Skip to main content Accessibility help
×
Hostname: page-component-76fb5796d-5g6vh Total loading time: 0 Render date: 2024-04-28T03:20:46.468Z Has data issue: false hasContentIssue false

Chapter 10 - Malignancies of Transplantation

Published online by Cambridge University Press:  17 March 2018

Phillip Ruiz
Affiliation:
University of Miami School of Medicine
Get access
Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2018

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Engels, EA, Pfeiffer, RM, Fraumeni, JF Jr., et al. Spectrum of Cancer Risk among US Solid Organ Transplant Recipients. JAMA: The Journal of the American Medical Association. 2011;306:1891–901.Google Scholar
Miao, Y, Everly, JJ, Gross, TG, et al. De novo Cancers Arising in Organ Transplant Recipients Are Associated with Adverse Outcomes Compared with the General Population. Transplantation. 2009;87:1347–59.CrossRefGoogle ScholarPubMed
Murray, JE, Wilson, RE, Tilney, NL, et al. Five Years’ Experience in Renal Transplantation with Immunosuppressive Drugs: Survival, Function, Complications, and the Role of Lymphocyte Depletion by Thoracic Duct Fistula. Annals of Surgery. 1968;168:416–35.CrossRefGoogle ScholarPubMed
Hanto, DW, Frizzera, G, Purtilo, DT, et al. Clinical Spectrum of Lymphoproliferative Disorders in Renal Transplant Recipients and Evidence for the Role of Epstein-Barr Virus. Cancer Res. 1981;41:4253–61.Google Scholar
Frizzera, G, Hanto, DW, Gajl-Peczalska, KJ, et al. Polymorphic Diffuse B-cell Hyperplasias and Lymphomas in Renal Transplant Recipients. Cancer Res. 1981;41:4262–79.Google Scholar
Starzl, TE, Nalesnik, MA, Porter, KA, et al. Reversibility of Lymphomas and Lymphoproliferative Lesions Developing under Cyclosporin-steroid Therapy. Lancet. 1984;1:583–7.Google Scholar
Nalesnik, MA, Jaffe, R, Starzl, TE, et al. The Pathology of Posttransplant Lymphoproliferative Disorders Occurring in the Setting of Cyclosporine A-Prednisone Immunosuppression. American Journal of Pathology. 1988;133:173–92.Google ScholarPubMed
Knowles, DM, Cesarman, E, Chadburn, A, et al. Correlative Morphologic and Molecular Genetic Analysis Demonstrates Three Distinct Categories of Posttransplantation Lymphoproliferative Disorders. Blood. 1995;85:552–65.CrossRefGoogle ScholarPubMed
Swerdlow, SH, Campo, E, Harris, NL, et al., editors. WHO Classification of Tumours of the Haematopoietic and Lymphoid Tissues. Lyon, France: IARC; 2008.Google Scholar
Dharnidharka, VR, Tejani, AH, Ho, PL, et al. Post-transplant Lymphoproliferative Disorder in the United States: Young Caucasian Males Are at Highest Risk. American Journal of Transplantation: Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2002;2:993–8.CrossRefGoogle ScholarPubMed
Clarke, CA, Morton, LM, Lynch, C, et al. Risk of Lymphoma Subtypes after Solid Organ Transplantation in the United States. British Journal of Cancer. 2013;109:280–8.Google Scholar
Dharnidharka, VR, Lamb, KE, Gregg, JA, et al. Associations between EBV Serostatus and Organ Transplant Type in PTLD Risk: An Analysis of the SRTR National Registry Data in the United States. American Journal of Transplantation: Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2012;12:976–83.Google Scholar
Manez, R, Breinig, MC, Linden, P, et al. Posttransplant Lymphoproliferative Disease in Primary Epstein-Barr Virus Infection after Liver Transplantation: The Role of Cytomegalovirus Disease. The Journal of Infectious Diseases. 1997;176:1462–7.Google Scholar
Dharnidharka, VR. Epidemiology of PTLD. In: Dharnidharka, VR, Green, M, Webber, SA, editors. Post-Transplant Lymphoproliferative Disorders: Springer; 2010. p. 1728.CrossRefGoogle Scholar
Thorley-Lawson, DA, Gross, A. Persistence of the Epstein-Barr virus and the Origins of Associated Lymphomas. The New England Journal of Medicine. 2004;350:1328–37.Google Scholar
Young, LS, Rickinson, AB. Epstein-Barr Virus: 40 Years On. Nature Reviews Cancer. 2004;4:757–68.Google Scholar
Chijioke, O, Azzi, T, Nadal, D, et al. Innate Immune Responses against Epstein Barr Virus Infection. Journal of Leukocyte Biology. 2013.Google Scholar
