Dermatological conditions of the female genitalia

Leith A. Banney; Jane C. Sterling

doi:10.1017/CBO9780511527036.036

35 - Dermatological conditions of the female genitalia

from Part III - Management of specific disorders

Published online by Cambridge University Press: 04 May 2010

Leith A. Banney and

Edited by

Jane MacDougall and

Leith A. Banney: Affiliation:
Department of Dermatology, Addenbrooke's Hospital, Cambridge, UK
Jane C. Sterling: Affiliation:
Reproductive Medicine Unit, University College London Hospitals, London, UK
Adam H. Balen: Affiliation:
Leeds Teaching Hospitals, University Trust
Sarah M. Creighton: Affiliation:
University College London Hospitals
Melanie C. Davies: Affiliation:
University College London
Jane MacDougall: Affiliation:
Addenbrooke's Hospital, Cambridge
Richard Stanhope: Affiliation:
Great Ormond Street Hospital

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Summary

Introduction

Disorders of the skin in the vulval area can present at any stage of life. A young child may be unable to describe changes in skin sensation and a pubertal child may not be sure what is normal and what is abnormal at a time when so many bodily changes are occurring. Vulval disease in children and adolescents may, therefore, present late and hence be diagnosed slowly. There may be misconceptions that vulval disease is a result of poor hygiene and hence a feeling of shame or embarrassment, which can result in a further delay to presentation. The causes are multiple (Table 35.1).

As in adults, the most common symptoms of vulval disease are itch and pain. In children, these may mainly be noticed by parents as a change in behaviour, for instance a reluctance to go to the toilet, as that produces pain, a wish for certain clothes that do not press on the vulval skin, or rubbing and scratching. Careful examination of the vulval skin, the vagina, where possible, the oral mucosa and the rest of the skin and appendages can give many clues to the possible diagnosis of vulval skin disease. Common and some rare causes of vulval symptoms are listed in Table 35.2 and the signs of vulval disease shown in Table 35.3.

Infections

Streptococcal infection

Definition, epidemiology and aetiology

Streptococcal infection of the vulval area is not uncommon and can present at any age, but most commonly prepubertally (Dhar et al., 1993).

Type: Chapter
Information: Paediatric and Adolescent Gynaecology
A Multidisciplinary Approach
, pp. 444 - 472

DOI: https://doi.org/10.1017/CBO9780511527036.036 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2004

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References

Adeyemi-Doro, F A B, Osoba, A O, Junaid, T A (1979). Perigenital cutaneous schistosomiasis. Br J Vener Dis 55, 446–449Google Scholar PubMed

Albers, S E, Taylor, G, Huyer, D, Oliver, G, Krafchik, B R (2000). Vulvitis circumscripta plasmacellularis mimicking child abuse. J Am Acad Dermatol 42, 1078–1080CrossRef Google Scholar PubMed

Allen, A L, Siegfried, E C (1998). The natural history of condylomata in children. J Am Acad Dermatol 39, 951–955CrossRef Google Scholar PubMed

Altchek, A (1981). Vulvovaginitis, vulval skin disease, and pelvic inflammatory disease. Pediatr Clin North Am 28, 397–431CrossRef Google Scholar PubMed

Amiry, S A, Pride, H B, Tyler, W B (2001). Perianal pseudoverrucose papules and nodules mimicking condylomata acuminata and child sexual abuse. Cutis 67, 335–338Google Scholar PubMed

Amstey, M S, Trombetta, G C (1985). Laser therapy for vulvar molluscum contagiosum infection. Am J Obstet Gynecol 153, 800–801CrossRef Google Scholar PubMed

Armstrong, D K B, Bingham, E A, Dinsmore, W W, Swann, A, Handley, J M (1998). Anogenital warts in prepubertal children: a follow-up study. Br J Dermatol 138, 544–564CrossRef Google Scholar PubMed

