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2.45 - Clomipramine

from Tricyclic Antidepressants

Published online by Cambridge University Press:  19 October 2021

Michael Cummings
Affiliation:
University of California, Los Angeles
Stephen Stahl
Affiliation:
University of California, San Diego
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Summary

Typical or first-generation antipsychotic (FGA)

Type
Chapter
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Publisher: Cambridge University Press
Print publication year: 2021

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References

Kelly, M. W., Myers, C. W. (1990). Clomipramine: a tricyclic antidepressant effective in obsessive compulsive disorder. Ann Pharmacother, 24, 739744.Google Scholar
Gex-Fabry, M., Balant-Gorgia, A. E., Balant, L. P. (1999). Clomipramine concentration as a predictor of delayed response: a naturalistic study. Eur J Clin Pharmacol, 54, 895902.CrossRefGoogle ScholarPubMed
Charlier, C., Pinto, E., Ansseau, M., et al. (2000). Relationship between clinical effects, serum drug concentration, and concurrent drug interactions in depressed patients treated with citalopram, fluoxetine, clomipramine, paroxetine or venlafaxine. Hum Psychopharmacol, 15, 453459.3.0.CO;2-F>CrossRefGoogle ScholarPubMed
Herrera, D., Mayet, L., Galindo, M. C., et al. (2000). Pharmacokinetics of a sustained-release dosage form of clomipramine. J Clin Pharmacol, 40, 14881493.CrossRefGoogle ScholarPubMed
Hicks, J. K., Sangkuhl, K., Swen, J. J., et al. (2017). Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update. Clin Pharmacol Ther, 102, 3744.CrossRefGoogle ScholarPubMed
Evans, L. E., Bett, J. H., Cox, J. R., et al. (1980). The bioavailability of oral and parenteral chlorimipramine (Anafranil). Prog Neuropsychopharmacol, 4, 293302.CrossRefGoogle ScholarPubMed
Balant-Gorgia, A. E., Gex-Fabry, M., Balant, L. P. (1991). Clinical pharmacokinetics of clomipramine. Clin Pharmacokinet, 20, 447462.CrossRefGoogle ScholarPubMed
Vandel, S., Bertschy, G., Baumann, P., et al. (1995). Fluvoxamine and fluoxetine: interaction studies with amitriptyline, clomipramine and neuroleptics in phenotyped patients. Pharmacol Res, 31, 347353.CrossRefGoogle ScholarPubMed
Rasmussen, B. B., Nielsen, T. L., Brøsen, K. (1998). Fluvoxamine inhibits the CYP2C19-catalysed metabolism of proguanil in vitro. Eur J Clin Pharmacol, 54, 735740. doi: 710.1007/s002280050544CrossRefGoogle ScholarPubMed
Pigott, T. A., Seay, S. M. (1999). A review of the efficacy of selective serotonin reuptake inhibitors in obsessive-compulsive disorder. J Clin Psychiatry, 60, 101106. doi: 110.4088/jcp.v4060n0206CrossRefGoogle ScholarPubMed
Albert, U., Aguglia, E., Maina, G., et al. (2002). Venlafaxine versus clomipramine in the treatment of obsessive-compulsive disorder: a preliminary single-blind, 12-week, controlled study. J Clin Psychiatry, 63, 10041009. doi: 1010.4088/jcp.v1063n1108CrossRefGoogle ScholarPubMed
Undurraga, J., Baldessarini, R. J. (2017). Direct comparison of tricyclic and serotonin-reuptake inhibitor antidepressants in randomized head-to-head trials in acute major depression: systematic review and meta-analysis. J Psychopharmacol, 31, 11841189.CrossRefGoogle ScholarPubMed

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  • Clomipramine
  • Edited by Michael Cummings, University of California, Los Angeles, Stephen Stahl, University of California, San Diego
  • Book: Management of Complex Treatment-resistant Psychotic Disorders
  • Online publication: 19 October 2021
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  • Clomipramine
  • Edited by Michael Cummings, University of California, Los Angeles, Stephen Stahl, University of California, San Diego
  • Book: Management of Complex Treatment-resistant Psychotic Disorders
  • Online publication: 19 October 2021
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Clomipramine
  • Edited by Michael Cummings, University of California, Los Angeles, Stephen Stahl, University of California, San Diego
  • Book: Management of Complex Treatment-resistant Psychotic Disorders
  • Online publication: 19 October 2021
Available formats
×