In Chapter 2, we will show how you can use the core message to build and structure the major parts of your presentation. The core building blocks of introduction, method, results, discussion, and conclusion can be found in the vast majority of presentations, regardless of whether you are presenting a laboratory experiment, a clinical trial, or a literature study. In this chapter, we will discuss each of these building blocks at some length, and show you how you can use your core message to decide what to tell and what not to tell your audience. We will also show you some ways to make shortcuts in your presentation in case you are under time pressure.