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Chapter 7 - Sperm Vitality: Hypo-Osmotic Swelling Test

Published online by Cambridge University Press:  05 April 2021

Ashok Agarwal
The Cleveland Clinic Foundation, Cleveland, OH
Ralf Henkel
University of the Western Cape, South Africa
Ahmad Majzoub
Hamad Medical Corporation, Doha
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The hypo-osmotic swelling (HOS) test, introduced in 1987 to assess the functional integrity of the human sperm membrane, appears to have withstood the test of time. Many articles have been published on the subject since its inclusion in the third edition of the World Health Organization (WHO) manual in 1992 [1, 2, 3, 4, 5].

Publisher: Cambridge University Press
Print publication year: 2021

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