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The majority of psychological treatment research is dedicated to investigating the effectiveness of cognitive behavioural therapy (CBT) across different conditions, population and contexts. We aimed to summarise the current systematic review evidence and evaluate the consistency of CBT's effect across different conditions. We included reviews of CBT randomised controlled trials in any: population, condition, format, context, with any type of comparator and published in English. We searched DARE, Cochrane, MEDLINE, EMBASE, PsycINFO, CINAHL, CDAS, and OpenGrey between 1992 and January 2019. Reviews were quality assessed, their data extracted and summarised. The effects upon health-related quality of life (HRQoL) were pooled, within-condition groups. If the across-condition heterogeneity was I2 < 75%, we pooled effects using a random-effect panoramic meta-analysis. We summarised 494 reviews (221 128 participants), representing 14/20 physical and 13/20 mental conditions (World Health Organisation's International Classification of Diseases). Most reviews were lower-quality (351/494), investigated face-to-face CBT (397/494), and in adults (378/494). Few reviews included trials conducted in Asia, South America or Africa (45/494). CBT produced a modest benefit across-conditions on HRQoL (standardised mean difference 0.23; 95% confidence intervals 0.14–0.33, I2 = 32%). The effect's associated prediction interval −0.05 to 0.50 suggested CBT will remain effective in conditions for which we do not currently have available evidence. While there remain some gaps in the completeness of the evidence base, we need to recognise the consistent evidence for the general benefit which CBT offers.
Gravitational waves from coalescing neutron stars encode information about nuclear matter at extreme densities, inaccessible by laboratory experiments. The late inspiral is influenced by the presence of tides, which depend on the neutron star equation of state. Neutron star mergers are expected to often produce rapidly rotating remnant neutron stars that emit gravitational waves. These will provide clues to the extremely hot post-merger environment. This signature of nuclear matter in gravitational waves contains most information in the 2–4 kHz frequency band, which is outside of the most sensitive band of current detectors. We present the design concept and science case for a Neutron Star Extreme Matter Observatory (NEMO): a gravitational-wave interferometer optimised to study nuclear physics with merging neutron stars. The concept uses high-circulating laser power, quantum squeezing, and a detector topology specifically designed to achieve the high-frequency sensitivity necessary to probe nuclear matter using gravitational waves. Above 1 kHz, the proposed strain sensitivity is comparable to full third-generation detectors at a fraction of the cost. Such sensitivity changes expected event rates for detection of post-merger remnants from approximately one per few decades with two A+ detectors to a few per year and potentially allow for the first gravitational-wave observations of supernovae, isolated neutron stars, and other exotica.
We sample certain results from the theory of q-series, including summation and transformation formulas, as well as some recent results which are not available in book form. Our approach is systematic and uses the Askey–Wilson calculus and Rodrigues-type formulas.
The purpose of this chapter is to give an elementary introduction to the most fundamental aspects of elliptic hypergeometric functions. We will also give some indication of their historical origin in statistical mechanics. We will explain how elliptic hypergeometric functions can be used to construct biorthogonal rational functions, generalizing the famous Askey scheme of orthogonal polynomials. Apart from some general mathematical maturity, the only prerequisites will be elementary linear algebra and complex function theory.
The aim of this chapter is to introduce the formal theory of general orthogonal polynomials and present the two dual combinatorial approaches due to Foata for the special function aspects of the orthogonal polynomials, and to Flajolet and Viennot for the lattice paths models used for the moments and general orthogonal polynomials. After reviewing the standard interplay between orthogonal polynomials and combinatorics, influenced by their pioneering works, we will report on some recent topics developed in this cross-cutting field of these two branches of mathematics.
Many special functions are eigenfunctions to explicit operators, such as difference and differential operators, which is in particular true for the special functions occurring in the Askey scheme, its q-analogue and extensions. The study of the spectral properties of such operators leads to explicit information for the corresponding special functions. We discuss several instances of this application, involving orthogonal polynomials and their matrix-valued analogues.
We consider two important extensions of the classical and classical discrete orthogonal polynomials: namely, Krall and exceptional polynomials. We also explore the relationship between both extensions and how they can be used to expand the Askey tableau.
In ‘Inviting a Friend to Supper’ Jonson celebrates an Horatian ideal of modest conviviality with intimates. The ironies of that poem, which hint at excesses waiting to erupt, point to another way in which he could be seen – as a man given to bodily excess and driven by his appetites. The anecdote of Jonson drawn drunk through Paris on a cart by his young tutee, Wat Raleigh, helped construct that image, along with the many references to his love of wine and to his physically imposing body. This essay explores the ways in which Jonson’s London plays – especially Epicene, Bartholomew Fair, and The Alchemist – contributed to his popular image as a recorder of and participant in the sensory excesses possible in the urban context where he spent much of his life. Jonson was acutely attuned to the sensory environment of London: to the sounds, sights, smells, and touches that invited its residents to indulge their senses even while threatening to shatter their self-control and social identities. This essay demonstrates the role of the urban plays in the construction of a Jonson whose contemporary image was in part defined by his corporeality and immersion in the life of the senses.
Written by experts in their respective fields, this collection of pedagogic surveys provides detailed insight and background into five separate areas at the forefront of modern research in orthogonal polynomials and special functions at a level suited to graduate students. A broad range of topics are introduced including exceptional orthogonal polynomials, q-series, applications of spectral theory to special functions, elliptic hypergeometric functions, and combinatorics of orthogonal polynomials. Exercises, examples and some open problems are provided. The volume is derived from lectures presented at the OPSF-S6 Summer School at the University of Maryland, and has been carefully edited to provide a coherent and consistent entry point for graduate students and newcomers.
