Programmed Cell Death in the Yeast <span class='italic'>Saccharomyces cerevisiae</span>

Valter D. Longo; Cristina Mazzoni

doi:10.1017/CBO9780511976094.033

33 - Programmed Cell Death in the Yeast Saccharomyces cerevisiae

from Part III - Cell Death in Nonmammalian Organisms

Published online by Cambridge University Press: 07 September 2011

Valter D. Longo and

Edited by

Douglas R. Green: Affiliation:
St. Jude Children's Research Hospital, Memphis, Tennessee
Valter D. Longo: Affiliation:
University of Southern California
Cristina Mazzoni: Affiliation:
University of Rome
John C. Reed: Affiliation:
Sanford-Burnham Medical Research Institute, La Jolla, California

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Summary

The yeast Saccharomyces cerevisiae is one of the most studied model systems for molecular and cellular biology. In 1996, it became the first eukaryotic organism to have a completely sequenced genome (Dujon, 1996; Goffeau et al., 1996), which led to a number of valuable and widely accessed databases. Among its features is the short generation time (usually 90–120 minutes) and the ability to grow at various temperatures in relatively inexpensive media. Moreover, many of its genes are well characterized, thanks in part to its amenability to modifications such as gene disruption, gene marking, mutations, or gene-dosage modifications. Because of these advantageous features, it has become the model organism of choice for many investigators in fields ranging from basic biology to biomedical research.

Type: Chapter
Information: Apoptosis
Physiology and Pathology
, pp. 389 - 396

DOI: https://doi.org/10.1017/CBO9780511976094.033 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2011

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33 - Programmed Cell Death in the Yeast Saccharomyces cerevisiae

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