Book contents
- Fetal Therapy
- Fetal Therapy
- Copyright page
- Dedication
- Contents
- Contributors
- Foreword
- Section 1: General Principles
- Chapter 1 The Rationale for Fetal Therapy
- Chapter 2 A Fetal Origin of Adult Disease
- Chapter 3 Human Embryology: Molecular Mechanisms of Embryonic Disease
- Chapter 4 Human Genetics and Fetal Disease: Assessment of the Fetal Genome
- Chapter 5 Interventions in Pregnancy to Reduce Risk of Stillbirth
- Chapter 6 Fetal Therapy Choices: Uncertain and Emotional Decisions and the Doctor’s Role in Parental Decision-Making
- Chapter 7 The Ethics of Consent for Fetal Therapy
- Chapter 8 Open Fetal Surgery: Is There Still a Role?
- Chapter 9 The Artificial Womb
- Section 2: Fetal Disease: Pathogenesis and Treatment
- Section III: The Future
- Index
- References
Chapter 1 - The Rationale for Fetal Therapy
from Section 1: - General Principles
Published online by Cambridge University Press: 21 October 2019
Book contents
- Fetal Therapy
- Fetal Therapy
- Copyright page
- Dedication
- Contents
- Contributors
- Foreword
- Section 1: General Principles
- Chapter 1 The Rationale for Fetal Therapy
- Chapter 2 A Fetal Origin of Adult Disease
- Chapter 3 Human Embryology: Molecular Mechanisms of Embryonic Disease
- Chapter 4 Human Genetics and Fetal Disease: Assessment of the Fetal Genome
- Chapter 5 Interventions in Pregnancy to Reduce Risk of Stillbirth
- Chapter 6 Fetal Therapy Choices: Uncertain and Emotional Decisions and the Doctor’s Role in Parental Decision-Making
- Chapter 7 The Ethics of Consent for Fetal Therapy
- Chapter 8 Open Fetal Surgery: Is There Still a Role?
- Chapter 9 The Artificial Womb
- Section 2: Fetal Disease: Pathogenesis and Treatment
- Section III: The Future
- Index
- References
Summary
In 1982, a group of subspecialists in fetal medicine, pediatric surgery, pediatrics, radiology, genetics, and bioethics reported on a meeting that discussed the emerging field of ‘fetal therapy’ [1]. Their summary statement laid down the foundation and principles for the treatment of prenatally diagnosed congenital anomalies where the natural history of the disease can potentially be influenced by intervention before birth (Table 1.1). In principle, this document defines the criteria of candidate conditions for fetal therapy, the goals of fetal treatment, and the appropriate setting for where fetal therapy should be performed. Since this original publication there have been significant advances in prenatal diagnostic and prognostic assessments of the fetus, the scope of treatments, and the care settings where fetal therapy is offered that require consideration [2].
- Type
- Chapter
- Information
- Fetal TherapyScientific Basis and Critical Appraisal of Clinical Benefits, pp. 1 - 7Publisher: Cambridge University PressPrint publication year: 2020
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