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The U.S. Department of Agriculture–Agricultural Research Service (USDA-ARS) has been a leader in weed science research covering topics ranging from the development and use of integrated weed management (IWM) tactics to basic mechanistic studies, including biotic resistance of desirable plant communities and herbicide resistance. ARS weed scientists have worked in agricultural and natural ecosystems, including agronomic and horticultural crops, pastures, forests, wild lands, aquatic habitats, wetlands, and riparian areas. Through strong partnerships with academia, state agencies, private industry, and numerous federal programs, ARS weed scientists have made contributions to discoveries in the newest fields of robotics and genetics, as well as the traditional and fundamental subjects of weed–crop competition and physiology and integration of weed control tactics and practices. Weed science at ARS is often overshadowed by other research topics; thus, few are aware of the long history of ARS weed science and its important contributions. This review is the result of a symposium held at the Weed Science Society of America’s 62nd Annual Meeting in 2022 that included 10 separate presentations in a virtual Weed Science Webinar Series. The overarching themes of management tactics (IWM, biological control, and automation), basic mechanisms (competition, invasive plant genetics, and herbicide resistance), and ecosystem impacts (invasive plant spread, climate change, conservation, and restoration) represent core ARS weed science research that is dynamic and efficacious and has been a significant component of the agency’s national and international efforts. This review highlights current studies and future directions that exemplify the science and collaborative relationships both within and outside ARS. Given the constraints of weeds and invasive plants on all aspects of food, feed, and fiber systems, there is an acknowledged need to face new challenges, including agriculture and natural resources sustainability, economic resilience and reliability, and societal health and well-being.
The coronavirus disease 2019 (COVID-19) pandemic has resulted in shortages of personal protective equipment (PPE), underscoring the urgent need for simple, efficient, and inexpensive methods to decontaminate masks and respirators exposed to severe acute respiratory coronavirus virus 2 (SARS-CoV-2). We hypothesized that methylene blue (MB) photochemical treatment, which has various clinical applications, could decontaminate PPE contaminated with coronavirus.
The 2 arms of the study included (1) PPE inoculation with coronaviruses followed by MB with light (MBL) decontamination treatment and (2) PPE treatment with MBL for 5 cycles of decontamination to determine maintenance of PPE performance.
MBL treatment was used to inactivate coronaviruses on 3 N95 filtering facepiece respirator (FFR) and 2 medical mask models. We inoculated FFR and medical mask materials with 3 coronaviruses, including SARS-CoV-2, and we treated them with 10 µM MB and exposed them to 50,000 lux of white light or 12,500 lux of red light for 30 minutes. In parallel, integrity was assessed after 5 cycles of decontamination using multiple US and international test methods, and the process was compared with the FDA-authorized vaporized hydrogen peroxide plus ozone (VHP+O3) decontamination method.
Overall, MBL robustly and consistently inactivated all 3 coronaviruses with 99.8% to >99.9% virus inactivation across all FFRs and medical masks tested. FFR and medical mask integrity was maintained after 5 cycles of MBL treatment, whereas 1 FFR model failed after 5 cycles of VHP+O3.
MBL treatment decontaminated respirators and masks by inactivating 3 tested coronaviruses without compromising integrity through 5 cycles of decontamination. MBL decontamination is effective, is low cost, and does not require specialized equipment, making it applicable in low- to high-resource settings.
The archaeological site of Saruq al-Hadid, Dubai, United Arab Emirates, presents a long sequence of persistent temporary human occupation on the northern edge of the Rub’ al-Khali desert. The site is located in active dune fields, and evidence for human activity is stratified within a deep sequence of natural dune deposits that reflect complex taphonomic processes of deposition, erosion and reworking. This study presents the results of a program of radiocarbon (14C) and thermoluminescence dating on deposits from Saruq al-Hadid, allied with studies of material remains, which are amalgamated with the results of earlier absolute dating studies provide a robust chronology for the use of the site from the Bronze Age to the Islamic period. The results of the dating program allow the various expressions of human activity at the site—ranging from subsistence activities such as hunting and herding, to multi-community ritual activities and large scale metallurgical extraction—to be better situated chronologically, and thus in relation to current debates regarding the development of late prehistoric and early historic societies in southeastern Arabia.