Atherton D J (2000). Epidermolysis Bullosa. In Textbook of Pediatric Dermatology, Harper J, Oranje A, Prose N, eds., pp 1075–1100. Blackwell Science, Oxford

Baggish, M S, Sze, E H, Johnson, R (1997). Urinary oxalate excretion and its role in vulvar pain syndrome. Am J Obstet Gynecol 177, 507–511CrossRef Google Scholar PubMed

Bargman, H (letter); Schachner, L, Hankin, D (reply) (1986). Is genital molluscum contagiosum a cutaneous manifestation of sexual abuse in children?J Am Acad Dermatol 14, 847–849CrossRef Google Scholar PubMed

Bauer, A, Geier, J, Elsner, P (2000). Allergic contact dermatitis in patients with anogenital complaints. J Reprod Med 45, 649–654Google Scholar PubMed

Berlin, C (1965). The pathogenesis of the so-called ulcus vulvae acutum. Acta Dermatol Venereol 45, 221–222Google Scholar PubMed

Bluestein, J, Furner, B B, Phillips, D (1990). Granuloma gluteale infantum: case report and review of the literature. Pediatr Dermatol 7, 196–198CrossRef Google Scholar PubMed

Boer, J, Weltevreden, E F (1996). Hidradenitis suppuritiva or acne inversa. A clinicopathological study of early lesions. Br J Dermatol 135, 721–725CrossRef Google Scholar PubMed

Bracco, G L, Carli, P, Sonni, L, Maestrini, G, Marco, A, Taddei, G L, Cattaneo, A, (1993). Clinical and histological effects of topical treatments of vulvar lichen sclerosus. J Reprod Med 38, 37–40Google Scholar

Brown, C F, Gallup, D G, Brown, V M (1988). Hidradenitis suppuritiva of the anogenital region: response to isotretinoin. Am J Obstet Gynecol 158, 12–15CrossRef Google Scholar

Burge, S M (1992). Darier's disease: the clinical features and pathogenesis. Clin Exp Dermatol 19, 193–205CrossRef Google Scholar

Chari, S P, Connolly, P, Shafi, M I, Luesley, D M (1994). The treatment of lichen sclerosus et atrophicus and squamous cell hyperplasia with graduated topical steroids. J Obstet Gynecol 14, 172–174CrossRef Google Scholar

Christian, M M, Moy, R L (1999). Treatment of Hailey—Hailey disease using short pulsed and short dwell time carbon dioxide lasers. Dermatol Surg 25, 661–663CrossRef Google Scholar PubMed

Cohen, B A, Honog, P, Androphy, E (1990). Anogenital warts in children. Clinical and virological evaluation for sexual abuse. Acta Dermatol 126, 1575–1580Google Scholar

Collier, P M, Wojnarowska, F (1992). MHC class I and II antigens in linear IgA dermatosis. J Invest Dermatol 98, 526Google Scholar

*Collier, P M, Wojnarowska, F (1993). Linear IgA disease and chronic bullous disease of childhood. Eur J Dermatol 3, 623–634Google Scholar

Collier P M, Wojnarowska F (2000). Chronic bullous disease of childhood. In Textbook of Pediatric Dermatology, Harper J, Oranje A, Prose N, eds., pp. 711–723. Blackwell Science, Oxford

Connelly, M G, Winkleman, R K (1985). Coexistence of lichen sclerosus, morphoea and lichen planus. Report of 4 cases and review of the literature. J Am Acad Dermatol 12, 844–851CrossRef Google Scholar

*Cox, R A (1997). Haemophilus influenzae: an underrated cause of vulvovaginitis in young girls. J Clin Pathol 50, 765–768CrossRef Google Scholar PubMed

DeCastro, P, Jorizzo, J, Rajaraman, S, Solomon, A R Jr, Briggaman, R A, Raimer, S S (1985). Localized vulvar pemphigoid in a child. Paediatr Dermatol 2, 302–307CrossRef Google Scholar

