Skip to main content Accessibility help
×
Hostname: page-component-7479d7b7d-q6k6v Total loading time: 0 Render date: 2024-07-10T19:30:42.846Z Has data issue: false hasContentIssue false

Chapter 6 - Pregnancy Termination

from Part I - ANTEPARTUM

Published online by Cambridge University Press:  07 May 2010

John Patrick O'Grady
Affiliation:
Tufts University, Massachusetts
F. P. Bailey
Affiliation:
Assistant Professor, Department of Obstetrics and Gynecology Tufts University School of Medicine Boston
Heather Z. Sankey
Affiliation:
Assistant Professor, Department of Obstetrics and Gynecology Tufts University School of Medicine Boston
Get access

Summary

This chapter reviews the history and epidemiology of modern pregnancy termination. In this review, the surgical and medical techniques appropriate for various gestational ages are presented, potential complications are considered, and the psychological issues surrounding abortion are discussed. Most women requesting termination of pregnancy are self-referred. Physicians who care for pregnant patients should assess the patient's attitudes toward the gestation at the time of the first prenatal visit. The initial assessment of gestational age is based on the last reported menstrual period and the physical examination. The method chosen for pregnancy termination depends on the period of gestation, the experience and preference of the operator, and the extent to which safe options are available that fit the patient's desires. The most common operative complication of pregnancy termination is uterine perforation. Failure to interrupt an intrauterine pregnancy occurs in less than 0.5 percent of suction-curettage patients.
Type
Chapter
Information
Operative Obstetrics , pp. 119 - 144
Publisher: Cambridge University Press
Print publication year: 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Riddle, JM, Estes, JW, Russell, JC.Ever since Eve…birth control in the ancient world. Archaeology. 1993;47:29–35.Google Scholar
Shain, RN.A cross-cultural history of abortion. Clin Obstet Gynecol. 1986;13:1–17.Google ScholarPubMed
Kunis, H, Rosenfield, A.Abortion: A legal and public health perspective. Annu Rev Publ Health. 1991; 12:361–382.CrossRefGoogle Scholar
Statistics and Computer Resources Branch, Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control. Abortion surveillance: Preliminary data – United States, 2003. MMWR. 2005;54:1–31.
Henshaw, SK.The accessibility of abortion services in the United States. Fam Plann Perspect. 1991;23:246–252.CrossRefGoogle ScholarPubMed
Kaali, SG, Szigetvari, I, Bartfai, A, Feinman, M.Laparoscopic sterilization combined with dilation and evacuation up to 18 weeks' gestation. J Reprod Med. 1989; 34:463–464.Google Scholar
Landy, U.Abortion counseling: A new component of medical care. Clin Obstet Gynecol. 1986;13:33–41.Google ScholarPubMed
Steinberg, TN: Abortion counseling: To benefit maternal health. Am J Law Med 1989;15:483–517.Google ScholarPubMed
Rosenthal M. Elective abortion. In: Grady, O' JP, Rosenthal, M (eds): Obstetrics: Psychological and Psychiatric Syndromes. New York: Elsevier, 1992, pp. 307–318.Google Scholar
Rosenfeld, JA.Emotional responses to therapeutic abortion. Am Fam Physician. 1992;45:137–140.Google ScholarPubMed
Brown H. Pregnancy termination. In: Plauché, WC, Morrison, JC, Sullivan, O' MJ (eds): Surgical Obstetrics. Philadelphia: Harcourt Brace Jovanovich, 1992; pp. 119–131.Google Scholar
Castadot, RG.Pregnancy termination: Techniques, risks, and complications and their management. Fertil Steril. 1986;45:5–17.Google ScholarPubMed
Acharya, G, Morgan, H, Paramanantham, L, Fernando, R.A randomized controlled trial comparing surgical termination of pregnancy with and without continuous ultrasound guidance. Eur J Obstet Gynecol Reprod Biol. 2004;114:69–74.CrossRefGoogle ScholarPubMed
American College of Obstetricians and Gynecologists. Antibiotic Prophylaxis for Gynecologic Procedures Practice Bulletin, Number 74, July, 2006.
