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Chapter 14 - Sexual Dysfunction in Parkinson’s Disease

Published online by Cambridge University Press:  05 March 2022

Néstor Gálvez-Jiménez
Affiliation:
Florida International University
Amos D. Korczyn
Affiliation:
Tel-Aviv University
Ramón Lugo-Sanchez
Affiliation:
Cleveland Clinic
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Summary

Parkinson’s disease (PD) is an age-related neurodegenerative multisystem progressive disorder belonging to the α-synucleinopathy spectrum, with well-known and widely reported motor symptoms, such as tremor, rigidity, bradykinesia, and postural instability, and with highly prevalent and previously often neglected non-motor symptoms (NMS) [1], such as pain, depression, anxiety, sleep disturbances, cognitive dysfunction, and many others, that may precede the motor symptoms [2]. Sexual dysfunction (SD) is usually included in the category of autonomic NMS in PD, even though its etiology is multifactorial and involves interaction with other motor and NMS of PD [3–5]. Patients with PD rated SD twelfth out of 24 most bothersome symptoms of their disease [6], but SD remains an underrated non-motor feature of PD despite its high frequency and severe impact on the patient’s quality of life [7, 8].

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Publisher: Cambridge University Press
Print publication year: 2022

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