Dhar, V, Roker, K, Adhmi, Z, McKenzie, S (1993). Streptococcal vulvovaginitis in girls. Pediatr Dermatol 10, 366–367CrossRef Google Scholar PubMed

Donald, F E, Slack, R C B, Colman, G (1991). Streptococcus pyogenes vulvovaginitis in children in Nottingham. Epidemiol Infect 106, 459–465CrossRef Google Scholar PubMed

Eady R A J (1998). Epidermolysis Bullosa. In Textbook of Dermatology, 6th edn, Champion R H, Burton J L, Burns D A, Breathnach S M, eds., pp. 1817–1844. Blackwell Science, Oxford

Edwards, L (1989). Vulval lichen planus. Arch Dermatol 125, 1677–1680CrossRef Google Scholar

Epstein, E (1989). Cantharidin treatment of molluscum contagiosum. Acta Derm Venereol 69, 91–92Google Scholar PubMed

Escallier, F, Gaudard, S, Boulitrop-Morvan, C et al. (1991). Pemphigus superficiel de l'enfant. Ann Dermatol Venereol 118, 381–384Google Scholar

Farber, E M, Jacobs, A H (1997). Infantile psoriasis. Am J Dis Child 131, 1266–1269Google Scholar

Farber, E M, Nall, M L (1974). The natural history of psoriasis in 5600 patients. Dermatologica 148, 1–18CrossRef Google Scholar

Farrell, A M, Kirtschig, G, Dalziel, K L et al. (1999). Childhood vulval pemphigoid: a clinical and immunopathological study of five patients. Br J Dermatol 140, 308–312CrossRef Google Scholar PubMed

Feldman, R, Misouyé, I, Chavaz, R, Saurat, J H (1992). Fox—Fordyce disease: successful treatment with topical clindamycin in alcoholic propylene glycol solution. Dermatology, 184, 310–313CrossRef Google Scholar

*Fischer, G, Rogers, M (1997). Treatment of childhood vulvar lichen sclerosus with potent topical corticosteroids. Pediatr Dermatol 14, 235–238CrossRef Google Scholar

*Fischer, G, Rogers, M (2000). Vulvar disease in children: a clinical audit of 130 cases. Pediatric Dermatol 17, 1–6CrossRef Google Scholar PubMed

Fischer, G, Spurrett, B, Fischer, A (1995). The chronically symptomatic vulva. Aetiology and management. Br J Obstet Gynaecol 102, 773–779CrossRef Google Scholar PubMed

Fivozinsky, K B, Laufer, M R (1998). Vulvar disorders in prepubertal girls. A literature review. J Reprod Med 43, 763–773Google Scholar PubMed

Franco, I (2000). Oral cimetidine for the management of genital and perigenital warts in children. J Urol 164, 1074–1075CrossRef Google Scholar PubMed

Friedman, M, Gal, D (1987). Keloid scars as a result of CO2 laser for molluscum contagiosum. Obstet Gynecol 70, 394–396Google Scholar PubMed

Fujiwara, H, Fujiwara, K, Hashimoto, K et al. (1997). Detection of Borrelia burgdorferi (B. garnii or B. afzelii) DNA in morphoea and lichen sclerosus et atrophicus tissues of German and Japanese but not of US patients. Arch Dermatol 133, 41–44CrossRef Google Scholar

Giacobetti, R, Caro, W A, Roenigk, H H (1979). Fox—Fordyce disease: control with tretinoin cream. Arch Dermatol 115, 1365–1366CrossRef Google Scholar PubMed

Giaquinto, C, Del Mistro, A, Rossi, A et al. (2000). Vulval carcinoma in a 12-year-old girl with vertically acquired human immunodeficiency virus infection. Pediatrics 106, e57CrossRef Google Scholar