Aspord, C, Laurin, D, Richard, MJ, et al. Induction of Antiviral Cytotoxic T Cells by Plasmacytoid Dendritic Cells for Adoptive Immunotherapy of Posttransplant Diseases. American Journal of Transplantation: Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2011;11:2613–26.Google Scholar
Ning, RJ, Xu, XQ, Chan, KH, et al. Long-term Carriers Generate Epstein-Barr Virus (EBV)-specific CD4(+) and CD8(+) Polyfunctional T-cell Responses which Show Immunodominance Hierarchies of EBV Proteins. Immunology. 2011;134:161–71.Google Scholar
Sherritt, MA, Bharadwaj, M, Burrows, JM, et al. Reconstitution of the Latent T-Lymphocyte Response to Epstein-Barr Virus Is Coincident with Long-term Recovery from Posttransplant Lymphoma after Adoptive Immunotherapy. Transplantation. 2003;75:1556–60.CrossRefGoogle ScholarPubMed
Kuppers, R. B Cells under Influence: Transformation of B Cells by Epstein-Barr Virus. Nature Reviews Immunology. 2003;3:801–12.Google Scholar
Martinez, OM, de Gruijl, FR. Molecular and Immunologic Mechanisms of Cancer Pathogenesis in Solid Organ Transplant Recipients. American Journal of Transplantation: Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2008;8:2205–11.Google Scholar
Morscio, J, Dierickx, D, Ferreiro, JF, et al. Gene Expression Profiling Reveals Clear Differences between EBV-positive and EBV-negative Posttransplant Lymphoproliferative Disorders. American Journal of Transplantation: Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2013;13:1305–16.CrossRefGoogle ScholarPubMed
Rinaldi, A, Capello, D, Scandurra, M, et al. Single Nucleotide Polymorphism-arrays Provide New Insights in the Pathogenesis of Post-transplant Diffuse Large B-cell Lymphoma. British Journal of Haematology. 2010;149:569–77.Google Scholar
Vakiani, E, Basso, K, Klein, U, et al. Genetic and Phenotypic Analysis of B-cell Post-transplant Lymphoproliferative Disorders Provides Insights into Disease Biology. Hematological Oncology. 2008;26:199211.Google Scholar
Harris, NL, Ferry, JA, Swerdlow, SH. Posttransplant Lymphoproliferative Disorders: Summary of Society for Hematopathology Workshop. Seminars in Diagnostic Pathology. 1997;14:814.Google Scholar
George, LC, Rowe, M, Fox, CP. Epstein-barr Virus and the Pathogenesis of T and NK Lymphoma: A Mystery Unsolved. Current Hematologic Malignancy Reports. 2012;7:276–84.CrossRefGoogle ScholarPubMed
Tiede, C, Maecker-Kolhoff, B, Klein, C, et al. Risk Factors and Prognosis in T-cell Posttransplantation Lymphoproliferative Diseases: Reevaluation of 163 Cases. Transplantation. 2013;95:479–88.Google Scholar
Jonigk, D, Laenger, F, Maegel, L, et al. Molecular and Clinicopathological Analysis of Epstein-Barr Virus-associated Posttransplant Smooth Muscle Tumors. American Journal of Transplantation: Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2012;12:1908–17.Google Scholar
Lee, ES, Locker, J, Nalesnik, M, et al. The Association of Epstein-Barr Virus with Smooth-muscle Tumors Occurring after Organ Transplantation. The New England Journal of Medicine. 1995;332:1925.Google Scholar
Ong, KW, Teo, M, Lee, V, et al. Expression of EBV Latent Antigens, Mammalian Target of Rapamycin, and Tumor Suppression Genes in EBV-positive Smooth Muscle Tumors: Clinical and Therapeutic Implications. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research. 2009;15:5350–8.Google Scholar
Chang, Y, Cesarman, E, Pessin, MS, et al. Identification of Herpesvirus-like DNA Sequences in AIDS-associated Kaposi’s Sarcoma. Science. 1994;266:1865–9.Google Scholar
Mesri, EA, Cesarman, E, Boshoff, C. Kaposi’s Sarcoma and Its Associated Herpesvirus. Nature Reviews Cancer. 2010;10:707–19.Google Scholar
Fukumoto, H, Kanno, T, Hasegawa, H, et al. Pathology of Kaposi’s Sarcoma-associated Herpesvirus Infection. Frontiers in Microbiology. 2011;2:175.Google Scholar
Barozzi, P, Luppi, M, Facchetti, F, et al. Post-transplant Kaposi Sarcoma Originates from the Seeding of Donor-derived Progenitors. Nature Medicine. 2003;9:554–61.Google Scholar
Riva, G, Barozzi, P, Torelli, G, et al. Immunological and Inflammatory Features of Kaposi’s Sarcoma and Other Kaposi’s Sarcoma-associated Herpesvirus/Human Herpesvirus 8-associated Neoplasias. AIDS Reviews. 2010;12:4051.Google Scholar