Since the 1970s, a stretch of Broadway Avenue in Wichita, Kansas, has seen the growth of both Latino and Asian businesses. Using mapping, data analysis, and historical research, this study compares the growth of ethnic entrepreneurship between both populations. The results not only reveal similarities but also illustrate the degree to which ethnic entrepreneurship varies, depending on a population’s situation in a given location.
Alzheimer’s disease (AD) has long been recognized as a heterogeneous illness, with a common clinical presentation of progressive amnesia and less common “atypical” clinical presentations, including syndromes dominated by visual, aphasic, “frontal,” or apraxic symptoms. Our knowledge of atypical clinical phenotypes of AD comes from clinicopathologic studies, but with the growing use of in vivo molecular biomarkers of amyloid and tau pathology, we are beginning to recognize that these syndromes may not be as rare as once thought. When a clinician is evaluating a patient whose clinical phenotype is dominated by progressive aphasia, complex visual impairment, or other neuropsychiatric symptoms with relative sparing of memory, the differential diagnosis may be broader and a confident diagnosis of an atypical form of AD may require the use of molecular biomarkers. Despite the evolving sophistication in our diagnostic tools, and the acknowledgment of atypical AD syndromes in the 2011 revised diagnostic criteria for AD, the assessment of such patients still poses substantial challenges. We use a case-based approach to review the clinical and imaging phenotypes of a series of patients with typical and atypical AD, and discuss our current approach to their evaluation. One day, we hope that regardless of whether a patient exhibits typical or atypical symptoms of AD pathology, we will be able to identify the condition at a prodromal phase and institute a combination of symptomatic and disease-modifying therapies to support cognitive processes, function, and behavior, and slow or halt progression to dementia.
The rivers of central Australia rise in the MacDonnell Ranges and flow out across broad, low-relief plains into the surrounding desert. The stratigraphy of the Ross River plain records the areal extent and frequency of Holocene floods. This floodout plain is underlain by deeply weathered alluvial deposits, characterized by red earth soils dated by thermoluminesence at >59,000 yr. This old alluvium is covered by a sheet-like deposit of very silty sand of probable eolian origin dated by thermoluminesence at 9200 ± 900 yr. The oldest Holocene alluvium occurs as broad, low-relief bars and levee deposits flanking the modem channel and as low-relief long-wavelength bedforms that fan out across the plain. This deposit resulted from a flood flow, up to 10 km wide, that covered the entire plain. Evidence for several large floods between 1500 and 700 yr B.P. is also preserved in a 500- to 1500-m-wide paleochannel. Thus, the surface features on the floodout plains are the product of a few rare large flood events. This paleohydrologic record is additional evidence of the dynamic nature of the hydrometerological regime of central Australia.
Thirty-five sand hills that form six scattered groups rise abruptly from the flat late Pleistocene coastal plain in southeastern Louisiana. New studies confirm their eolian origin. For the first time, several late Wisconsin to early Holocene episodes of arid climate conditions have been recognized and dated in this currently humid warm-temperate subtropical region. Periods of dune formation and reactivation (28,800 to 7900 yr B.P.) were determined by the thermoluminescence method. The onset of the current climate in this Gulf coastal region postdates early Holocene time. The textural and structural homogeneity of the ridge lithosomes, good sorting of their sand fraction, and the dominantly orange hues of the dune sediments contrast with the underlying yellowish–brown to light-brown sandy silts and the well-stratified, occasionally gravelly sands of the underlying alluvial Prairie Formation. Sharply defined, unconformable ridge bases; symmetrical, oval, occasionally parabolic mound shapes; and steep slopes confirm the dune origins. The dominant orientations of ridges and ridge chains clearly reflect paleowind directions. Age comparison with dunes of the lower Mississippi Valley, the northeastern–eastern Gulf of Mexico coast, and south Atlantic coastal areas confirms the existence of at least seasonally dry climate conditions from early Wisconsin to middle Holocene times. The onset of the modern humid-subtropical climate phase in this region thus dates back only to the middle Holocene.
