Book contents
- Frontmatter
- Contents
- List of Contributors
- Foreword by Daniel R. Salomon
- Foreword by Robin Marks
- Foreword by Kathy Schwab
- Preface
- Acknowledgments
- SECTION ONE TRANSPLANT DERMATOLOGY: AN EVOLVING DYNAMIC FIELD
- Section Two Transplant Medicine and Dermatology
- Section Three Pathogenic Factors in Transplant Dermatology
- Section Four Cutaneous Effects of Immunosuppressive Medications
- Section Five Infectious Diseases of the Skin in Transplant Dermatology
- Section Six Benign and Inflammatory Skin Diseases in Transplant Dermatology
- 15 The Effects of Transplantation on Preexisting Dermatoses
- 16 Porokeratosis in Organ Transplant Recipients
- 17 Benign Cutaneous Neoplasms in Organ Transplant Recipients
- 18 Anogenital Cutaneous Disease in Organ Transplant Recipients
- 19 Cutaneous Graft versus Host Disease after Solid Organ Transplantation
- Section Seven Cutaneous Oncology in Transplant Dermatology
- Section Eight Special Scenarios in Transplant Cutaneous Oncology
- Section Nine Educational, Organizational, and Research Efforts in Transplant Dermatology
- Index
17 - Benign Cutaneous Neoplasms in Organ Transplant Recipients
from Section Six - Benign and Inflammatory Skin Diseases in Transplant Dermatology
Published online by Cambridge University Press: 18 January 2010
- Frontmatter
- Contents
- List of Contributors
- Foreword by Daniel R. Salomon
- Foreword by Robin Marks
- Foreword by Kathy Schwab
- Preface
- Acknowledgments
- SECTION ONE TRANSPLANT DERMATOLOGY: AN EVOLVING DYNAMIC FIELD
- Section Two Transplant Medicine and Dermatology
- Section Three Pathogenic Factors in Transplant Dermatology
- Section Four Cutaneous Effects of Immunosuppressive Medications
- Section Five Infectious Diseases of the Skin in Transplant Dermatology
- Section Six Benign and Inflammatory Skin Diseases in Transplant Dermatology
- 15 The Effects of Transplantation on Preexisting Dermatoses
- 16 Porokeratosis in Organ Transplant Recipients
- 17 Benign Cutaneous Neoplasms in Organ Transplant Recipients
- 18 Anogenital Cutaneous Disease in Organ Transplant Recipients
- 19 Cutaneous Graft versus Host Disease after Solid Organ Transplantation
- Section Seven Cutaneous Oncology in Transplant Dermatology
- Section Eight Special Scenarios in Transplant Cutaneous Oncology
- Section Nine Educational, Organizational, and Research Efforts in Transplant Dermatology
- Index
Summary
INTRODUCTION
A wealth of information has been published in recent years concerning the incidence, clinicopathological spectrum, treatment, prognosis, and prevention of skin malignancies in organ transplant recipients (OTRs). However, relatively little has been reported in relation to benign skin tumors. This section will review the available published literature, together with unpublished data, relating to benign tumors observed in our own cohort of over 800 renal transplant recipients under long-term surveillance since 1989 at Bart's and the London NHS Trust, London, U.K (BLT). It should be emphasised that accurate prevalence data are limited for almost all of these tumors, and most published and unpublished observations should therefore be regarded as essentially anecdotal until further data are available from larger cohort studies. Nonetheless, an appreciation of the spectrum of benign tumors in OTRs is important, as some of these tumors may simulate more aggressive malignancies; others represent a source of considerable morbidity, and a few may possess potential for malignant transformation. Relevant published data are summarized in Table 17.1, and particular tumors are discussed in more detail in the following text.
KERATINOCYTE TUMORS
Squamous cell papillomas, verrucal keratoses
Viral warts (HPV-induced squamous cell papillomas) are, undoubtedly, the most prevalent benign keratinocyte tumor in OTRs, and these are dealt with elsewhere in the volume. However, another group of squamous cell papillomas that lack typical HPV-associated histopathological features are also well recognised in OTRs. Often referred to as verrucal keratoses, these lesions usually present as hyperkeratotic papules and nodules (Figure 17.1).
- Type
- Chapter
- Information
- Skin Disease in Organ Transplantation , pp. 122 - 127Publisher: Cambridge University PressPrint publication year: 2008