Goldberg, N S, Esterly, N B, Rothman, K F (1992). Perianal pseudoverrucous papules and nodules in children. Arch Dermatol 128, 240–242CrossRef Google Scholar PubMed

Gryngarten, M G, Turco, M D, Escobar, M E, Woloj, M G, Bergada, C (1994). Shigella vulvovaginitis in prepubertal girls. Pediatr Gynecol 7, 86–89Google Scholar

Guenther, L, Shum, D (1990). Localized childhood vulvar pemphigoid. J Am Acad Dermatol 22, 762–764CrossRef Google Scholar PubMed

Halasz, C, Silvers, D, Crum, C P (1986). Bowenoid papulosis in a three year old girl. J Am Acad Dermatol 14, 326–330CrossRef Google Scholar

Handley, J, Hanks, E, Armstrong, K et al. (1997). Common association of HPV 2 with anogenital warts in prepubertal children. Pediatric Dermatol 14, 339–343CrossRef Google Scholar PubMed

Hart, W R, Norris, H J, Helwig, E B (1975). Relation of lichen sclerosus et atrophicus of the vulva to the development of carcinoma. Obstet Gynecol 45, 369–377Google Scholar PubMed

Haustein, U F (1988). Localized nonscarring bullous pemphigoid of the vagina. Dermatologica 176, 200–201CrossRef Google Scholar PubMed

Heller, R H, Joseph, J M, Davis, H J (1969). Vulvovaginitis in the premenarcheal child. J Pediatr 74, 370–377CrossRef Google Scholar PubMed

Henk Sillevis Smitt J (2000). Pemphigus, pemphigoid and epidermolysis bullosa acquisita. In Textbook of Pediatric Dermatology, Harper J, Oranje A, Prose N, eds., pp 731–753. Blackwell Science, Oxford

Hervonen, K, Karell, K, Holopainen, P, Collin, P, Partanen, J, Reunala, T (2000). Concordance of dermatitis herpetiformis and celiac disease in monozygous twins. J Invest Dermatol 115, 990–993CrossRef Google Scholar PubMed

Holden C A, Parish W E (1998). Atopic dermatitis. In Textbook of Dermatology, 6th edn, Champion R H, Burton J L, Burns D A, Breathnach S M, eds., pp. 681–708. Blackwell Science, Oxford

Hudson, L B, Perlman, S E (1998). Necrotising genital ulcerations in a pre-menarcheal female with mononucleosis. Obstet Gynecol 92, 642–644Google Scholar

Kawasaki, T (1995). Kawasaki disease. Acta Pediatr 84, 713–715CrossRef Google Scholar PubMed

Kingston, M, Warren, C, Carlin, E (2001). Tropical warts. Lancet 358, 808CrossRef Google Scholar PubMed

Klaus, S, Shvil, Y, Mumcuoglu, K Y (1994). Generalised infection of a 3 1/2 year old girl with the pubic louse. Pediatr Dermatol 11, 26–28CrossRef Google Scholar

Kokx, N P, Comstock, J A, Facklam, R R (1987). Streptococcal perianal disease in children. Pediatrics 80, 659–663Google Scholar PubMed

Konya, J, Gow, E (1996). Granuloma gluteale infantum. Aust J Dermatol 37, 57–58CrossRef Google Scholar PubMed

Koumantakis, E E, Hassan, E A, Deligeoroglou, E K, Creatsas, G K (1997). Vulvovaginitis during childhood and adolescence. J Pediatr Adolesc Gynecol 10, 39–43CrossRef Google Scholar PubMed

Kronthal, H L, Pomeranz, J R, Sitomer, G (1965). Fox—Fordyce disease. Arch Dermatol 91, 243–245CrossRef Google Scholar PubMed

Lambiris, A, Greaves, M W (1997). Dyspareunia and vulvodynia: unrecognised manifestations of symptomatic dermographism. Lancet 349, 28Google Scholar PubMed