Jonasson, A, Larsson, B, Bygdeman, S, Forsum, U.The influence of cervical dilatation by Laminaria tent and with Hegar dilators on the intrauterine microflora and the rate of postabortal pelvic inflammatory disease. Acta Obstet Gynecol Scand. 1989;68(5):405–410.CrossRefGoogle ScholarPubMed
Lichtenberg, ES, Shott, S.A randomized clinical trial of prophylaxis for vacuum abortion: 3 versus 7 days of doxycycline. Obstet Gynecol. 2003 Apr;101(4):726–731.Google Scholar
Suprapto, K, Reed, S.Naproxen sodium for pain relief in first-trimester abortion. Am J Obstet Gynecol. 1984 Dec;150(8) 1000–1001.CrossRefGoogle Scholar
Stubblefield PG. Surgical techniques for first-trimester abortion. In: Gabbe, SG, Niebyl, JR, Simpson, JL (eds): Obstetrics: Normal and Problem Pregnancies, 2nd ed. New York: Churchill Livingstone, 1991, pp 1303–1332.Google Scholar
Burnett, M, Corbett, C, Gertenstein, R.A randomized trial of Laminaria tents versus vaginal misoprostol for cervical ripening in first-trimester surgical abortion. J Obstet Gynaecol Can. 2005 Jan;27(1):38–42.CrossRefGoogle Scholar
Stubblefield, PG, Carr-Ellis, S, Borgatta, L.Methods for induced abortion Obstet Gynecol. 2004 Jul; 104(1):174–185.CrossRef
Sharma, S, El-Refacy, H.The use of misoprostol as a cervical ripening agent in operative hysteroscopy. Am J Obstet Gynecol. 2003 Jan;188(1):297–298.CrossRefGoogle Scholar
Goldenburg, AB, Dean, G, Kang, M, Youssof, S, Darney, PD.Manual versus electric vacuum aspiration for early first-trimester abortion: A controlled study of complication rates. Obstet Gynecol. 2004 Jan;103(1):101–107.Google Scholar
Felding, C, Mikkelsen, AL, Villerslev, L.First-trimester legal induced abortions: The amount of aspirated tissue in relation to gestational age. Arch Gynecol Obstet. 1991;249:149–151.CrossRefGoogle ScholarPubMed
Laufe LE. Menstrual regulation. In: Zatuchni, GI, Laferla, JJ, Sciara, JJ (eds): Gynecology and Obstetrics, vol 6. Philadelphia: JB Lippincott, 1990. 56; 1–6.Google Scholar
Edward, J, Creinin, MD.Surgical abortion for gestations of less than 6 weeks. Current Problems in Obstetrics, Gynecology, and Fertility. 1997;20:11–19.Google Scholar
Paul, M, Mitchell, C, Rogers, AJ, Fox, MC, Lackie, EG.Early surgical abortion: Efficacy and safety. Am J Obstet Gynecol. 2002 Aug;187(2):407–411.CrossRefGoogle Scholar
Darney, PD, Atkinson, E, Hirabayashi, K.Uterine perforation during second-trimester abortion by cervical dilation and instrumental extraction: A review of 15 cases. Obstet Gynecol. 1990;75:441–444.Google ScholarPubMed
Cates, W, Shulz, KF, Grimes, DA, Horowitz, AJ, Lyon, FA, Kravitz, FH, Frisch, MJ.Dilatation and evacuation procedures and second-trimester abortions: The role of physician skill and hospital setting. JAMA. 1982 Aug 6;248(5):559–563.CrossRefGoogle Scholar
Peterson, WF, Berry, FN, Grace, MR, Gulbranson, CL.Second-trimester abortion by dilatation and evacuation: An analysis of 11,747 cases. Obstet Gynecol. 1983 Aug;62(2):185–190.Google Scholar
Dark, AC, Miller, L, Kathenbeutel, RL, Mandel, L.Obesity and second-trimester abortion by dilation and evacuation. J Reprod Med. 2002;47:226–230.Google ScholarPubMed
Goldenberg, RL, Davis, RO, Hill, D.The use of real-time ultrasound as an aid during difficult therapeutic abortion procedures. Am J Obstet Gynecol. 1984;148:826–827.CrossRefGoogle ScholarPubMed
Romero, R, Copel, JA, Jeanty, P, Reece, EA, Reiss, R, Hobbins, JC.Sonographic monitoring to guide the performance of postabortal uterine curettage. Am J Obstet Gynecol. 1985 Jan;151(1): 51–53.CrossRefGoogle Scholar
Darney, PD, Sweet, RL.Routine intraoperative ultrasonography for second-trimester abortion reduces incidence of uterine perforation. J Ultrasound Med. 1989 Feb;8(2):71–75.CrossRefGoogle Scholar
Schulman H. Second-trimester abortion: Techniques and complications. In: Zatuchni, GI, Laferla, JJ, Sciara, JJ (eds): Gynecology and Obstetrics, vol 6. Philadelphia: JB Lippincott, 1990; pp. 1–11; 64.Google Scholar
Grimes, DA, Ray, IG, Middleton, CJ: Lamicel versus laminaria for cervical dilation before second-trimester abortion: A randomized clinical trial. Obstet Gynecol. 1987 Jun;69(6):887–889.Google Scholar
Wells, EC, Hulka, JF.Cervical dilation: A comparison of Lamicel and Dilapan. Am J Obstet Gynecol. 1989;161:1124–1126.CrossRefGoogle ScholarPubMed
Goldberg, AB, Drey, EA, Witaker, AK, Kang, M, Meckstroth, KR, Darney, PD.Misoprostol compared with Laminaria before early second-trimester surgical abortion: A randomized trial. Obstet Gynecol. 2005 Aug;106(2):234–241.CrossRefGoogle Scholar
Lichtenberg, S, Scott, S.Clinical trial of prophylaxis for vacuum abortion: 3 versus 7 days of doxycycline. Obstet Gynecol. 2003;101:726–731.Google ScholarPubMed
Schulz, KF, Grimes, DA, Christensen, DD.Vasopressin reduces blood loss from second-trimester dilation and evacuation. Lancet. 1985 Aug 17;2(8451):353–356.CrossRefGoogle Scholar
Schulman, L, Lig, F.Termination of pregnancy: Second trimester. http://www.UptoDate.com.
