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Natural disasters are increasing in frequency and impact; they cause widespread disruption and adversity throughout the world. The Canterbury earthquakes of 2010–2011 were devastating for the people of Christchurch, New Zealand. It is important to understand the impact of this disaster on the mental health of children and adolescents.
To report psychiatric medication use for children and adolescents following the Canterbury earthquakes.
Dispensing data from community pharmacies for the medication classes antidepressants, antipsychotics, anxiolytics, sedatives/hypnotics and methylphenidate are routinely recorded in a national database. Longitudinal data are available for residents of the Canterbury District Health Board (DHB) and nationally. We compared dispensing data for children and adolescents residing in Canterbury DHB with national dispensing data to assess the impact of the Canterbury earthquakes on psychotropic prescribing for children and adolescents.
After longer-term trends and population adjustments are considered, a subtle adverse effect of the Canterbury earthquakes on dispensing of antidepressants was detected. However, the Canterbury earthquakes were not associated with higher dispensing rates for antipsychotics, anxiolytics, sedatives/hypnotics or methylphenidate.
Mental disorders or psychological distress of a sufficient severity to result in treatment of children and adolescents with psychiatric medication were not substantially affected by the Canterbury earthquakes.
A new optical delivery system has been developed for the (scanning) transmission electron microscope. Here we describe the in situ and “rapid ex situ” photothermal heating modality of the system, which delivers >200 mW of optical power from a fiber-coupled laser diode to a 3.7 μm radius spot on the sample. Selected thermal pathways can be accessed via judicious choices of the laser power, pulse width, number of pulses, and radial position. The long optical working distance mitigates any charging artifacts and tremendous thermal stability is observed in both pulsed and continuous wave conditions, notably, no drift correction is applied in any experiment. To demonstrate the optical delivery system’s capability, we explore the recrystallization, grain growth, phase separation, and solid state dewetting of a Ag0.5Ni0.5 film. Finally, we demonstrate that the structural and chemical aspects of the resulting dewetted films was assessed.
This paper explores how the Generalized Continuum Hypothesis (GCH) arose from Cantor's Continuum Hypothesis in the work of Peirce, Jourdain, Hausdorff, Tarski, and how GCH was used up to Gödel's relative consistency result.
The Val158Met polymorphism of the catechol-O-methyltransferase (COMT) gene may be related to individual differences in cognition, likely via modulation of prefrontal dopamine catabolism. However, the available studies have yielded mixed results, possibly in part because they do not consistently account for other genes that affect cognition. We hypothesized that COMT Met allele homozygosity, which is associated with higher levels of prefrontal dopamine, would predict better executive function as measured using standard neuropsychological testing, and that other candidate genes might interact with COMT to modulate this effect. Participants were 95 healthy, right-handed adults who underwent genotyping and cognitive testing. COMT genotype predicted executive ability as measured by the Trail-Making Test, even after covarying for demographics and Apolipoprotein E (APOE), brain-derived neurotrophic factor (BDNF), and ankyrin repeat and kinase domain containing 1 (ANKK1) genotype. There was a COMT-ANKK1 interaction in which individuals having both the COMT Val allele and the ANKK1 T allele showed the poorest performance. This study suggests the heterogeneity in COMT effects reported in the literature may be due in part to gene–gene interactions that influence central dopaminergic systems. (JINS, 2011, 17, 1–7)
This is the first translation of Fichte's addresses to the German nation for almost 100 years. The series of 14 speeches, delivered whilst Berlin was under French occupation after Prussia's disastrous defeat at the Battle of Jena in 1806, is widely regarded as a founding document of German nationalism, celebrated and reviled in equal measure. Fichte's account of the distinctiveness of the German people and his belief in the native superiority of its culture helped to shape German national identity throughout the nineteenth century and beyond. With an extensive introduction that puts Fichte's argument in its intellectual and historical context, this edition brings an important and seminal work to a modern readership. All of the usual series features are provided, including notes for further reading, chronology, and brief biographies of key individuals.
We mentioned at the end of our previous address that there are in circulation among us still more false ideas and delusive theories concerning the affairs of peoples, and that these prevent the Germans from coming to a definite view of their present situation that would be appropriate to their particular character. These phantoms are at this very time being offered around for public veneration with even greater zeal and, since so much else has begun to totter and become uncertain, they might be considered by some solely as a way of filling the vacuum that has arisen; therefore, it seems pertinent to the matter in hand to submit these to a more serious examination than their importance would otherwise merit.
To begin with, and above all else, the first, original and truly natural frontiers of states are undoubtedly their inner frontiers. Those who speak the same language are already, before all human art, joined together by mere nature with a multitude of invisible ties; they understand one another and are able to communicate ever more clearly; they belong together and are naturally one, an indivisible whole. No other nation of a different descent and language can desire to absorb and assimilate such a people without, at least temporarily, becoming confused and profoundly disturbing the steady progress of its own culture. The external limits of territories only follow as a consequence of this inner frontier, drawn by man's spiritual nature itself.
The following addresses were delivered as a series of lectures in Berlin during the winter of 1807–8 and are a continuation of my Characteristics of the Present Age, which I presented during the winter of 1804–5 in the same location (and which were printed by this publisher in 1806). What had to be said to the public in and through them is expressed clearly enough in the work itself, and it therefore had no need of a foreword. Since, however, in the meantime a number of blank pages have resulted by the manner in which these addresses were put together, I have filled this space with material that has in part already been passed by the censor and published elsewhere. Of this material I was reminded by the circumstances that led to these blank pages arising in the first place, for it would seem to have general application in this instance also. I refer the reader in particular to the conclusion of the Twelfth Address, which touches on this same subject.
From a Treatise on Machiavelli as writer, with extracts from his works
From the conclusion of that treatise
We can think of two species of men against whom we should like to safeguard ourselves if we could. First, those who assume, just because they are unable in their thoughts to get beyond what is printed in the latest newspaper, that no one else can either; that accordingly everything which is said or written has some relation to this newspaper and should serve as a commentary thereon.
In the last address we examined what the principal differences would be between a people that continued to develop in its original language and one that adopted a foreign language. We said on that occasion: as far as foreigners are concerned, we wished to leave it to each observer's judgement to decide whether those phenomena really occurred which, according to our assertions, were bound to occur; but as far as the Germans are concerned, we pledged to demonstrate that they really revealed themselves as, according to our assertions, the people with an original language was bound to reveal itself. Today we shall make good our promise and set forth the proof for our claims by examining, first of all, the last great and, in a certain sense, completed world deed [Welt-That] of the German people, the Reformation of the Church.
Christianity, which originated in Asia and by its corruption became more Asiatic than ever, preaching dumb submission and blind faith, was something strange and exotic even to the Romans. They never truly penetrated and appropriated it, and divided its essence into two incongruous halves; whereupon the attachment of the foreign part was accomplished with the aid of the melancholy superstition they had inherited from their ancestors. Among the immigrated Teutons this religion acquired adherents who had no prior intellectual training [Verstandesbildung] to hinder its acceptance, but also no hereditary superstition favourable to it.