Lafferty, W E, Coombs, R W, Benedetti, J, Critchlow, C, Corey, L (1987). Recurrences after oral and genital herpes simplex virus infection. N Engl J Med 316, 1444–1449CrossRef Google Scholar PubMed

Leigh, G, Marsden, R, Wojnarowska, F (1988). Linear IgA dermatosis with severe arthralgia. Br J Dermatol 119, 789–792CrossRef Google Scholar PubMed

Lemon, M A, Weston, W L, Huff, J C (1997). Childhood paraneoplastic pemphigus associated with Castleman's tumour. Br J Dermatol 136, 115–117CrossRef Google Scholar PubMed

Leonard J N (2000). Dermatitis herpetiformis. In Textbook of Pediatric Dermatology, Harper J, Oranje A, Prose N, eds., pp. 724–730. Blackwell Science, Oxford

Leutscher, P, Ravaoalimalala, V E, Raharisolo, C et al. (1998). Clinical findings in female genital schistosomiasis in Madagascar. Trop Med Int Health 3, 327–332CrossRef Google Scholar PubMed

Lewis, F, Messenger, A G, Wales, J K (1993). Hidradenitis suppuritiva as a presenting feature of premature adrenarche. Br J Dermatol 129, 447–448CrossRef Google Scholar

Lewis, H M, Renaula, T L, Garioch, J J et al. (1996). Protective effect of a gluten free diet against development of lymphoma in dermatitis herpetiformis. Br J Dermatol 135, 363–367CrossRef Google Scholar PubMed

Lorrmann, H, Cendron, J, Bavieral, E (1985). Kystes vulvaires à révélation néonatale. A propos de 6 cas. Ann Urol 19, 259–262Google Scholar

Lynch P J, Edwards L (1994). White patches and plaques. In Genital Dermatology, Lynch P J, Edwards L, eds., pp. 149–162. Churchill-Livingstone, New York

MacFarlane, D E, Sharma, D P (1987). Haemophilus influenzae and genital tract infections in children. Acta Paediatr Scand 76, 363–364CrossRef Google Scholar PubMed

MacLean, A B (1993). Precursors of vulva cancers. Curr Obstet Gynecol 3, 149–156CrossRef Google Scholar

Marren, P, Wojnarowska, F, Powell, S (1992). Allergic contact dermatitis and vulvar dermatoses. Br J Dermatol 126, 52–56CrossRef Google Scholar PubMed

Mawad, N M, Hassanein, O M, Mahmoud, O M, Taylor, M G (1992). Schistosomal vulval granuloma in a 12 year old Sudanese girl. Trans Roy Soc Trop Med Hyg 86, 644CrossRef Google Scholar

McKay, M (1993). Dysesthetic (‘essential’) vulvodynia. Treatment with amitriptyline. J Reprod Med 38, 9–13Google Scholar

Mengesha, Y M, Holcombe, T C, Hansen, R C (1999). Prepubertal hidradenitis suppuritiva: Two case reports and review of the literature. Pediatr Dermatol 16, 292–296CrossRef Google Scholar

Meyrick Thomas, R H, Ridley, C M, McGibbon, D H, Black, M M (1998). Lichen sclerosus et atrophicus and autoimmunity: a study of 350 women. Br J Dermatol 118, 41–46CrossRef Google Scholar

Mortimer, P S, Dawber, R P R, Gales, M A, Moore, R A (1986). A double-blind controlled cross-over trial of cyproterone acetate in females with hidradenitis suppuritiva. Br J Dermatol 115, 263–268CrossRef Google Scholar

Nasr, I, Tometzki, A J P, Schofield, O M V (2000). Kawasaki disease: an update. Clin Exp Dermatol 26, 6–12CrossRef Google Scholar

Neuberger, J W, Takahashi, M, Burns, J C et al. (1986). The treatment of Kawasaki's disease with intravenous gamma globulin. N Engl J Med 315, 341–347CrossRef Google Scholar

