Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-5c6d5d7d68-txr5j Total loading time: 0 Render date: 2024-08-07T02:31:47.608Z Has data issue: false hasContentIssue false

Dictionary

Published online by Cambridge University Press:  03 July 2022

Edited by
Runjan Chetty ,
Kumarasen Cooper ,
Carol Cheung  and
Srinivas Mandavilli
Runjan Chetty
Affiliation:
University of Toronto
Kumarasen Cooper
Affiliation:
University of Pennsylvania
Carol Cheung
Affiliation:
University of Toronto
Srinivas Mandavilli
Affiliation:
Hartford Hospital
Get access
Type
Chapter
Information
Leong's Manual of Diagnostic Biomarkers for Immunohistology , pp. 463 - 490
Publisher: Cambridge University Press
Print publication year: 2022

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Selected references

Galietta, A, Pizzi, C, Pettinato, G, et al. Differential TAG-72 epitope expression in breast cancer and lymph node metastases: A marker of a more aggressive phenotype. Oncol Rep 2002;9:135–40.Google Scholar
Sheibani, K, Esteban, JM, Bailey, A, Battifora, H, Weiss, LM. Immunopathologic and molecular studies as an aid to the diagnosis of malignant mesothelioma. Hum Pathol 1992;23:107–16.CrossRefGoogle Scholar
Szpak, CA, Johnston, WW, Roggli, V, et al. The diagnostic distinction between malignant mesothelioma of the pleura and adenocarcinoma of the lung as defined by a monoclonal antibody B72.3. Am J Pathol 1986;122:252–60.Google Scholar

Selected references

Cork, LC, Sternberger, NH, Sternberger, LA, et al. Phosphorylated neurofilament antigens in neurofibrillary tangles in Alzheimer’s disease. J Neuropathol Exp Neurol 1986;45:56–64.CrossRefGoogle ScholarPubMed
Feany, MB, Dickson, DW. Neurodegenerative disorders with extensive tau pathology: A comparative study and review. Ann Neurol 1996;40:139–48.Google Scholar
Joachim, CL, Morris, JH, Kosik, KS, Selkoe, DJ. Tau antisera recognize neurofibrillary tangles in a range of neurodegenerative disorders. Ann Neurol 1987;22:514–20.Google Scholar

Selected references

Aggarwal, M, Villuendas, R, Gomez, G, et al. TCL1A expression delineates biological and clinical variability in B-cell lymphoma. Mod Pathol 2009;22(2):206–15.Google Scholar
Cao, D, Lane, Z, Allan, RW, et al. TCL1 is a diagnostic marker for intratubular germ cell neoplasia and classic seminoma. Histopathology 2010;57(1):152–7.CrossRefGoogle ScholarPubMed
Laine, J, Kunstle, G, Obata, T, et al. The protooncogene TCL1 is an Akt kinase coactivator. Mol Cell 2000;6:395–407.Google Scholar
Sangle, NA, Schmidt, RL, Patel, JL, et al. Optimized immunohistochemical panel to differentiate myeloid sarcoma from blastic plasmacytoid dendritic cell neoplasm. Mod Pathol 2014;27(8):1137–43.Google Scholar
Sun, Y, Tang, G, Hu, Z, et al. Comparison of karyotyping, TCL1 fluorescence in situ hybridisation and TCL1 immunohistochemistry in T cell prolymphocytic leukaemia. J Clin Pathol 2018;71(4):309–15.Google Scholar
Trinh, DT, Shibata, K, Hirosawa, T, et al. Diagnostic utility of CD117, CD133, SALL4, OCT4, TCL1 and glypican-3 in malignant germ cell tumors of the ovary. J Obstet Gynaecol Res 2012;38(5):841–8.CrossRefGoogle ScholarPubMed
Weissferdt, A, Rodriguez-Canales, J, Liu, H, et al. Primary mediastinal seminomas: A comprehensive immunohistochemical study with a focus on novel markers. Hum Pathol 2015;46(3):376–83.Google Scholar

Selected references

Erickson, HP, Bourdon, MA. Tenascin: An extracellular matrix protein prominent in specialized embryonic tissues and tumors. Ann Rev Cell Biol 1989;5:71–92.Google Scholar
Koukoulis, GK, Gould, VE, Bhattacharyya, A, et al. Tenascin in normal, reactive, hyperplastic and neoplastic tissues: Biologic and pathologic implications. Hum Pathol 1991;22:636–43.CrossRefGoogle ScholarPubMed
Sedele, M, Karaveli, S, Pestereli, HE, et al. Tenascin expression in normal, hyperplastic and neoplastic endometrium. Int J Gynecol Pathol 2002;12:161–6.Google Scholar

