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Chapter 16 - Perioperative Neurocognitive Disorder Mitigation Strategies

from Section 4 - Clinical Recommendations and Prevention

Published online by Cambridge University Press:  11 April 2019

Roderic G. Eckenhoff
Affiliation:
University of Pennsylvania
Niccolò Terrando
Affiliation:
Duke University, North Carolina
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Publisher: Cambridge University Press
Print publication year: 2019

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References

Mason, SE, Noel-Storr, A, Ritchie, CW. The impact of general and regional anesthesia on the incidence of post-operative cognitive dysfunction and post-operative delirium: a systematic review with meta-analysis. J Alzheimers Dis 2010; 22 Suppl 3: 6779Google Scholar
Guay, J. General anaesthesia does not contribute to long-term post-operative cognitive dysfunction in adults: a meta-analysis. Ind J Anaesth 2011; 55: 358–63Google Scholar
Silbert, BS, Evered, LA, Scott, DA. Incidence of postoperative cognitive dysfunction after general or spinal anaesthesia for extracorporeal shock wave lithotripsy. Br J Anaesth 2014; 113: 784–91Google Scholar
Sieber, FE, Zakriya, KJ, Gottschalk, A, et al. Sedation depth during spinal anesthesia and the development of postoperative delirium in elderly patients undergoing hip fracture repair. Mayo Clin Proc 2010; 85: 1826Google Scholar
Iwasaki, M, Edmondson, M, Sakamoto, A, Ma, D. Anesthesia, surgical stress, and “long-term” outcomes. Acta Anaesthesiol Taiwan 2015; 53: 99104Google Scholar
Liang, G, Ward, C, Peng, J, Zhao, Y, Huang, B, Wei, H. Isoflurane causes greater neurodegeneration than an equivalent exposure of sevoflurane in the developing brain of neonatal mice. Anesthesiology 2010; 112: 1325–34Google Scholar
Dong, Y, Zhang, G, Zhang, B, et al. The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels. Arch Neurol 2009; 66: 620–31Google Scholar
Eger, EI 2nd. Characteristics of anesthetic agents used for induction and maintenance of general anesthesia. Am J Health Syst Pharm 2004; 61 Suppl 4: S3–10Google Scholar
Geng, YJ, Wu, QH, Zhang, RQ. Effect of propofol, sevoflurane, and isoflurane on postoperative cognitive dysfunction following laparoscopic cholecystectomy in elderly patients: a randomized controlled trial. J Clin Anesth 2017; 38: 165–71Google Scholar
Royse, CF, Andrews, DT, Newman, SN, et al. The influence of propofol or desflurane on postoperative cognitive dysfunction in patients undergoing coronary artery bypass surgery. Anaesthesia 2011; 66: 455–64Google Scholar
Liu, SS, Strodtbeck, WM, Richman, JM, Wu, CL. A comparison of regional versus general anesthesia for ambulatory anesthesia: a meta-analysis of randomized controlled trials. Anesth Analg 2005; 101: 1634–42Google Scholar
Le Freche, H, Brouillette, J, Fernandez-Gomez, FJ, et al. Tau phosphorylation and sevoflurane anesthesia: an association to postoperative cognitive impairment. Anesthesiology 2012; 116: 779–87Google Scholar
Tang, JX, Mardini, F, Janik, LS, et al. Modulation of murine Alzheimer pathogenesis and behavior by surgery. Ann Surg 2013; 257: 439–48Google Scholar
Mardini, F, Tang, JX, Li, JC, Arroliga, MJ, Eckenhoff, RG, Eckenhoff, MF. Effects of propofol and surgery on neuropathology and cognition in the 3xTgAD Alzheimer transgenic mouse model. Br J Anaesth 2017; 119: 472–80Google Scholar
Zurek, AA, Yu, J, Wang, DS, et al. Sustained increase in alpha5GABAA receptor function impairs memory after anesthesia. J Clin Invest 2014; 124: 5437–41Google Scholar
Ballard, C, Jones, E, Gauge, N, et al. Optimised anaesthesia to reduce post operative cognitive decline (POCD) in older patients undergoing elective surgery, a randomised controlled trial. PLoS One 2012; 7: e37410Google Scholar
