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Fluid Therapy

Mazyar Kanani
Affiliation:
British Heart Foundation
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Summary

How do you assess clinically the state of hydration?

Examining the fluid chart for the input/output balance

Examining the patient specifically looking for the state of the tissues

Skin turgor

Dry mouth

Sunken eyes

Concentrated urine in the catheter

Possible tachycardia and hypotension

Measure the central venous pressure (CVP), and determine the response to a fluid challenge. If there is ‘underfilling’, the CVP will not increase in response to the challenge

What are the main fluid compartments of the body, and what are their volumes?

The fluid compartments are

Intracellular compartment: 28l

Extracellular compartment: 14l

Plasma: 3l

Interstitium: 10l

Transcellular: 1l

Therefore the total body water is 42l, which makes up ∼60% of the body weight of a 70 kg male and 55–60% for females.

How can the percentage fall of the extracellular fluid volume be calculated?

In the case of loss of extracellular fluid (ECF), the concentration of the plasma albumin increases depending on the amount of water lost during dehydration. The resulting rise in the albumin concentration can be used to calculate the % fall in the ECF volume.

where A1 initial albumin concentration; A2 = albumin concentration following loss of volume.

How can the percentage fall in the plasma volume be calculated?

In situations of loss of plasma, there is a loss of plasma protein, but not of blood. Thus, the haematocrit increases in proportion to the volume of plasma lost. Measurements of the haematocrit are therefore useful in calculating the % fall in the plasma volume.

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Publisher: Cambridge University Press
Print publication year: 2002

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  • Fluid Therapy
  • Mazyar Kanani, British Heart Foundation
  • Book: Surgical Critical Care Vivas
  • Online publication: 05 July 2011
  • Chapter DOI: https://doi.org/10.1017/CBO9780511584251.031
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  • Fluid Therapy
  • Mazyar Kanani, British Heart Foundation
  • Book: Surgical Critical Care Vivas
  • Online publication: 05 July 2011
  • Chapter DOI: https://doi.org/10.1017/CBO9780511584251.031
Available formats
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Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Fluid Therapy
  • Mazyar Kanani, British Heart Foundation
  • Book: Surgical Critical Care Vivas
  • Online publication: 05 July 2011
  • Chapter DOI: https://doi.org/10.1017/CBO9780511584251.031
Available formats
×