Inherited Thrombophilia and Venous Thromboembolism in Pregnancy

Amira El-Messidi; Audrey-Ann Labrecque

doi:10.1017/9781108975780.062

Chapter 52 - Inherited Thrombophilia and Venous Thromboembolism in Pregnancy

from Section 9 - Hematologic Conditions in Pregnancy

Published online by Cambridge University Press: 23 February 2023

Amira El-Messidi and

Audrey-Ann Labrecque

Edited by

Amira El-Messidi and

Alan D. Cameron

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Amira El-Messidi: Affiliation:
McGill University, Montréal
Alan D. Cameron: Affiliation:
University of Glasgow

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Summary

A 28-year-old nulligravida with known factor V Leiden mutation is referred by her primary care provider to your hospital center’s high-risk obstetrics unit for preconception counseling.

Keywords

Inherited thrombophilia, pregnancy Deep venous thrombosis (DVT)Pulmonary embolism Physiology Risk factors Physical examination Virchow’s triad Anticoagulant pathway Preconception counseling Investigations, serum, imaging, compression ultrasound, magnetic resonance imaging, chest X-ray, lung scintigraphy, ventilation/perfusion scan, computed tomographic pulmonary imaging Perinatal risks, complications, maternal-fetal morbidity, adverse outcome Antepartum, intrapartum, postpartum management Heparin, anticoagulation, low molecular weight, unfractionated heparin Protamine sulfate, reversal of anticoagulation Contraception

Type: Chapter
Information: OSCEs in Obstetrics and Maternal-Fetal Medicine
An Evidence-Based Approach
, pp. 662 - 679

DOI: https://doi.org/10.1017/9781108975780.062 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2023

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References

Suggested Readings

American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins–Obstetrics. ACOG Practice Bulletin No. 197: Inherited thrombophilias in pregnancy. Obstet Gynecol. 2018;132(1):e18–e34. [Correction in Obstet Gynecol. 2018 Oct;132(4):1069]CrossRef Google Scholar

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