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5 - Nanoscale optical microscopy

Published online by Cambridge University Press:  05 November 2012

Lukas Novotny  and
Bert Hecht
Lukas Novotny
Affiliation:
University of Rochester, New York and ETH Zürich, Switzerland
Bert Hecht
Affiliation:
Julius-Maximilians-Universität Würzburg, Germany
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Summary

Optical measurement techniques, and near-field optical microscopy in particular, exist in a broad variety of configurations. In the following we will derive an interaction series to understand and categorize different experimental configurations. The interaction series describes multiple scattering events between an optical probe and a sample and is similar to the Born series in light scattering. We will start out by discussing far-field microscopy first and then proceed with selected configurations encountered in near-field optical microscopy.

The interaction series

The interaction of light with matter can be discussed in terms of light scattering events [1, 2]. Figure 5.1 is a sketch of a generic geometry considered in the following. The sample and – in the case of near-field optical microscopy – also an optical probe, which is positioned in close proximity, are assumed to be described by dielectric susceptibilities η(r) and χ(r), respectively. An incident light field Ei is illuminating the probe-sample region. Ei is assumed to be a solution of the homogeneous Helmholtz equation (2.35). The incoming field causes a scattered wave Es, which is detectable in the far-field. The total field is then given by E = Ei + Es. In a qualitative picture, there are several processes that can convert an incoming photon into a scattered photon. For example, the incoming photon may be scattered only at the probe or only at the sample before traveling into the far-field.

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Principles of Nano-Optics , pp. 131 - 164
Publisher: Cambridge University Press
Print publication year: 2012