Nevill, E A, Finn, O A (1975). Psoriasiform napkin dermatitis: a follow-up study. Br J Dermatol 92, 279–285CrossRef Google Scholar

Nogita, T, Kawabata, Y, Tsuchida, T et al. (1990). Clitoral and labial involvement of neurofibromatosis. J Am Acad Dermatol 5, 937–938CrossRef Google Scholar

Ohkuma, M (1990). Molluscum contagiosum treated with iodine solution and salicylic acid plaster. Int J Dermatol 29, 443–445CrossRef Google Scholar PubMed

Padel, A F, Venning, V A, Evans, M F, Quantrill, H M, Fleming, K A (1990). Human papillomavirus in anogenital warts in children. Br Med J 300, 1491–1494CrossRef Google Scholar PubMed

Paek, S C, Merritt, D F, Mallory, S B (2001). Pruritus vulvae in prepubertal children. J Am Acad Dermatol 44, 795–802CrossRef Google Scholar PubMed

Palmer, R A, Keefe, M (2001). Early-onset hidradenitis suppuritiva. Clin Exp Dermatol 26, 501–503CrossRef Google Scholar

Papa, C M, Berger, R S (1976). Venereal herpes-like molluscum contagiosum: treatment with tretinoin. Cutis 18, 537–540Google Scholar PubMed

Patterson, J A KAckerman, A B (1984). Lichen sclerosus et atrophicus is not related to morphoea. Am J Dermatopathol 6, 323–335CrossRef Google Scholar PubMed

Pelisse, M (1989). The vulvo-vaginal—gingival syndrome: a new form of erosive lichen planus. Int J Dermatol 28, 381–384CrossRef Google Scholar PubMed

Peters, M S, McEvoy, M T (1989). IgA antiendomysial antibodies in dermatitis herpetiformis. J Am Acad Dermatol 21, 1225–1231CrossRef Google Scholar PubMed

Petersen, C S, Brocks, K, Weisman, K, Kobayasi, T, Thompsen, H K (1996). Pretibial epidermolysis bullosa with vulvar involvement. Acta Dermatovenereol 76, 80–81Google Scholar PubMed

*Piippo, S, Lenko, H, Vuento, R (2000). Vulval symptoms in paediatric and adolescent patients. Acta Paediatr 89, 431–435CrossRef Google Scholar

Pinkus, H (1973). Treatment of Fox—Fordyce disease. J Am Med Assoc 223, 924CrossRef Google Scholar PubMed

Pincus S H, McKay M (1993). Lichen sclerosus et atrophicus. In Dermatology in General Medicine, 4th edn, Fitzpatrick T B, Eisen A Z, Wolff K, Freedberg I M, Austen, K F, eds., pp. 1469–1470. McGraw-Hill, New York

Pokorny, F (1994). Long-term intravaginal presence of foreign bodies in children. A preliminary study. J Reprod Med 39, 931–935Google Scholar PubMed

Powell, J, Wojnarowska, F (2001). Childhood vulval lichen sclerosus: an increasingly common problem. J Am Acad Dermatol 44, 803–806CrossRef Google Scholar

Powell, J, Wojnarowska, F, Winsey, S, Marren, P, Welsh, K (2000). Lichen sclerosus premenarche: autoimmunity and immunogenetics. Br J Dermatol 142, 481–484CrossRef Google Scholar PubMed

Powell, J, Wojnarowska, F, Shafi, M, Laird, E (2001). Childhood-onset lichen sclerosus and vulval squamous cell carcinoma. Br J Dermatol 145(Suppl. 59), 124–125CrossRef Google Scholar

Rakover, Y, Adar, H, Tal, I, Lang, Y, Kedar, A (1987). Behçet disease: long term follow-up of three children and review of literature. Pediatrics 83, 986–992Google Scholar

