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  • Print publication year: 2019
  • Online publication date: October 2019

Chapter 1 - Pathophysiology of Epilepsy

Summary

A seizure is a situational clinical event that may be instigated by any number of extrinsic or intrinsic precipitating factors and that results in an excessive, hypersynchronous discharge of a cortical neuronoglial population and manifests in the brain in either a localized or widespread manner. This abnormal activity takes over the normal functioning of one or more brain networks to result in seizures that characterize over 40 recognized epileptic syndromes.1

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