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References

[1] J., Sun, P. S., Carney, and J. C., Schotland “Strong tip effects in near-field scanning optical tomography,” J. Appl. Phys. 102, 103103 (2007).Google Scholar
[2] M., Born and E., Wolf, Principles of Optics, 7th edn. New York: Cambridge University Press (1999).Google Scholar
[3] S.W., Hell, M., Schrader, P. E., Hänninen, and E., Soini, “Resolving fluorescence beads at 100–200 nm axial distance with a two photon 4π-microscope operated in the near infrared,” Opt. Commun. 120, 129–133 (1995).Google Scholar
[4] R. H., Webb, “Confocal optical microscopy,” Rep. Prog. Phys. 59, 427–471 (1996).Google Scholar
[5] J. B., Pawley (ed.), Handbook of Biological Confocal Microscopy, 2nd edn. New York: Plenum Press (1995).
[6] S. W., Hell and E. H. K., Stelzer, “Properties of a 4π-confocal fluorescence microscope,” J. Opt. Soc. Am.A 9, 2159–2166 (1992).Google Scholar
[7] S., Lindek, R., Pick, and E. H. K., Stelzer, “Confocal theta microscope with three objective lenses,” Rev. Sci. Instrum. 65, 3367–3372 (1994).Google Scholar
[8] S.W., Hell, Increasing the Resolution of Far-Field FluorescenceMicroscopy by Point-Spread-Function Engineering. New York: Plenum Press (1997).Google Scholar
[9] M., Göppert-Mayer, “Über die Wahrscheinlichkeit des Zusammenwirkens zweier Lichtquanten in einem Elementarakt,” Naturwissenschaften 17, 932 (1929).Google Scholar
[10] W., Kaiser and C. G. B., Garret, “Two-photon excitation in CaF2:Eu2+,” Phys. Rev. Lett. 7, 229–231 (1961).Google Scholar
[11] W., Denk, J. H., Strickler, and W. W., Webb, “2-Photon laser scanning fluorescence microscopy,” Science 248, 73–76 (1990).Google Scholar
[12] P. S., Dittrich and P., Schwille, “Photobleaching and stabilization of fluorophores used for single-molecule analysis with one- and two-photon excitation,” Appl. Phys.B 73, 829–837 (2001).Google Scholar
[13] S. W., Hell, “Towards fluorescence nanoscopy,” Nature Biotechnol. 21, 1347–1355 (2003).Google Scholar
[14] P. D., Maker and R. W., Terhune, “Study of optical effects due to an induced polarization third order in the electric field strength,” Phys. Rev.A 137, 801–818 (1965).Google Scholar
[15] A., Zumbusch, G. R., Holtom, and X. S., Xie, “Three-dimensional vibrational imaging by coherent anti-Stokes Raman scattering,” Phys. Rev. Lett. 82, 4142–4145 (1999).Google Scholar
[16] C.W., Freudiger, W., Min, B. G., Saar et al., “Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy,” Science 322, 1857–1861 (2008).Google Scholar
[17] S.M., Mansfield and G. S., Kino, “Solid immersion microscope,” Appl. Phys. Lett. 77, 2615–2616 (1990).Google Scholar
[18] B. D., Terris, H. J., Mamin, and D., Rugar, “Near-field optical data storage,” Appl. Phys. Lett. 68, 141–143 (1996).Google Scholar
[19] S. B., Ippolito, B. B., Goldberg, and M. S., Ünlü, “High spatial resolution subsurface microscopy,” Appl. Phys. Lett. 78, 4071–4073 (2001).Google Scholar
[20] B. B., Goldberg, S. B., Ippolito, L., Novotny, Z., Liu, and M. S., Ünlü, “Immersion lens microscopy of nanostructures and quantum dots,” IEEE J. Selected Topics Quantum Electron. 8, 1051–1059 (2002).Google Scholar
[21] L. P., Ghislain and V. B., Elings, “Near-field scanning solid immersion microscope,” Appl. Phys. Lett. 72, 2779–2781 (1998).Google Scholar
[22] L.P., Ghislain, V.B., Elings, K.B., Crozier, et al., “Near-field photolithography with a solid immersion lens,” Appl. Phys. Lett. 74, 501–503 (1999).Google Scholar
[23] T. D., Milster, F., Akhavan, M., Bailey, et al., “Super-resolution by combination of a solid immersion lens and an aperture,” Jap. J. Appl. Phys. 40, 1778–1782 (2001).Google Scholar
[24] J. N., Farahani, H. J., Eisler, D. W., Pohl, and B., Hecht, “Single quantum dot coupled to a scanning optical antenna: a tunable super emitter,” Phys. Rev. Lett. 95, 017402 (2005).Google Scholar
[25] S. T., Hess, T. P. K., Girirajan, and M. D., Mason “Ultra-high resolution imaging by fluorescence photoactivation localization microscopy,” Biophys. J. 91, 4258–4272 (2006).Google Scholar
[26] T. J., Gould and S. T., Hess “Nanoscale biological fluorescence imaging: breaking the diffraction barrier,” Methods Cell Bio. 89, 329–358 (2008). With permission from Elsevier.Google Scholar
[27] M. J., Rust, M., Bates, and X., Zhuang, “Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM),” Nature Methods 3, 793–795 (2006).Google Scholar
[28] E., Betzig, G. H., Patterson, R., Sougrat, et al., “Imaging intracellular fluorescent proteins at nanometer resolution,” Science 313, 1642–1645 (2006).Google Scholar
