited by
Néstor Gálvez-Jiménez ,
Amos D. Korczyn  and
Ramón Lugo-Sanchez
Néstor Gálvez-Jiménez
Affiliation:
Florida International University
Amos D. Korczyn
Affiliation:
Tel-Aviv University
Ramón Lugo-Sanchez
Affiliation:
Cleveland Clinic
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Summary

Parkinson’s disease (PD) is traditionally characterized by its motor symptoms of tremors, bradykinesia, rigidity, and postural instability [1]. However, it is now recognized that non-motor symptoms including neuropsychiatric manifestations are frequently present in PD, and their onset not only could precede motor symptoms but is also associated with increased dysfunction and reduced quality of life [2–4]. This chapter focuses on depression, the most commonly seen mood disorder in PD, and provides an overview of the epidemiology, clinical symptoms, proposed pathophysiology, diagnostic tools, and treatment options available for depression in PD.

Type
Chapter
Information
Non-motor Parkinson's Disease , pp. 91 - 98
Publisher: Cambridge University Press
Print publication year: 2022

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