Arora, R, Chang, Y, Moore, PS. MCV and Merkel Cell Carcinoma: A Molecular Success Story. Current Opinion in Virology. 2012;2:489–98.Google Scholar
Spurgeon, ME, Lambert, PF. Merkel Cell Polyomavirus: A Newly Discovered Human Virus with Oncogenic Potential. Virology. 2013;435:118–30.Google Scholar
Moore, PS, Chang, Y. Why Do Viruses Cause Cancer? Highlights of the First Century of Tumor Virology. Nature Reviews Cancer. 2010;10:878–89.CrossRefGoogle Scholar
Connolly, K, Manders, P, Earls, P, et al. Papillomavirus-associated Squamous Skin Cancers Following Transplant Immunosuppression: One Notch Closer to Control. Cancer Treatment Reviews. 2013.Google Scholar
Deligeoroglou, E, Giannouli, A, Athanasopoulos, N, et al. HPV Infection: Immunological Aspects and Their Utility in Future Therapy. Infectious Diseases in Obstetrics and Gynecology. 2013;2013:540850.Google Scholar
Doorbar, J. Papillomavirus Life Cycle Organization and Biomarker Selection. Disease Markers. 2007;23:297313.Google Scholar
Moody, CA, Laimins, LA. Human Papillomavirus Oncoproteins: Pathways to Transformation. Nature Reviews Cancer. 2010;10:550–60.Google Scholar
Lewis, JS Jr. p16 Immunohistochemistry as a Standalone Test for Risk Stratification in Oropharyngeal Squamous Cell Carcinoma. Head and Neck Pathology. 2012;6 Suppl 1:S7582.Google Scholar
Penn, I. Tumors Arising in Organ Transplant Recipients. Adv Cancer Res. 1978;28:3161.Google Scholar
Penn, I. The Problem of Cancer in Organ Transplant Recipients: An Overview. Transplant Sci. 1994;4:2332.Google Scholar
Nalesnik, MA, Woodle, ES, Dimaio, JM, et al. Donor-transmitted Malignancies in Organ Transplantation: Assessment of Clinical Risk. American Journal of Transplantation. 2011;11:1140–7.Google Scholar
Linder, B, Hong, Y, Jarrett, T. Intra-renal Adrenal Adenoma: A Compelling Addition to the Differential Diagnosis of Renal Mass. International Journal of Urology: Official Journal of the Japanese Urological Association. 2009;16:912–4.CrossRefGoogle Scholar
Bioulac-Sage, P, Cubel, G, Balabaud, C, et al. Revisiting the Pathology of Resected Benign Hepatocellular Nodules Using New Immunohistochemical Markers. Seminars in Liver Disease. 2011;31:91103.Google Scholar
Mazzaferro, V, Regalia, E, Doci, R, et al. Liver Transplantation for the Treatment of Small Hepatocellular Carcinomas in Patients with Cirrhosis. The New England Journal of Medicine. 1996;334:693–9.Google Scholar
American Liver Tumor Study Group. A Randomized Prospective Multi-institutional Trial of Orthotopic Liver Transplantation or Partial Hepatic Resection with or without Adjuvant Chemotherapy for Hepatocellular Carcinoma. Investigators Booklet and Protocol. 1998.Google Scholar
Edge, SB, Byrd, DR, Compton, CC, et al., editors. AJCC Cancer Staging Manual. 7th ed: Springer; 2010.Google Scholar
Bruix, J, Sherman, M, Practice Guidelines Committee AAftSoLD. Management of Hepatocellular Carcinoma. Hepatology (Baltimore, Md). 2005;42:1208–36.Google Scholar
International Consensus Group for Hepatocellular Neoplasia: The International Consensus Group for Hepatocellular N. Pathologic Diagnosis of Early Hepatocellular Carcinoma: A Report of the International Consensus Group for Hepatocellular Neoplasia. Hepatology (Baltimore, Md). 2009;49:658–64.Google Scholar
Bruix, J, Sherman, M, American Association for the Study of Liver D. Management of Hepatocellular Carcinoma: An Update. Hepatology (Baltimore, Md). 2011;53:1020–2.Google Scholar
Klintmalm, GB. Liver Transplantation for Hepatocellular Carcinoma: A Registry Report of the Impact of Tumor Characteristics on Outcome. Annals of Surgery. 1998;228:479–90.Google Scholar
Edmondson, HA, Steiner, PE. Primary Carcinoma of the Liver: A Study of 100 Cases among 48,900 Necropsies. Cancer. 1954;7:462503.Google Scholar
Ishak, KG, Goodman, ZD, Stocker, JT, editors. Atlas of Tumor Pathology. Fascicle 31. Tumors of the Liver and Intrahepatic Bile Ducts. Washington, DC: American Registry of Pathology; 2001.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×