We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
To send content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to .
To send content items to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Find out more about the Kindle Personal Document Service.
Primary ciliary dyskinesia and heterotaxy are rare but not mutually exclusive disorders, which result from cilia dysfunction. Heterotaxy occurs in at least 12.1% of primary ciliary dyskinesia patients, but the prevalence of primary ciliary dyskinesia within the heterotaxy population is unknown. We designed and distributed a web-based survey to members of an international heterotaxy organisation to determine the prevalence of respiratory features that are common in primary ciliary dyskinesia and that might suggest the possibility of primary ciliary dyskinesia. A total of 49 members (25%) responded, and 37% of the respondents have features suggesting the possibility of primary ciliary dyskinesia, defined as (1) the presence of at least two chronic respiratory symptoms, or (2) bronchiectasis or history of respiratory pathogens suggesting primary ciliary dyskinesia. Of the respondents, four completed comprehensive, in-person evaluations, with definitive primary ciliary dyskinesia confirmed in one individual, and probable primary ciliary dyskinesia identified in two others. The high prevalence of respiratory features compatible with primary ciliary dyskinesia in this heterotaxy population suggests that a subset of heterotaxy patients have dysfunction of respiratory, as well as embryonic nodal cilia. To better assess the possibility of primary ciliary dyskinesia, heterotaxy patients with chronic oto-sino-respiratory symptoms should be referred for a primary ciliary dyskinesia evaluation.
In the waning days of the 1924–5 school year, John Thomas Scopes, a young teacher filling in for the regular biology teacher in Dayton, Tennessee, assigned reading from Hunter's Civic biology to prepare students for their final examination. This came after Tennessee had passed a law in March 1925 outlawing the teaching of evolution. Scopes was put on trial and convicted, and subsequently became a symbol of the (perceived) ongoing warfare between science and religion. Scopes was hailed by some as a martyr to intellectual freedom, compared to the likes of Socrates and Galileo. Often linked with the phrase ‘Monkey Trial’, the name ‘Scopes’ also became a label of derision by those who saw in evolution an irreligious and immoral doctrine. It has been immortalized in folk songs, on Broadway, and on the silver screen, and there is no doubt that the Scopes trial remains one of the best-known and most significant events in the history of science and religion in the United States. Because of two men – Clarence Darrow and William Jennings Bryan, whose debate over the truth of the Bible and its relationship to science captivated the country and was reported throughout the world – the Scopes trial has frequently been described as ‘the trial of the century’. Even as the twentieth century has given way to the twenty-first, interest in the trial has shown no sign of waning.
Email your librarian or administrator to recommend adding this to your organisation's collection.