1. The interrelationship between cholesterol and vitamin A metabolism has been studied in rats.
2. The effect of cholesterol feeding in increasing the liver storage of cholesterol w-as enhanced during vitamin A deficiency.
3. This effect was due to an increased rate of absorption of cholesterol and not due to a decreased turnover rate.
4. Feeding of high levels of vitamin A markedly depressed the cholesterol absorption; however, its turnover was unaffected.