Selected references

Chilosi, M, Pizzolo, G. Review of terminal deoxynucleotidyl transferase: Biological aspects, methods of detection, and selected diagnostic applications. Appl Immunohistochem 1995;3:209–21.Google Scholar
Onciu, M, Lorsbach, RB, Henry, EC, et al. Terminal deoxynucleotidyl transferase-positive lymphoid cells in reactive lymph nodes from children with malignant tumor: Incidence, distribution pattern, and immunophenotype in 26 patients. Am J Clin Pathol 2002;118:248–54.Google Scholar
Orazi, A, Cattoretti, G, Joh, K, et al. Terminal deoxynucleotidyl transferase staining of malignant lymphomas in paraffin sections. Mod Pathol 1994;7:582–6.Google Scholar

Selected references

Argani, P, Aulmann, S, Illei, PB, et al. A distinctive subset of PEComas harbors TFE3 gene fusions. Am J Surg Pathol 2010;34:1395–406.Google Scholar
Argani, P, Lal, P, Hutchinson, B, et al. Aberrant nuclear immunoreactivity for TFE3 in neoplasms with TFE3 gene fusions: A sensitive and specific immunohistochemical assay. Am J Surg Pathol 2003;27:750–61.Google Scholar

Selected references

Appleton, MAC, Attanoos, RL, Jasani, B. Thrombomodulin as a marker of vascular and lymphatic tumors. Histopathology 1996;29:153–7.Google Scholar
Attanoos, RL, Goddard, H, Gibbs, AR. Mesothelioma-binding antibodies: Thrombomodulin, OV632 and HBME-1 and their use in the diagnosis of malignant mesothelioma. Histopathology 1996;29:209–15.Google Scholar
Collins, CL, Ordonez, NG, Schaefer, R, et al. Thrombomodulin expression in malignant pleural mesothelioma and pulmonary adenocarcinoma. Am J Pathol 1992;141:827–33.Google Scholar
Ordonez, NG. Value of thrombomodulin immunostaining in the diagnosis of mesothelioma. Histopathology 1997;31:25–30.Google Scholar

Selected references

De Micco, C, Ruf, J, Carayon, P, et al. Immunohistochemical study of thyroglobulin in thyroid carcinomas with monoclonal antibodies. Cancer 1987;59:471–6.Google Scholar
Wilson, NW, Pambakian, H, Richardson, TC, et al. Epithelial markers in thyroid carcinoma: An immunoperoxidase study. Histopathology 1986;10:815–29.Google Scholar

Selected references

Agoff, SN, Lamps, LW, Philip, AT, et al. Thyroid transcription factor-1 is expressed in extrapulmonary small cell carcinomas but not in other extrapulmonary neuroendocrine tumors. Mod Pathol 2000,13:238–42.Google Scholar
Bingle, CD. Thyroid transcription factor-1. Int J Biochem Cell Biol 1997;29:1471–3.CrossRefGoogle ScholarPubMed
Comperat, E, Zhang, F, Perrotin, C, et al. Variable sensitivity and specificity of TTF1 antibodies in lung metastatic adenocarcinoma of colorectal origin. Mod Pathol 2005;18: 1371–6.CrossRefGoogle ScholarPubMed

