Skip to main content Accessibility help
×
Hostname: page-component-848d4c4894-m9kch Total loading time: 0 Render date: 2024-04-30T23:54:54.490Z Has data issue: false hasContentIssue false

10 - Poorly differentiated thyroid carcinoma

Published online by Cambridge University Press:  05 September 2014

Grace C. H. Yang
Affiliation:
Weill Medical College of Cornell University
Get access
Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2013

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bongiovanni, M, Faquin, WC.Poorly differentiated thyroid carcinoma. Ch. 10 in: Ali, SZ, Cibas, ES (eds.) The Bethesda System for Reporting Thyroid Cytopathology: Definitions, Criteria, and Explanatory Notes. New York: Springer; 2010: 129–38.CrossRefGoogle Scholar
Sakamoto, A, Kasai, N, Sugano, H.Poorly differentiated carcinoma of the thyroid: A clinicopathologic entity for a high-risk group of papillary and follicular carcinomas. Cancer 1983; 52: 1849–55.3.0.CO;2-X>CrossRefGoogle ScholarPubMed
Carcangiu, ML, Zampi, G, Rosai, J.Poorly differentiated (“insular”) thyroid carcinoma: A reinterpretation of Langhans' “wuchernde Struma.” Am J Surg Pathol 1984; 8: 655–68.CrossRefGoogle ScholarPubMed
Sobrinho-Simoes, M, Albores-Saavedra, J, Tallini, G, et al. Poorly differentiated carcinoma. In: DeLellis, RA, Lloyd, RV, Heitz, PU, Eng, C (eds.) Pathology and Genetics of Tumours of Endocrine Organs. World Health Organization Classification of Tumours. Lyon: IARC Press, 2004: 73–6.Google Scholar
Volante, M, Landolfi, S, Chiusa, L, et al. Poorly differentiated carcinomas of the thyroid with trabecular, insular, and solid patterns: a clinicopathologic study of 183 patients. Cancer 2004; 100: 950–7.CrossRefGoogle ScholarPubMed
Volante, M, Collini, P, Nikiforov, YE, et al. Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approach. Am J Surg Pathol 2007; 31: 1256–64.CrossRefGoogle ScholarPubMed
Garcia-Rostan, G, Sobrinho-Simoes, M.Poorly differentiated thyroid carcinoma: an evolving entity. Diagn Histopathol 2011; 17: 114–23.CrossRefGoogle Scholar
Volante, M, Rapa, I, Gandhi, M, et al. RAS mutations are the predominant molecular alteration in poorly differentiated thyroid carcinomas and bear prognostic impact. J Clin Endocrinol Metab 2009; 94: 4735–41.CrossRefGoogle ScholarPubMed
Nikiforov, YE.Genetic alterations involved in the transition from well-differentiated to poorly differentiated and anaplastic thyroid carcinomas. Endocr Pathol 2004; 15: 319–27.CrossRefGoogle ScholarPubMed
Nikiforov, YE, Biddinger, PW, Thompson, LDR.Diagnostic Pathology and Molecular Genetics of the Thyroid. Philadelphia, PA: Lippincott, Williams & Wilkins, 2009.Google ScholarPubMed
Ito, Y, Hirokawa, M, Fukushima, M, et al. Prevalence and prognostic significance of poor differentiation and tall cell variant in papillary carcinoma in Japan. World J Surg 2008; 32: 1535–43.CrossRefGoogle ScholarPubMed
Papotti, M, Botto, Micca F, Favero, A, et al. Poorly differentiated thyroid carcinomas with primordial cell component: A group of aggressive lesions sharing insular, trabecular, and solid patterns. Am J Surg Pathol 1993; 17: 291–301.CrossRefGoogle ScholarPubMed
Flynn, SD, Forman, BH, Stewart, AF, Kinder, BK.Poorly differentiated (“insular”) carcinoma of the thyroid gland: an aggressive subset of differentiated thyroid neoplasms. Surgery 1988; 104: 963–70.Google ScholarPubMed
Pellegriti, G, Giuffrida, D, Scollo, C, et al. Long-term outcome of patients with insular carcinoma of the thyroid: the insular histotype is an independent predictor of poor prognosis. Cancer 2002; 95: 2076–85.CrossRefGoogle ScholarPubMed
Sironi, M, Collini, P, Cantaboni, A.Fine needle aspiration cytology of insular thyroid carcinoma: A report of four cases. Acta Cytol 1992; 36: 435–9.Google ScholarPubMed
Bongiovanni, M, Bloom, L, Krane, JF, et al. Cytomorphologic features of poorly differentiated thyroid carcinoma: A multi-institutional analysis of 40 cases. Cancer (Cancer Cytopathol) 2009; 117: 185–94.CrossRefGoogle ScholarPubMed
Guiter, GE, Auger, M, Ali, SZ, Allen, EA, Zakowski, MF.Cytopathology of insular carcinoma of the thyroid. Cancer (Cancer Cytopathol) 1999; 87: 196–202.3.0.CO;2-P>CrossRefGoogle ScholarPubMed
Bongiovanni, M, Sadow, PM, Faquin, WC.Poorly differentiated thyroid carcinoma: A cytologic-histologic review. Adv Anat Pathol 2009; 16: 283–9.CrossRefGoogle ScholarPubMed
Pietribiasi, F, Sapino, A, Papotti, M, Bussolati, G.Cytologic features of poorly differentiated “insular” carcinoma of the thyroid, as revealed by fine-needle aspiration biopsy. Am J Clin Pathol 1990; 94: 687–92.CrossRefGoogle ScholarPubMed
Nguyen, GK, Akin, MR.Cytopathology of insular carcinoma of the thyroid. Diagn Cytopathol 2001; 25: 325–30.CrossRefGoogle ScholarPubMed
Oertel, YC, Miyahara-Felipe, L.Cytologic features of insular carcinoma of the thyroid: A case report. Diagn Cytopathol 2006; 34: 572–5.CrossRefGoogle ScholarPubMed
Layfield, LJ, Gopez, EV.Insular carcinoma of the thyroid: Report of a case with intact insulae and microfollicular structures. Diagn Cytopathol 2000; 23: 409–13.3.0.CO;2-5>CrossRefGoogle ScholarPubMed
Kuhel, WI, Kutler, DI, Santos-Buch, CA.Poorly differentiated insular thyroid carcinoma: A case report with identification of intact insulae with fine needle aspiration biopsy. Acta Cytol 1998; 42: 991–7.CrossRefGoogle ScholarPubMed
Erkilic, S, Kocer, NE.Insular carcinoma of the thyroid with uncommon cytologic features: Anisokaryotic cells and microfollicles containing dense colloid. Pathol Res Pract 2006; 202: 389–93.CrossRefGoogle ScholarPubMed
Jain, S, Kumar, N, Gupta, S, Sodhani, P, Aggarwal, AK.Insular carcinoma of the thyroid with a predominant microfollicular pattern: A diagnostic pitfall on cytology. Acta Cytol 2004; 48: 111–13.Google ScholarPubMed
Gong, Y, Krishnamurthy, S.Fine-needle aspiration of an unusual case of poorly differentiated insular carcinoma of the thyroid. Diagn Cytopathol 2005; 32: 103–7.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×