Deiner, S, Luo, X, Silverstein, JH, Sano, M. Can intraoperative processed EEG predict postoperative cognitive dysfunction in the elderly? Clin Ther 2015; 37: 2700–5Google Scholar
Rasmussen, LS, Steentoft, A, Rasmussen, H, Kristensen, PA, Moller, JT. Benzodiazepines and postoperative cognitive dysfunction in the elderly. ISPOCD Group. International Study of Postoperative Cognitive Dysfunction. Br J Anaesth 1999; 83: 585–9Google Scholar
van den Boogaard, M, Slooter, AJC, Bruggemann, RJM, et al. Effect of haloperidol on survival among critically ill adults with a high risk of delirium: the REDUCE randomized clinical trial. JAMA 2018; 319: 680–90Google Scholar
Pisani, MA, Araujo, KL, Murphy, TE. Association of cumulative dose of haloperidol with next-day delirium in older medical ICU patients. Crit Care Med 2015; 43: 9961002Google Scholar
American Geriatrics Society 2015 Updated Beers criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc 2015; 63: 2227–46Google Scholar
Banks, WA, Erickson, MA. The blood-brain barrier and immune function and dysfunction. Neurobiol Dis 2010; 37: 2632Google Scholar
Serrats, J, Schiltz, JC, Garcia-Bueno, B, van Rooijen, N, Reyes, TM, Sawchenko, PE. Dual roles for perivascular macrophages in immune-to-brain signaling. Neuron 2010; 65: 94106Google Scholar
Rea, K, Dinan, TG, Cryan, JF. The microbiome: a key regulator of stress and neuroinflammation. Neurobiol Stress 2016; 4: 2333Google Scholar
Penkowa, M, Moos, T, Carrasco, J, et al. Strongly compromised inflammatory response to brain injury in interleukin-6-deficient mice. Glia 1999; 25: 343–57Google Scholar
Chan, JK, Glass, GE, Ersek, A, et al. Low-dose TNF augments fracture healing in normal and osteoporotic bone by up-regulating the innate immune response. EMBO Mol Med 2015; 7: 547–61Google Scholar
Terrando, N, Gomez-Galan, M, Yang, T, et al. Aspirin-triggered resolvin D1 prevents surgery-induced cognitive decline. FASEB J 2013; 27: 3564–71Google Scholar
Terrando, N, Eriksson, LI, Ryu, JK, et al. Resolving postoperative neuroinflammation and cognitive decline. Ann Neurol 2011; 70: 986–95Google Scholar
Kamer, AR, Galoyan, SM, Haile, M, et al. Meloxicam improves object recognition memory and modulates glial activation after splenectomy in mice. Eur J Anaesthesiol 2012; 29: 332–7Google Scholar
Mu, DL, Zhang, DZ, Wang, DX, et al. Parecoxib supplementation to morphine analgesia decreases incidence of delirium in elderly patients after hip or knee replacement surgery: a randomized controlled trial. Anesth Analg 2017; 124: 19922000Google Scholar
Ottens, TH, Dieleman, JM, Sauer, AM, et al. Effects of dexamethasone on cognitive decline after cardiac surgery: a randomized clinical trial. Anesthesiology 2014; 121: 492500Google Scholar
Valentin, LS, Pereira, VF, Pietrobon, RS, et al. Effects of single low dose of dexamethasone before noncardiac and nonneurologic surgery and general anesthesia on postoperative cognitive dysfunction – a phase III double blind, randomized clinical trial. PLoS One 2016; 11: e0152308Google Scholar
Fang, Q, Qian, X, An, J, Wen, H, Cope, DK, Williams, JP. Higher dose dexamethasone increases early postoperative cognitive dysfunction. J Neurosurg Anesthesiol 2014; 26: 220–5Google Scholar
Lin, D, Cao, L, Wang, Z, Li, J, Washington, JM, Zuo, Z. Lidocaine attenuates cognitive impairment after isoflurane anesthesia in old rats. Behav Brain Res 2012; 228: 319–27Google Scholar
Chen, RM, Chen, TG, Chen, TL, et al. Anti-inflammatory and antioxidative effects of propofol on lipopolysaccharide-activated macrophages. Ann N Y Acad Sci 2005; 1042: 262–71Google Scholar
Cruz, FF, Rocco, PR, Pelosi, P. Anti-inflammatory properties of anesthetic agents. Crit Care 2017; 21: 67Google Scholar
