We have demonstrated strong multimode photonic microresonator and nanoparticle interactions by using an integrated micro disk resonator from through port of the laser coupling bus waveguide. In addition to the fundamental resonance mode, disk resonator has higher order resonance modes. The excited higher order mode has a node at the position where the electromagnetic energy of the fundamental mode is close to a maximum. Here we report that a self referencing mechanism can be achieved by simultaneous excitation of both fundamental and 2nd order micro disk optical resonance modes. Additionally, we are able to measure the area around the maximum of the fundamental resonance mode and the node of the higher order mode, which have overlaps in the disk. In this work, we used on chip disk microresonator as the example, as a variety of types of optical microresonators have been investigated; we used nanoparticle to interact with the two optical resonance modes excited by the coupling bus waveguide, where the nanoparticle can be either dielectric materials or metallic materials. The strong photonic microresonator and nanoparticle interactions have variety of applications for optical switches, waveguides and detection. The self-referencing characteristics of the two optical resonance modes have potential to achieve photonic functions independent of external perturbation, such as temperature change.