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VIII.89 - Meningitis

from Part VIII - Major Human Diseases Past and Present

Published online by Cambridge University Press:  28 March 2008

Kenneth F. Kiple
Affiliation:
Bowling Green State University, Ohio
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Summary

Meningitis is an acute inflammation of the meninges, the membranes covering the brain and spinal cord. The disease is usually the result of bacterial infection, but a number of viruses, fungi, and other microbial agents can also cause it. Meningitis can develop as well from noninfectious conditions such as tumors, lead poisoning, and reactions to vaccines. Meningococcal meningitis, caused by a bacterium, Neisseria meningitidis, is the only form that occurs in major epidemics. Also called cerebrospinal meningitis (CSM), it has been known in the past as “spotted fever,” cerebrospinal fever, typhus cerebralis, and meningitis epidemica. Aseptic meningitis refers to inflammations of the meninges without detectable bacterial involvement. The most common causes are any of a number of viruses.

Etiology and Epidemiology

Many species of bacteria can cause meningitis, but over 80 percent of all cases in developed countries in recent years have been due to only three: N. meningitidis, Hemophilus influenzae, and Streptococcus (Diplococcus) pneumoniae. Other common members of the human bacterial flora such as Escherichia coli and various streptococci and staphylococci can also produce meningitis under special circumstances, as can members of the genera Listeria, Pseudomonas, and Proteus. Meningitis sometimes develops as a complication of tuberculosis.

Aseptic meningitis is usually the result of viral infection. Among the many types of viruses that can be involved are mumps, echovirus, poliovirus, coxsackievirus, herpes simplex, herpes zoster, hepatitis, measles, rubella, and several mosquito-borne agents of encephalitis. Fungi, most commonly Cryptococcus, are other possible agents.

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Chapter
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Publisher: Cambridge University Press
Print publication year: 1993

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References

,Centers for Disease Control. 1986. Summary of notifiable diseases, United States, 1986. Atlanta.
Danielson, L., and Mann, E.. 1983. The first American account of cerebrospinal meningitis. Reviews of Infectious Diseases 5:. [Reprint of 1806 article].CrossRefGoogle ScholarPubMed
Dowling, Harry F. 1977. Fighting infection: Conquests of the twentieth century. Cambridge, Mass..CrossRefGoogle Scholar
Hirsch, August. 1886. Handbook of geographical and historical pathology, Vol. III. London.Google Scholar
Lapeyssonie, L. 1963. La Méningite cérébro-spinale en Afrique. Bulletin of The World Health Organization 28 (Supplement).Google Scholar
Netter, Arnold, and Debré, Robert. 1911. La Méningite cérébrospinale. Paris.Google Scholar
Patterson, K. David, and Hartwig, Gerald W.. 1984. Cerebrospinal meningitis in West Africa and Sudan in the twentieth century. Los Angeles.Google Scholar
Solente, Lucy. 1938. Histoire de l évolution des méningites cérébro-spinales aiguës. Révue de Médicine 55.Google Scholar
Vedros, Neylan A., ed. 1987. Evolution of meningococcal disease, 2 vols. Boca Raton, Fla..Google Scholar
Waddy, B. B. 1957. African epidemic cerebro-spinal meningitis. Journal of Tropical Medicine and Hygiene 60.Google Scholar

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  • Meningitis
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.151
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  • Meningitis
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.151
Available formats
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Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Meningitis
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.151
Available formats
×