Xu, D, Yang, W, Zhao, G. Effect of propofol and inhalation anesthesia on postoperative cognitive dysfunction in the elderly: a meta-analysis. Nan Fang Yi Ke Da Xue Xue Bao 2012; 32: 1623–7Google Scholar
Hocker, J, Stapelfeldt, C, Leiendecker, J, et al. Postoperative neurocognitive dysfunction in elderly patients after xenon versus propofol anesthesia for major noncardiac surgery: a double-blinded randomized controlled pilot study. Anesthesiology 2009; 110: 1068–76Google Scholar
Batistaki, C, Riga, M, Zafeiropoulou, F, Lyrakos, G, Kostopanagiotou, G, Matsota, P. Effect of sugammadex versus neostigmine/atropine combination on postoperative cognitive dysfunction after elective surgery. Anaesth Intensive Care 2017; 45: 581–8Google Scholar
Piskin, O, Kucukosman, G, Altun, DU, et al. The effect of sugammadex on postoperative cognitive function and recovery. Braz J Anesthesiol 2016; 66: 376–82Google Scholar
Doraiswamy, PM, Babyak, MA, Hennig, T, et al. Donepezil for cognitive decline following coronary artery bypass surgery: a pilot randomized controlled trial. Psychopharmacol Bull 2007; 40: 5462Google Scholar
Marcantonio, ER, Palihnich, K, Appleton, P, Davis, RB. Pilot randomized trial of donepezil hydrochloride for delirium after hip fracture. J Am Geriatr Soc 2011; 59 Suppl 2: S282–8Google Scholar
Seitz, DP, Gill, SS, Gruneir, A, et al. Effects of cholinesterase inhibitors on postoperative outcomes of older adults with dementia undergoing hip fracture surgery. Am J Geriatr Psychiatry 2011; 19: 803–13Google Scholar
Sampson, EL, Raven, PR, Ndhlovu, PN, et al. A randomized, double-blind, placebo-controlled trial of donepezil hydrochloride (Aricept) for reducing the incidence of postoperative delirium after elective total hip replacement. Int J Geriatr Psychiatry 2007; 22: 343–9Google Scholar
Liptzin, B, Laki, A, Garb, JL, Fingeroth, R, Krushell, R. Donepezil in the prevention and treatment of post-surgical delirium. Am J Geriatr Psychiatry 2005; 13: 1100–6Google Scholar
Moller, JT, Cluitmans, P, Rasmussen, LS, et al. Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study. ISPOCD Investigators. International Study of Post-Operative Cognitive Dysfunction. The Lancet 1998; 351: 857–61Google Scholar
Schoen, J, Meyerrose, J, Paarmann, H, Heringlake, M, Hueppe, M, Berger, KU. Preoperative regional cerebral oxygen saturation is a predictor of postoperative delirium in on-pump cardiac surgery patients: a prospective observational trial. Crit Care 2011; 15: R218Google Scholar
Kim, J, Shim, JK, Song, JW, Kim, EK, Kwak, YL. Postoperative cognitive dysfunction and the change of regional cerebral oxygen saturation in elderly patients undergoing spinal surgery. Anesth Analg 2016; 123: 436–44Google Scholar
Murkin, JM, Adams, SJ, Novick, RJ, et al. Monitoring brain oxygen saturation during coronary bypass surgery: a randomized, prospective study. Anesth Analg 2007; 104: 51–8Google Scholar
Panza, GA, Taylor, BA, MacDonald, HV, et al. Can exercise improve cognitive symptoms of Alzheimer’s disease? J Am Geriatr Soc 2018; 66: 487–95Google Scholar
McEwen, SC, Siddarth, P, Abedelsater, B, et al. Simultaneous aerobic exercise and memory training program in older adults with subjective memory impairments. J Alzheimers Dis 2018; 62: 795806Google Scholar
Morris, JK, Vidoni, ED, Johnson, DK, et al. Aerobic exercise for Alzheimer’s disease: a randomized controlled pilot trial. PLoS One 2017; 12: e0170547Google Scholar
Barakat, HM, Shahin, Y, Khan, JA, McCollum, PT, Chetter, IC. Preoperative supervised exercise improves outcomes after elective abdominal aortic aneurysm repair: a randomized controlled trial. Ann Surg 2016; 264: 4753Google Scholar

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