[29] M., Hofmann, C., Eggeling, S., Jakobs, and S. W., Hell, “Breaking the diffraction barrier in fluorescence microscopy at low light intensities by using reversibly photoswitchable proteins,” Proc. Nat. Acad. Sci. 102, 17565–17569 (2005).Google Scholar
[30] M. F., Juette, T. J., Gould, M. D., Lessard, et al., “Three-dimensional sub-100 nm resolution fluorescence microscopy of thick samples,” Nature Methods 5, 527–529 (2008).Google Scholar
[31] B., Huang, W., Wang, M., Bates, and X., Zhuang, “Three-dimensional super-resolution imaging by stochastic optical reconstruction microscopy,” Science 319, 810–813 (2008).Google Scholar
[32] B., Hecht, H., Bielefeldt, D. W., Pohl, L., Novotny, and H., Heinzelmann, “Influence of detection conditions on near-field optical imaging,” J. Appl. Phys. 84, 5873–5882 (1998).Google Scholar
[33] D., Courjon, K., Sarayeddine, and M., Spajer, “Scanning tunneling optical microscopy,” Opt. Commun. 71, 23–28 (1989).Google Scholar
[34] R. C., Reddick, R. J., Warmack, D.W., Chilcott, S. L., Sharp, and T. L., Ferrell, “Photon scanning tunneling microscopy,” Rev. Sci. Instrum. 61, 3669–3677 (1990).Google Scholar
[35] M. L. M., Balistreri, J. P., Korterik, L., Kuipers, and N. F., van Hulst, “Phase mapping of optical fields in integrated optical waveguide structures,” J. Lightwave Technol. 19, 1169–1176 (2001).Google Scholar
[36] M. L. M., Balistreri, H., Gersen, J. P., Korterik, L., Kuipers, and N. F., van Hulst, “Tracking femtosecond laser pulses in space and time,” Science 294, 1080–1082 (2001).Google Scholar
[37] R. J., Engelen, Y., Sugimoto, H., Gersen, et al., “Ultrafast evolution of photonic eigenstates in k-space,” Nature Phys. 3, 401–405 (2007). Reprinted by permission from Macmillan Publisher Ltd.Google Scholar
[38] R., Esteban, R., Vogelgesang, J., Dorfmüller, et al., “Direct near-field optical imaging of higher order plasmonic resonances,” Nano Lett. 8, 3155–3159 (2008).Google Scholar
[39] C., Hoeppener and L., Novotny “Antenna-based optical imaging of single Ca2+ transmembrane proteins in liquids,” Nano Lett. 8, 642–646 (2008). Copyright 2008 American Chemical Society.Google Scholar
[40] M. R., Beversluis, A., Bouhelier, and L., Novotny, “Continuum generation from single gold nanostructures through near-field mediated intraband transitions,” Phys. Rev.B 68, 115433 (2003).Google Scholar
[41] A., Bouhelier, M., Beversluis, A., Hartschuh, and L., Novotny, “Near-field second-harmonic generation induced by local field enhancement,” Phys. Rev. Lett. 90, 013903 (2003).Google Scholar
[42] H. G., Frey, F., Keilmann, A., Kriele, and R., Guckenberger, “Enhancing the resolution of scanning near-field optical microscopy by a metal tip grown on an aperture probe,” Appl. Phys. Lett. 81, 5030–5032 (2002).Google Scholar
[43] R. M., Stockle, Y. D., Suh, V., Deckert, and R., Zenobi, “Nanoscale chemical analysis by tip-enhanced Raman spectroscopy,” Chem. Phys. Lett. 318, 131–136 (2000).Google Scholar
[44] T., Ichimura, N., Hayazawa, M., Hashimoto, Y., Inouye, and S., Kawata, “Tip-enhanced coherent anti-Stokes Raman scattering for vibrational nanoimaging,” Phys. Rev. Lett. 92, 220801 (2004).Google Scholar
[45] H., Metiu, “Surface enhanced spectroscopy,” Prog. Surf. Sci. 17, 153–320 (1984).Google Scholar
[46] L. G., Cancado, A., Jorio, A., Hartschuh, et al., “Mechanism of near-field Raman enhancement in one-dimensional systems,” Phys. Rev. Lett. 103, 186101 (2009). Copyright 2009 American Physical Society.Google Scholar
[47] F., Keilmann and R., Hillenbrand, “Near-field microscopy by elastic light scattering from a tip,” Phil. Trans. Roy. Soc. Lond.A 362, 787–805 (2004).Google Scholar
[48] T. J., Yang, G. A., Lessard, and S. R., Quake, “An apertureless near-field microscope for fluorescence imaging,” Appl. Phys. Lett. 76, 378–380 (2000).Google Scholar
[49] C., Xie, C., Mu, J. R., Cox, and J. M., Gerton “Tip-enhanced fluorescence microscopy of high-density samples,” Appl. Phys. Lett. 89, 143117 (2006).Google Scholar
[50] C., Hoeppener, R., Beams and L., Novotny “Background suppression in near-field optical imaging,” Nano Lett. 9, 903–908 (2009).Google Scholar
[51] Ch., Adelmann, J., Hetzler, G., Scheiber, et al., “Experiments on the depolarization near-field scanning optical microscope,” Appl. Phys. Lett. 74, 179–181 (1999).Google Scholar
[52] N., Hosaka and T., Saiki, “Near-field fluorescence imaging of single molecules with a resolution in the range of 10 nm,” J. Microsc. 202, 362–364 (2001).Google Scholar
[53] U. Ch., Fischer, U. T., Dürig, and D.W., Pohl, “Near-field optical scanning microscopy in reflection,” Appl. Phys. Lett. 52, 249–251 (1988).Google Scholar

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