Kruetner AK. Hysterotomy and hysterectomy for abortion: In: Zatuchni, GI, Laferla, JJ, Sciara, JJ (eds): Gynecology and Obstetrics, vol 6. Philadelphia: JB Lippincott, 1990;61: 1–9.Google Scholar
Kovács, L.Future direction of abortion technology. Baillières Clin Obstet Gynecol. 1990 Jun;4(2):407–415.CrossRefGoogle Scholar
Grimes, D, Mishell, D, Shoupe, D, Lacarra, M: Early abortion with a single dose of antiprogestin RU-486. Am J Obstet Gynecol. 1988; Jun;158(6 Pt 1):1307–1312.CrossRefGoogle ScholarPubMed
Schaff, EA, Eisinger, SH, Stadalius, LS, Franks, P, Gore, BZ, Poppema, S.Low-dose mifepristone 200 mg and vaginal misoprostol for abortion. Contraception. 1999 Jan;59(1):1–6.CrossRefGoogle Scholar
Schaff, EA, Fielding, SL, Eisinger, SH, Stadalius, LS, Fuller, L.Low-dose mifepristone followed by vaginal misoprostol at 48 hours for abortion up to 63 days. Contraception. 2000 Jan;61(1):41–46.CrossRefGoogle Scholar
Schaff, EA, Fielding, SL, Westhoff, C.Randomized trial of oral versus vaginal misoprostol at one day after mifepristone for early medical abortion. Contraception. 2001 Aug;64(2):81–85.CrossRefGoogle Scholar
Guest, J, Chien, PF, Thomson, MA, Kosseim, ML.Randomised controlled trial comparing the efficacy of same-day administration of mifeprisone and misoprostol for termination of pregnancy with the standard 36- to 48-hour protocol. BJOG. 2007 Feb;114(2):207–215.CrossRefGoogle Scholar
Bogaert, LJ, Sedibe, TM.Efficacy of a single misoprostol regimen in the first- and second-trimester termination of pregnancy. J Obstet Gynaecol. 2007 Jul;27(5):510–512.CrossRefGoogle Scholar
Khazardoost, S, Hantouschzadeh, S, Madani, MM.A randomised trial of two regimens of vaginal misoprostol to manage termination of pregnancy of up to 16 weeks. Aust N Z J Obstet Gynaecol. 2007 Jun; 47(3):226–229.CrossRefGoogle Scholar
Nilas, L, Glavind-Kristensen, M, Vejborg, T, Knudsen, UB.One- or two-day mifepristone-misoprostol interval for second-trimester abortion. Acta Obstet Gynecol Scand. 2007;86(9):1117–1121.CrossRefGoogle ScholarPubMed
Pymar, HC, Creinin, MD, Schwartz, JL.Mifepristone followed on the same day by vaginal misoprostol for early abortion between 50 and 63 days' gestation. Contraception. 2001 Aug;64(2):87–92.CrossRefGoogle Scholar
Fox, MC, Creinin, MD, Harweed, B.Mifepristone followed on the same day by vaginal misoprostol for early abortion between 50 and 63 days gestation. Contraception. 2002 Oct;66(4):225–229.CrossRefGoogle Scholar
FDA Public Health Advisory. Sepsis and Medical Abortion Update, March 17, 2006.