Rasmussen, H B, Hagdrup, H, Schmidt, H (1986). Psoriasiform napkin dermatitis. Acta Derm Venereol 66, 534–536Google Scholar

Reid, R, Omoto, K H, Precop, S L et al. (1995). Flashlamp-excited dye laser therapy of idiopathic vulvodynia is safe and efficaceous. Am J Obstet Gynecol 172, 1684–1701CrossRef Google Scholar

Reunala, T, Kosnai, L, Karpati, S, Kuitunen, P, Torok, E, Savilahti, E (1984). Dermatitis herpetiformis: jejunal findings and skin response to gluten free diet. Arch Dis Child 59, 517–522CrossRef Google Scholar PubMed

Ridley C M (1988). General dermatological conditions and dermatoses of the vulva. In The Vulva, Ridley C M, ed., p. 138. Churchill Livingstone, Edinburgh

Ridley, C M (1989). Lichen sclerosus et atrophicus. Semin Dermatol 8, 54-63Google Scholar PubMed

Robinson, J B, Im, D D, Simmons-O'Brian, E, Rosenshein, N B (1998). Etretinate: therapy for plasma cell vulvitis. Obstet Gynecol 92, 706Google Scholar PubMed

Rosdahl, I, Edmar, B, Gisslen, H, Nordin, P, Lillieborg, S (1988). Curettage of molluscum contagiosum in children: analgesia by topical application of a lidocaine/prilocaine cream (EMLA). Acta Derm Venereol 68, 149–153Google Scholar

Rowell N R, Goodfield M J D (1998). Lichen sclerosus. In Textbook of Dermatology, 6th edn, Champion R H, Burton J L, Burns D A, Breathnach S M, eds., pp. 2547–2553. Blackwell Science, Oxford

Rybojad, M, Leblanc, T, Flageul, B et al. (1993). Paraneoplastic pemphigus in a child with a T-cell lymphoblastic lymphoma. Br J Dermatol 128, 418–422CrossRef Google Scholar

Salopek, T G, Krol, A, Jimbow, K (1993). Case report of Darier's disease localised to the vulva in a 5 year old girl. Pediatr Dermatol 10, 146–148CrossRef Google Scholar

Samman, P D (1961). Lichen planus: an analysis of 200 cases. Trans Rep St John's Hosp Dermatol Soc, 46, 36–38Google Scholar PubMed

Scherbenske, J M, Lupton, G P, James, W D, Kirkle, D B (1988). Vulval syringomas occurring in a 9 year old child. J Am Acad Dermatol 19, 575–577CrossRef Google Scholar

Scurry, J, Dennerstein, G, Brenan, J, Ostor, A, Mason, G, Dorevitch, A (1993). Vulvitis circumscripta plasmacellularis. A clinicopathological entity?J Reprod Med 38, 14–18Google Scholar

Sellman, S P, Hupertz, V F, Reece, R M (1996). Crohn's disease presenting as suspected abuse. Pediatrics 97, 272–274Google Scholar PubMed

Silverberg, N B, Laude, T A (1998). Jacquet diaper dermatitis: a diagnosis of etiology. Pediatr Dermatol 15, 489CrossRef Google Scholar PubMed

Sinha, P, Sorinola, O, Luesley, D M (1999). Lichen sclerosus of the vulva. Long term steroid maintenance therapy. J Reprod Med 44, 621–624Google Scholar PubMed

Sisson, B A, Glick, L (1998). Genital ulceration as a presenting manifestation of infectious mononucleosis. J Pediatr Adolesc Gynecol 11, 185–187CrossRef Google Scholar PubMed

Steinkampf, M P, Reilly, S D, Ackerman, A B (1987). Vaginal agglutination and hematometra associated with epidermolysis bullosa. Obstet Gynecol 69, 519–521Google Scholar PubMed

Storer, J, Galen, W K, Nesbitt, L T, DeLeo, V A (1982). Neonatal pemphigus vulgaris. J Am Acad Dermatol 6, 929–932CrossRef Google Scholar PubMed

