Celestial navigation is an important means of maritime navigation; it can automatically achieve inertially referenced positioning and orientation after a long period of development. However, the impact of different accuracy of observations and the influence of nonstationary states, such as ship speed change and steering, are not taken into account in existing algorithms. To solve this problem, this paper proposes an adaptively robust maritime celestial navigation algorithm, in which each observation value is given an equivalent weight according to the robust estimation theory, and the dynamic balance between astronomical observation and prediction values of vessel motion is adjusted by applying the adaptive factor. With this system, compared with the frequently used least square method and extended Kalman filter algorithm, not only are the real-time and high-precision navigation parameters, such as position, course, and speed for the vessel, calculated simultaneously, but also the influence of abnormal observation and vessel motion status change could be well suppressed.

Recent regional cooling has impacted the natural systems of the Antarctic Peninsula (AP); however, little is known concerning the changes in the high parts of the glacial systems. Dry-snow line (DSL), situated in the high parts of glaciers, is the uppermost limit of frequent or occasional surface melt. We analyse dry-snow line altitude (DSLA) changes on the AP during 2004–2020 using C-band synthetic aperture radar time series data. We demonstrate that the DSLA in the eastern part of the AP is usually higher than that of the western part. Moreover, using simulated climatic variables from regional climate models, the lowering in altitude of DSL of glaciers in most areas is identified as a response to a decrease in snowmelt and an increase in precipitation. Furthermore, correlation analyses between simulated climatic variables and the DSLA are conducted. These results present the sensitive response of variations in DSLA to meteorological conditions, and the capability of DSLA being a proxy of polar local climate in high-altitude areas with no in situ meteorological observations.

The FNDC5 gene encodes the fibronectin type III domain-containing protein 5 that is a membrane protein mainly expressed in skeletal muscle, and the FNDC5 rs3480 polymorphism may be associated with liver disease severity in non-alcoholic fatty liver disease (NAFLD). We investigated the influence of the FNDC5 rs3480 polymorphism on the relationship between sarcopenia and the histological severity of NAFLD. A total of 370 adult individuals with biopsy-proven NAFLD were studied. The association between the key exposure sarcopenia and the outcome liver histological severity was investigated by binary logistic regression. Stratified analyses were undertaken to examine the impact of FNDC5 rs3480 polymorphism on the association between sarcopenia and the severity of NAFLD histology. Patients with sarcopenia had more severe histological grades of steatosis and a higher prevalence of significant fibrosis and definite non-alcoholic steatohepatitis than those without sarcopenia. There was a significant association between sarcopenia and significant fibrosis (adjusted OR 2·79, 95 % CI 1·31, 5·95, P = 0·008), independent of established risk factors and potential confounders. Among patients with sarcopenia, significant fibrosis occurred more frequently in the rs3480 AA genotype carriers than in those carrying the FNDC5 rs3480 G genotype (43·8 v. 17·2 %, P = 0·031). In the association between sarcopenia and liver fibrosis, there was a significant interaction between the FNDC5 genotype and sarcopenia status (P value for interaction = 0·006). Sarcopenia is independently associated with significant liver fibrosis, and the FNDC5 rs3480 G variant influences the association between sarcopenia and liver fibrosis in patients with biopsy-proven NAFLD.

The effects of carbon equivalent on thermal and mechanical properties of compacted graphite cast irons were investigated at ambient temperature, 300 and 500 °C, respectively. The group implied the change of carbon content to control the carbon equivalent. The results indicated that with the increasing carbon equivalent from 4.43 to 4.74, the graphite count increase. The thermal conductivity was 48.64, 44.55, 49.04, and 50.36 W/mK for carbon equivalent about 4.43–4.74 of compacted graphite cast irons at ambient temperature, respectively. With an increase in temperature, the thermal conductivity decrease. Moreover, with the increasing carbon equivalent, the tensile strength and yield strength increase initially, and then decrease at ambient temperature, 300 and 500 °C, respectively. With an increase in temperature, the tensile strength and yield strength decrease. Characterization of fracture surface indicated that the mixed ductile-brittle fracture mode prevailed in the compacted graphite cast irons with different carbon equivalents.