Selected references

Chen, G, Courey, AJ. Groucho/TLE family proteins and transcriptional repression. Gene 2000;249:1–16.Google Scholar
Duncan, VE, Wicker, JA, Kelly, DR, et al. TLE1 expression in malignant rhabdoid tumor and atypical teratoid/rhabdoid tumor. Pediatr Dev Pathol 2018;21(6):522–7.CrossRefGoogle ScholarPubMed
El Beaino, M, et al. Diagnostic value of TLE1 in synovial sarcoma: A systematic review and meta-analysis. Sarcoma 2020:7192347.CrossRefGoogle Scholar
Foo, WC, Cruise, MW, Wick, MR, et al. Immunohistochemical staining for TLE1 distinguishes synovial sarcoma from histologic mimics. Am J Clin Pathol 2011;135:839–44.Google Scholar
Jagdis, A, Rubin, BP, Tubbs, RR, et al. Prospective evaluation of TLE1 as a diagnostic immunohistochemical marker in synovial sarcoma. Am J Surg Pathol 2009;33:1743–51.CrossRefGoogle ScholarPubMed
Kosemehmetoglu, K, Vrana, JA, Folpe, AL. TLE1 expression is not specific for synovial sarcoma: A whole section study of 163 soft tissue and bone neoplasms. Mod Pathol 2009;22(7):872–8.Google Scholar
Li, WS, Liao, IC, Wen, MC, et al. BCOR-CCNB3-positive soft tissue sarcoma with round-cell and spindle-cell histology: A series of four cases highlighting the pitfall of mimicking poorly differentiated synovial sarcoma. Histopathology 2016;69(5):792–801.Google Scholar
Pukhalskaya, T, Smoller, BR. TLE1 expression fails to distinguish between synovial sarcoma, atypical fibroxanthoma, and dermatofibrosarcoma protuberans. J Cutan Pathol 2020;47(2):135–8.Google Scholar
Terry, J, Saito, T, Subramanian, S, et al. TLE1 as a diagnostic immunohistochemical marker for synovial sarcoma emerging from gene expression profiling studies. Am J Surg Pathol 2007;31(2):240–6.Google Scholar
Zaccarini, DJ, Deng, X, Tull, J, et al. Expression of TLE-1 and CD99 in carcinoma: Pitfalls in diagnosis of synovial sarcoma. Appl Immunohistochem Mol Morphol 2018;26(6):368–73.CrossRefGoogle ScholarPubMed

Selected references

Di Leo, A, Larsimont, D, Gancberg, D, et al. HER-2 and topoisomerase II alpha as predictive markers in a population of node-positive breast cancer patients randomly treated with adjuvant CMF or epirubicin plus cyclophosphamide. Ann Oncol 2001;12:1081–9.Google Scholar
Gotleib, WH, Goldberg, I, Weisz, B, et al. Topoisomerase II immunostaining as a prognostic marker for survival in ovarian cancer. Gynecol Oncol 2001;82:99–104.CrossRefGoogle Scholar

Selected references

Conley, FK, Jenkins, KA, Remington, JS. Toxoplasma gondii infection of the central nervous system: Use of the peroxidase-antiperoxidase method to demonstrate Toxoplasma in formalin-fixed, paraffin-embedded tissue sections. Hum Pathol 1981;12:690–8.Google Scholar
Kriek, JA, Remington, JS. Toxoplasmosis in the adult – an overview. N Engl J Med 1978;298:550–3.Google Scholar

Selected references

Hofbauer, GF, Kamarashev, J, Geertsen, R, et al. Tyrosinase immunoreactivity in formalin-fixed, paraffin-embedded primary and metastatic melanoma: Frequency and distribution. J Cutan Pathol 1998;25:204–9.Google Scholar
Jungbluth, AA, Iversen, K, Copian, K, et al. T311 – an anti-tyrosinase monoclonal antibody for the detection of melanocytic lesions in paraffin embedded tissues. Pathol Res Pract 2000;196:235–42.Google Scholar
Kaufmann, O, Koch, S, Burghardt, J, et al. Tyrosinase, Melan-A, and KBA62 as markers for the immunohistochemical identification of metastatic amelanotic melanomas on paraffin sections. Mod Pathol 1998;11:740–6.Google Scholar

Selected references

Ceccamea, A, Carlei, F, Dominici, C, et al. Correlation between tyrosine hydroxylase immunoreactive cells in tumors and urinary catecholamine output in neuroblastoma patients. Tumori 1986 31;72(5):451–7.CrossRefGoogle ScholarPubMed
Iwase, K, Nagasaka, A, Nagatsu, I, et al. Tyrosine hydroxylase indicates cell differentiation of catecholamine biosynthesis in neuroendocrine tumors. J Endocrinol Invest 1994;17:235–9.Google Scholar
Meijer, WG, Copray, SC, Hollema, H, et al. Catecholamine-synthesizing enzymes in carcinoid tumors and pheochromocytomas. Clin Chem 2003;49:586–93.Google Scholar
Takahashi, H, Wakabayashi, K, Ikuta, F, et al. Esthesioneuroblastoma: A nasal catecholamine-producing tumor of neural crest origin. Demonstration of tyrosine hydroxylase-immunoreactive tumor cells. Acta Neuropathol 1988;76:522–7.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×