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Chapter 6 - Resting-State Functional Connectivity in Unipolar Depression

from Section 3 - Functional and Neurochemical Brain Studies

Published online by Cambridge University Press:  12 January 2021

By
Ziqi Chen  and
Qiyong Gong
Edited by
Sudhakar Selvaraj ,
Paolo Brambilla  and
Jair C. Soares
Sudhakar Selvaraj
Affiliation:
UTHealth School of Medicine, USA
Paolo Brambilla
Affiliation:
Università degli Studi di Milano
Jair C. Soares
Affiliation:
UT Harris County Psychiatric Center, USA
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Summary

Unipolar depression, also known as unipolar or major depressive disorder (MDD), is a globally prevalent psychiatric disorder characterized by persistent sadness and a loss of interest in normally enjoyable activities, accompanied by an inability to carry out daily activities, for at least two weeks. Furthermore, patients with unipolar depression usually exhibit some of the following symptoms: loss of energy, sleeping more or less, anxiety, change in appetite, reduced concentration, indecisiveness, feeling of worthlessness, guilt, hopelessness, and thoughts or acts of self-harm or suicide. The lifetime risk of depression is approximately 10–20%, with rates being almost doubled in women.

Type
Chapter
Information
Mood Disorders
Brain Imaging and Therapeutic Implications
 , pp. 49 - 58
Publisher: Cambridge University Press
Print publication year: 2021

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