The SPARC tokamak is a critical next step towards commercial fusion energy. SPARC is designed as a high-field ($B_0 = 12.2$ T), compact ($R_0 = 1.85$ m, $a = 0.57$ m), superconducting, D-T tokamak with the goal of producing fusion gain $Q>2$ from a magnetically confined fusion plasma for the first time. Currently under design, SPARC will continue the high-field path of the Alcator series of tokamaks, utilizing new magnets based on rare earth barium copper oxide high-temperature superconductors to achieve high performance in a compact device. The goal of $Q>2$ is achievable with conservative physics assumptions ($H_{98,y2} = 0.7$) and, with the nominal assumption of $H_{98,y2} = 1$, SPARC is projected to attain $Q \approx 11$ and $P_{\textrm {fusion}} \approx 140$ MW. SPARC will therefore constitute a unique platform for burning plasma physics research with high density ($\langle n_{e} \rangle \approx 3 \times 10^{20}\ \textrm {m}^{-3}$), high temperature ($\langle T_e \rangle \approx 7$ keV) and high power density ($P_{\textrm {fusion}}/V_{\textrm {plasma}} \approx 7\ \textrm {MW}\,\textrm {m}^{-3}$) relevant to fusion power plants. SPARC's place in the path to commercial fusion energy, its parameters and the current status of SPARC design work are presented. This work also describes the basis for global performance projections and summarizes some of the physics analysis that is presented in greater detail in the companion articles of this collection.
The current study aims to describe the Mediterranean diet (MD) adherence across the US regions, and explore the predictive factors of MD adherence among US adults.
Design:
Cross-sectional secondary data analysis. MD adherence score (0–9) was calculated using the Block 98 FFQ. Hot spot analysis was conducted to describe the geospatial distribution of MD adherence across the US regions. Logistic regression explored predictors of MD adherence.
Setting:
Nationwide community-dwelling residency in the USA.
Participants:
Adults aged ≥45 years (n 20 897) who participated in the REasons for Geographic and Racial Differences in Stroke study and completed baseline assessment during January 2003 and October 2007.
Results:
The mean of MD adherence score was 4·36 (sd 1·70), and 46·5 % of the sample had high MD adherence (score 5–9). Higher MD adherence clusters were primarily located in the western and northeastern coastal areas of the USA, whereas lower MD adherence clusters were majorly observed in south and east-north-central regions. Being older, black, not a current smoker, having a college degree or above, an annual household income ≥ $US 75K, exercising ≥4 times/week and watching TV/video <4 h/d were each associated with higher odds of high MD adherence.
Conclusions:
There were significant geospatial and population disparities in MD adherence across the US regions. Future studies are needed to explore the causes of MD adherence disparities and develop effective interventions for MD promotion in the USA.
Many studies demonstrate that marriage protects against risky alcohol use and moderates genetic influences on alcohol outcomes; however, previous work has not considered these effects from a developmental perspective or in high-risk individuals. These represent important gaps, as it cannot be assumed that marriage has uniform effects across development or in high-risk samples. We took a longitudinal developmental approach to examine whether marital status was associated with heavy episodic drinking (HED), and whether marital status moderated polygenic influences on HED. Our sample included 937 individuals (53.25% female) from the Collaborative Study on the Genetics of Alcoholism who reported their HED and marital status biennially between the ages of 21 and 25. Polygenic risk scores (PRS) were derived from a genome-wide association study of alcohol consumption. Marital status was not associated with HED; however, we observed pathogenic gene-by-environment effects that changed across young adulthood. Among those who married young (age 21), individuals with higher PRS reported more HED; however, these effects decayed over time. The same pattern was found in supplementary analyses using parental history of alcohol use disorder as the index of genetic liability. Our findings indicate that early marriage may exacerbate risk for those with higher polygenic load.
The default mode network (DMN) dysfunction has emerged as a consistent biological correlate of multiple psychiatric disorders. Specifically, there is evidence of alterations in DMN cohesiveness in schizophrenia, mood and anxiety disorders. The aim of this study was to synthesize at a fine spatial resolution the intra-network functional connectivity of the DMN in adults diagnosed with schizophrenia, mood and anxiety disorders, capitalizing on powerful meta-analytic tools provided by activation likelihood estimation.
Methods.
Results from 70 whole-brain resting-state functional magnetic resonance imaging articles published during the last 15 years were included comprising observations from 2,789 patients and 3,002 healthy controls.
Results.
Specific regional changes in DMN cohesiveness located in the anteromedial and posteromedial cortex emerged as shared and trans-diagnostic brain phenotypes. Disease-specific dysconnectivity was also identified. Unmedicated patients showed more DMN functional alterations, highlighting the importance of interventions targeting the functional integration of the DMN.
Conclusion.
This study highlights functional alteration in the major hubs of the DMN, suggesting common abnormalities in self-referential mental activity across psychiatric disorders.
While technology is beneficial in many ways for organizations, it also allows employees a plethora of new methods to engage in workplace mistreatment and other counterproductive work behavior (CWB). Thus, technology’s role in the changing nature of work includes contributing to deleterious organizational and employee wellbeing outcomes. This chapter focuses on newer cyber-CWB and cyber occupational health psychology (C-OHP) constructs that lead to these negative workplace effects, including cyber incivility, cyberbullying, cyberloafing, and cybersecurity behaviors. The extant literature in this nascent area suggests that many of these behaviors occur on a frequent basis in today’s workplace, and we provide recommendations to lessen the occurrence of C-CWB and C-OHP behaviors. We also discuss potential drawbacks of commonly employed deterrents of these behaviors, such as social media screening and workplace monitoring.