Stratakis, C A, Graham, W, DiPalma, J, Leiowitz, I (1994). Misdiagnosis of perianal manifestations of Crohn's disease. Two cases and a review of the literature. Clin Pediatr 33, 631–633CrossRef Google Scholar

Syed, T A, Lundin, S, Ahmad, M (1994). Topical 0.3% and 0.5% podophyllotoxin cream for self-treatment of molluscum contagiosum in males. Dermatology 189, 65–68CrossRef Google Scholar PubMed

Tappeiner, S, Pfleger, L (1971). Granuloma gluteale infantum. Hautartz 22, 383–388Google Scholar PubMed

Terpstra, H, Jong, M C J M, Klokke, A H (1979). In vivo bound pemphigus antibodies in a still born infant. Arch Dermatol 115, 316–319CrossRef Google Scholar

Tkach, J R (1979). Tretinoin treatment of Fox—Fordyce disease. Arch Dermatol 15, 1285CrossRef Google Scholar

Tuffnell, D, Buchan, P C (1991). Crohn's disease of the vulva in childhood. Br J Clin Pract 45, 159–160Google Scholar PubMed

Uziel, Y, Brik, R, Padeh, S et al. (1998). Juvenile Behçet's disease in Israel. The Pediatric Rheumatology Study Group of Israel. Clin Exp Rheumatol 16, 502–505Google Scholar

der Werth, J M, Williams, H C, Raeburn, J A (2000). The clinical genetics of hidradenitis suppuritiva revisited. Br J Dermatol 142, 947–953CrossRef Google Scholar

Warin, R P, Faulkner, K E (1961). Napkin psoriasis. Br J Dermatol 73, 445–450CrossRef Google Scholar PubMed

Weitzner, J M, Fields, K W, Robinson, M J (1989). Pediatric Bowenoid papulosis: risks and management. Pediatr Dermatol 6, 303–305CrossRef Google Scholar PubMed

Werlin, S L, Esterly, N B, Oechler, H (1992). Crohn's disease presenting as unilateral labial hypertrophy. J Am Acad Dermatol 27, 893–895CrossRef Google Scholar PubMed

White, G, Jantos, M, Glazer, H (1997). Establishing the diagnosis of vulvar vestibulitis. J Reprod Med 42, 157–160Google Scholar

Wilson, R W (1993). Genital ulcers and mononucleosis. Pediatr Infect Dis J 12, 418CrossRef Google Scholar PubMed

Wojnarowska, F, Marsden, R, Bhogal, B, Black, M (1988). Chronic bullous disease of childhood, childhood cicatricial pemphigoid and linear IgA disease of adults, a comparative study demonstrating clinical and immunopathological overlap. J Am Acad Dermatol 19, 792–805CrossRef Google Scholar

Wood, P L, Bevan, T (1999). Child sexual abuse enquiries and unrecognised vulval lichen sclerosus et atrophicus. Br Med J 319, 899–900CrossRef Google Scholar PubMed

Yilmaz, E, Alpsoy, E, Basaran, E (1995). Cimetidine therapy for warts: a placebo-controlled, double-blind study. J Am Acad Dermatol 34, 1005–1007CrossRef Google Scholar

Yoganathan, S, Bohl, T G, Mason, G (1994). Plasma cell balanitis and vulvitis (of Zoon). J Reprod Med 39, 939–944Google Scholar

Yu, C C, Cook, M G (1990). Hidradenitis suppuritiva: a disease of follicular epithelium rather than apocrine glands. Br J Dermatol 122, 763–769CrossRef Google Scholar

Zeiguer, N J, Galvano, A, Comparato, M R, Guelfand, L, Benitez, M (1992). Vulvar abscesses caused by streptococcus pneumonia. Pediatr Infect Dis J 11, 335–336CrossRef Google Scholar

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