To send content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about sending content to .
To send content items to your Kindle, first ensure firstname.lastname@example.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Functional plasticity in CNS system
Kurt Haas, Department of Cellular and Physiological Sciences, Brain Research Centre, University of British Columbia, Vancouver, BC, Canada,
Hollis T. Cline, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA
This chapter discusses current knowledge of how precisely ordered afferent synaptogenesis occurs during development. It also explains the potential for reforming functional circuits by correct rewiring during regeneration. Most of the knowledge of the mechanisms involved in establishing circuits between distant central nervous system (CNS) neuronal populations comes from studies of the axonal projection from the eye to central brain targets. The output neurons of the eye are the retinal ganglion cells (RGCs), whose axons exit the eye as the optic nerve, cross the midline at the optic chiasm, and innervate central brain structures. RGCs in fish and frogs survive optic nerve lesion and sprout new axonal extensions that correctly navigate to the tectum, reform the retinotectal map, and demonstrate visual responsivity. Regeneration recapitulates a critical period of heightened plasticity during which activity-dependent mechanisms mediate map refinement through pruning of ectopic axonal branches.
Email your librarian or administrator to recommend adding this to your organisation's collection.