Considerable controversy exists regarding the associations of dietary patterns with the risk of all-cause, CVD and stroke mortality. Therefore, a meta-analysis was conducted to elucidate the potential associations between dietary patterns and the risk of all-cause, CVD and stroke mortality. The PubMed database was searched for prospective cohort studies on the associations between dietary patterns and the risk of all-cause, CVD and stroke mortality published until February 2014. Random-effects models were used to calculate the summary relative risk estimates (SRRE) based on the highest v. the lowest category of dietary pattern scores. Stratified analyses were conducted based on sex, geographical region, follow-up duration, and adjustment/non-adjustment for energy intake. A total of thirteen prospective cohort studies involving 338 787 participants were included in the meta-analysis. There was evidence of inverse associations between the prudent/healthy dietary pattern and the risk of all-cause (SRRE = 0·76, 95 % CI 0·68, 0·86) and CVD (SRRE = 0·81, 95 % CI 0·75, 0·87) mortality and an absence of association between this dietary pattern and stroke mortality (SRRE = 0·89, 95 % CI 0·77, 1·02). However, no significant associations were observed between the Western/unhealthy dietary pattern and the risk of all-cause (SRRE = 1·07, 95 % CI 0·96, 1·20), CVD (SRRE = 0·99, 95 % CI 0·91, 1·08) and stroke (SRRE = 0·94, 95 % CI 0·81, 1·10) mortality. In conclusion, the findings provide evidence that greater adherence to a prudent/healthy dietary pattern is associated with a lower risk of all-cause and CVD mortality and not significantly associated with stroke mortality and that the Western/unhealthy dietary pattern is not associated with all-cause, CVD and stroke mortality. Further studies are required to confirm these findings.

Celestial navigation is an important type of autonomous navigation technology which could be used as an alternative to Global Navigation Satellite Systems (GNSS) when a vessel is at sea. After several centuries of development, a variety of astronomical vessel position (AVP) determination methods have been invented, but the basic concepts of these methods are all based on angular observations with a device such as a sextant, which has disadvantages including low accuracy, manual operation, and a limited period of observation. This paper proposes a new method that utilises a fisheye camera to image the celestial bodies and horizon simultaneously. Then, we calculate the obliquity of the fisheye camera's principal optical axis according to the image coordinates of the horizon. Next, we calculate the altitude of the celestial bodies according to the image coordinates of the celestial bodies and the obliquity. Finally, the AVP is determined by the altitudes according to the robust estimation method. Experimental results indicate that this method not only could realize automation and miniaturization of the AVP determination system, but could also greatly improve the efficiency of celestial navigation.

A useful procedure is described to rapidly obtain Bragg-reflection intensities from the FULLPROF suite, and the Bragg intensities can then be input into the GEST and the PECKCRYST programs for crystal-structure determination of small molecules. An example on using the new procedure for the structure determination from powder diffraction determination of hydrochlorothiazide (C7H8ClN3O4S2) is presented, and the powder-structure results obtained by the PECKCRYST program are in good agreement with previously reported single-crystal results.

A traditional assumption is that schistosome cercariae lose their tails at the onset of penetration. It has, however, recently been demonstrated that, for Schistosoma mansoni, cercarial tails were not invariably being shed as penetration took place and a high proportion of tails entered human skin under experimental conditions. This phenomenon was termed delayed tail loss (DTL). In this paper, we report that DTL also happens with S. japonicum cercariae during penetration of mouse skin. It occurred at all cercarial densities tested, from as few as 10 cercariae/2·25 cm2 of mouse skin up to 200 cercariae. Furthermore, it was demonstrated that there was a density-dependent increase in DTL as cercarial densities increased. No such density-dependent enhancement was shown for percentage attachment over the same cercarial density range.

An ecofriendly process has been successfully developed to synthesize the polycrystalline silver nanopolyhedrons with a high yield at large scale. By using tannic acid in the presence of poly (vinyl pyrrolidone) (PVP), high quality silver nanopolyhedrons were obtained in an aqueous one-pot reaction without any templates or auxiliaries. The film made from the silver nanostructures exhibits an electrical conductivity higher than 104 S/cm on both rigid and flexible substrates. The supreme mechanical strength of this silver film recommends its wide application in printing and flexible electronics.