Owen, J, Hauth, JC.Concentrated oxytocin plus low-dose prostaglandin E2 compared with prosta- glandin E2 vaginal suppositories for second- trimester pregnancy termination. Obstet Gynecol. 1996 Jul; 88(1):110–113.CrossRefGoogle Scholar
Jain, JK, Mishell, DR.A comparison of intravaginal misoprostol with prostaglandin E2 for termination of second-trimester pregnancy. N Engl J Med. 1994 Aug;331(5):290–293.CrossRefGoogle Scholar
Herabutya, Y, O-Prasertsawat, P.Second-trimester abortion using intravaginal misoprostol. Int J Gynecol Obstet. 1998 Feb;60(2):161–165.CrossRefGoogle Scholar
Su, L, Biswas, A, Choolani, M, Kalaichelvan, V, Singh, K.A prospective randomized comparison of vaginal misoprostol versus intra-amniotic prostaglandins for midtrimester termination of pregnancy. Am J Obstet Gynecol. 2005 Oct;193(4):1410–1414.CrossRefGoogle Scholar
Ashok, P, Templeton, A, Wagaarachchi, P, Flett, G.Midtrimester medical termination of pregnancy: A review of 1002 consecutive cases. Contraception. 2004 Jan;69(1):51–58.CrossRefGoogle Scholar
Creinin, M.Methotrexate for abortion at 42 days' gestation. Contraception. 1993;48:519–525.CrossRefGoogle Scholar
Council Report: Induced termination of pregnancy before and after Roe v. Wade. JAMA. 1992;268: 3231–3239.CrossRef
Grimes, DA, Schulz, KF, Cates, WJ.Prevention of uterine perforation during curettage abortion. JAMA. 1984;251:2108–2111.CrossRefGoogle ScholarPubMed
Kaali, SG, Szigetvari, IA, Bartfai, GS.The frequency and management of uterine perforations during first-trimester abortions. Am J Obstet Gynecol. 1989;161:406–408.CrossRefGoogle ScholarPubMed
Hakim-Elahi, E, Tovell, HM, Burnhill, MS.Complications of first-trimester abortion: A report of 170,000 cases. Obstet Gynecol. 1990;76:129–135.Google ScholarPubMed
Hern WM. First-trimester abortion complications and their management. In: Zatuchni, GI, Laferla, JJ, Sciara, JJ (eds): Gynecology and Obstetrics, vol 6. Philadelphia: JB Lippincott, 1990;23: 1–9.Google Scholar
Hern WM. Long-term risks of induced abortion. In: Zatuchni, GI, Laferla, JJ, Sciara, JJ (eds): Gynecology and Obstetrics, vol 6. Philadelphia: JB Lippincott, 1990;52; 1–8.Google Scholar
Lazarus, A, Stern, R.Psychiatric aspects of pregnancy termination. Clin Obstet Gynecol. 1986;13:125–134.Google ScholarPubMed
Dagg, PKB.The psychological sequelae of therapeutic abortion – derived and computed. Am J Psychiatry. 1991;148:578–585.Google Scholar
Atrash, KK, MacKay, HT, Hogue, C JR.Ectopic pregnancy concurrent with induced abortion: Incidence and mortality. Am J Obstet Gynecol. 1990;162: 726–730.CrossRefGoogle ScholarPubMed
Reece, EA, Petrie, RH, Sirmans, MF, Finster, MTodd, WD.Combined intrauterine and extrauterine gestations: A review. Am J Obstet Gynecol. 1983; 146:323–330.CrossRefGoogle ScholarPubMed
Yuzpe, AA, Smith, RP, Rademaker, AW.A multicenter clinical investigation employing ethinyl estradiol combined with dl-norgestrel as a postcoital contraceptive agent. Fertil Steril. 1982 Apr;37(4): 508–513.CrossRefGoogle Scholar
Cheng, L, Gulmezoglu, AM, Oel, CJ, Piaggio, G, Ezcurra, E, Look, PF.Interventions for emergency contraception. Cochrane Database Syst Rev. 2004; (3).CrossRefGoogle ScholarPubMed
Allen, RH, Goldberg, AB.Emergency contraception: A clinical review. Clin Obstet Gynecol. 2007 Dec; 50(4):927–936.CrossRefGoogle Scholar
Johanson, E, Brache, V, Alvarez, F, Faundes, A, Cochon, L, Ranta, S, Lovern, M, Kumar, N.Pharmacokinetic study of different dosing regimens of levonorgestrel for emergency contraception in healthy women. Hum Reprod. 2002 Jun;17(6):1472–1476.CrossRefGoogle Scholar
Ngai, SW, Fan, S, Li, S, Cheng, L, Ding, J, Jing, X, Ng, EH, Ho, PC.A randomized trial to compare 24 h versus 12 h double-dose regimen of levonorgestrel for emergency contraception. Hum Reprod. 2005 Jan; 20(1):307–311.CrossRefGoogle Scholar
Lipsomb, GH.Medical Therapy for ectopic pregnancy. Semin Reprod Med. 2007;25(2):93–98.CrossRefGoogle Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×