Thermoluminescence (TL) age determinations of alluvial sediments in the tropics are evaluated by comparison with U/Th age determinations of pedogenic accumulations in the alluvium of the lower Gilbert River, a large fan delta in the wet-dry tropics of northern Queensland, Australia. This study extends U/Th dating by applying it not only to calcretes, but also to Fe/Mn oxyhydroxide/oxide accumulations. While a direct correlation cannot be made between U/Th dates from secondary minerals and TL dates from the host sediments, both sets of data show broad consistency. In addition to providing a minima for acceptable TL ages, U/Th dates are useful for determining the chronology of pedogenesis/diagenesis. They show that calcretes and ferricretes have formed under similar climatic conditions in the wet-dry tropics of northern Australia during the late pleistocene. Beneath about 5–12 m the Gilbert fan delta consists of an extensive sand body older than 85,000 yr and probably about 120,000 yr in age, representative of a period of major fluvial activity not repeated since this time. Above are muds and fine sandy muds that extend uninterrupted to the present surface except in the downstream fan where they are bisected by a thin unit of medium sand that TL dates at 40,000–50,000 yr B.P. A system of sandy distributary channels over the fan surface represents an early Holocene fluvial phase probably more active than at present.
Acute kidney injury after cardiac surgery is a frequent and serious complication among children with congenital heart disease (CHD) and adults with acquired heart disease; however, the significance of kidney injury in adults after congenital heart surgery is unknown. The primary objective of this study was to determine the incidence of acute kidney injury after surgery for adult CHD. Secondary objectives included determination of risk factors and associations with clinical outcomes.
This single-centre, retrospective cohort study was performed in a quaternary cardiovascular ICU in a paediatric hospital including all consecutive patients ⩾18 years between 2010 and 2013.
Data from 118 patients with a median age of 29 years undergoing cardiac surgery were analysed. Using Kidney Disease: Improving Global Outcome creatinine criteria, 36% of patients developed kidney injury, with 5% being moderate to severe (stage 2/3). Among higher-complexity surgeries, incidence was 59%. Age ⩾35 years, preoperative left ventricular dysfunction, preoperative arrhythmia, longer bypass time, higher Risk Adjustment for Congenital Heart Surgery-1 category, and perioperative vancomycin use were significant risk factors for kidney injury development. In multivariable analysis, age ⩾35 years and vancomycin use were significant predictors. Those with kidney injury were more likely to have prolonged duration of mechanical ventilation and cardiovascular ICU stay in the univariable regression analysis.
We demonstrated that acute kidney injury is a frequent complication in adults after surgery for CHD and is associated with poor outcomes. Risk factors for development were identified but largely not modifiable. Further investigation within this cohort is necessary to better understand the problem of kidney injury.
The study of the Bom Santo Cave (central Portugal), a Neolithic cemetery, indicates a complex social, palaeoeconomic, and population scenario. With isotope, aDNA, and provenance analyses of raw materials coupled with stylistic variability of material culture items and palaeogeographical data, light is shed on the territory and social organization of a population dated to 3800–3400 cal BC, i.e. the Middle Neolithic. Results indicate an itinerant farming, segmentary society, where exogamic practices were the norm. Its lifeway may be that of the earliest megalithic builders of the region, but further research is needed to correctly evaluate the degree of this community's participation in such a phenomenon.
We present the current standing of an investigation into the structure of the Milky Way. We use smoothed particle hydrodynamics (SPH) to simulate the ISM gas in the Milky Way under the effect of a number of different gravitational potentials representing the spiral arms and nuclear bars, both fixed and time-dependent. The gas is subject to ISM cooling and chemistry, enabling us to track the CO and HI density. We use a 3D grid-based radiative transfer code to simulate the emission from the SPH output, allowing for the construction of synthetic longitude-velocity maps as viewed from the Earth. By comparing these maps with the observed emission in CO and HI from the Milky Way ([Dame et al. 2001, Kalberla et al. 2005]), we can infer the arm/bar geometry that provides a best fit to our Galaxy. By doing so we aim to answer key questions concerning the morphology of the Milky Way such as the number of the spiral arms, the pattern speeds of the bar(s) and arms, the pitch angle of the arms and shape of the bar(s).